Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Anna Leonidova"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:7364-7371
One of the major neglected tropical diseases, schistosomiasis, is currently treated and controlled with a single drug, praziquantel. The quest for an alternative drug is fueled by the lack of activity of praziquantel against juvenile Schistosoma worm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25e568935ef1db1ac38a7cc95dbebba
https://doi.org/10.1128/aac.02394-15
https://doi.org/10.1128/aac.02394-15
Publikováno v:
Organometallics. 35:851-854
Histone deacetylases (HDACs) are regarded as promising targets in cancer and a growing number of other diseases due to their crucial involvement in epigenetics and cellular signaling. Many organic HDAC inhibitors are known, and several efficient meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cad88cc24246fbbc086cdaff4e88e2
https://doi.org/10.1021/acs.organomet.6b00029
https://doi.org/10.1021/acs.organomet.6b00029
Publikováno v:
European Journal of Inorganic Chemistry. 2015:3879-3891
Photoactivated chemotherapy (PACT) relies on the use of a drug and light to cause cell death. Unlike photodynamic therapy (PDT), its mechanism of action is independent of the presence of oxygen in tissues. This approach is therefore also effective fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3703e833d1ff62d671606ec9455b68bd
https://doi.org/10.1002/ejic.201500602
https://doi.org/10.1002/ejic.201500602
Autor:
Hans-Jürgen Pietzsch, Jörg Steinbach, Anna Leonidova, Holger Stephan, Maik Schubert, Gilles Gasser, Christian Foerster, Ralf Bergmann, Nils Metzler-Nolte, Kristof Zarschler
Publikováno v:
Chemical Science. 6:5601-5616
A novel, promising strategy for cancer diagnosis and therapy is the use of a pretargeting approach. For this purpose, the non-natural DNA/RNA analogues Peptide Nucleic Acids (PNAs) are ideal candidates as in vivo recognition units due to their high m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f699b3bd6c59c8bbcedf9eded26bd4
https://doi.org/10.1039/c5sc00951k
https://doi.org/10.1039/c5sc00951k
Publikováno v:
Chemphyschem : a European journal of chemical physics and physical chemistry
Following a recent communication on the determination of quantum yields for ultraviolet-A-induced photouncaging written by a few of us (P.A. , A.L. , and G.G.), Dr. Trentham contacted ChemPhysChem because he doubted the experimental results presented
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a664e5ea371b12f900c4db2c81807a
Autor:
Gilles Gasser, Anna Leonidova
Publikováno v:
ACS Chemical Biology. 9:2180-2193
In the recent years, organometallic compounds have become recognized as promising anti-cancer drug candidates. While radioactive (186/188)Re compounds are already used in clinics for cancer treatment, cold Re organometallic compounds have mostly been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7aa578a4bad87c34bde5cb5f3a71755
https://doi.org/10.1021/cb500528c
https://doi.org/10.1021/cb500528c
Autor:
Philipp Anstaett, Anna Leonidova, Gilles Gasser, Vanessa Pierroz, Stefano Ferrari, Bernhard Spingler, Cristina Mari
Publikováno v:
Inorganic chemistry. 54(20)
Reactive oxygen species (ROS)-activated aminoferrocene-based anticancer prodrug candidates successfully take advantage of intrinsically high amounts of ROS in tumor tissues. Interestingly, the ROS-initiated activation of these prodrug candidates lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22caa721d853ceb384399ed8d9347fda
https://pubmed.ncbi.nlm.nih.gov/26440628
https://pubmed.ncbi.nlm.nih.gov/26440628
The quantum yields for photouncaging reactions are mostly determined relative to other uncaging reactions, often using 1-(2-nitrophenyl)ethyl-phosphate ("caged phosphate"). Herein, we demonstrate that the quantum yields acquired by using this method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b42b72cc33b2a0260ff850d0b7ca39
https://www.zora.uzh.ch/id/eprint/114189/
https://www.zora.uzh.ch/id/eprint/114189/
Autor:
Vanessa Pierroz, Anna Leonidova, Stefano Ferrari, Nicholas Barlow, Luke A. Adams, Bimbil Graham, Gilles Gasser
Re(I) tricarbonyl polypyridine-based complexes are particularly attractive metal complexes in the field of inorganic chemical biology due to their luminescent properties, ease of conjugation to targeting biomolecules, and the possibility to prepare t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69403ac9d9009f22a3e31e3fc972859
https://www.zora.uzh.ch/id/eprint/98805/
https://www.zora.uzh.ch/id/eprint/98805/
Autor:
Suzan Can, Roberto Molteni, Nils Metzler-Nolte, Vanessa Pierroz, Stefan Wölfl, Hamed Alborzinia, Andreas Steffen, Igor Kitanovic, Stefano Ferrari, António Costa Pinto, Ana Kitanovic, Gilles Gasser, Anna Leonidova, Bernhard Spingler
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 20(9)
The photophysical properties of [Re(CO)3 (L-N3)]Br (L-N3 =2-azido-N,N-bis[(quinolin-2-yl)methyl]ethanamine), which could not be localized in cancer cells by fluorescence microscopy, have been revisited in order to evaluate its use as a luminescent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578aaccf6ea88fa9e413d0d404e96fd6
https://pubmed.ncbi.nlm.nih.gov/24464824
https://pubmed.ncbi.nlm.nih.gov/24464824