Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anna Lena Woelke"'
Autor:
Anna Lena Woelke, Joachim von Eichborn, Manuela S Murgueitio, Catherine L Worth, Filippo Castiglione, Robert Preissner
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23257 (2011)
Peptide vaccination in cancer therapy is a promising alternative to conventional methods. However, the parameters for this personalized treatment are difficult to access experimentally. In this respect, in silico models can help to narrow down the pa
Externí odkaz:
https://doaj.org/article/f09705e609a74d3ea0c47dcf8f3541b4
Publikováno v:
Clinical and Developmental Immunology, Vol 2010 (2010)
Currently, cancer is one of the leading causes of death in industrial nations. While conventional cancer treatment usually results in the patient suffering from severe side effects, immunotherapy is a promising alternative. Nevertheless, some questio
Externí odkaz:
https://doaj.org/article/532082d83763449cb000cdefda0b5f68
Autor:
Anna Lena Woelke, Ulrike Alexiev, Juliane Wonneberg, Milan Hodoscek, Ernst-Walter Knapp, Alexander Wolf, Jens Balke, Jovan Dragelj, Johannes Stellmacher
Publikováno v:
Chemical Science. 11:3804-3811
Cytochrome c oxidase (CcO), a redox-coupled proton pump, catalyzes the reduction of molecular oxygen to water, thereby establishing the transmembrane proton gradient that fuels ATP synthesis. CcO employs two channels for proton uptake, the D- and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6881873805b0226689920cf623ada35
https://doi.org/10.1039/c9sc06463j
https://doi.org/10.1039/c9sc06463j
Autor:
Inez M. Weidinger, Murat Sezer, Ernst-Walter Knapp, Ramona Schlesinger, Maria Andrea Mroginski, Anna Lena Woelke
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1858:103-108
Understanding the coupling between heme reduction and proton translocation in cytochrome c oxidase (CcO) is still an open problem. The propionic acids of heme a3 have been proposed to act as a proton loading site (PLS) in the proton pumping pathway,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853f3238bb6ce402392e9f116637feda
https://doi.org/10.1016/j.bbabio.2016.10.009
https://doi.org/10.1016/j.bbabio.2016.10.009
Autor:
Petra Imhof, Mahdi Bagherpoor Helabad, Marco Reidelbach, Ernst-Walter Knapp, Anna Lena Woelke, Tahereh Ghane
Publikováno v:
Biophysical journal. 113(1)
Proton transfer in cytochrome c oxidase from the cellular inside to the binuclear redox center (BNC) can occur through two distinct pathways, the D- and K-channels. For the protein to function as both redox enzyme and proton pump, proton transfer out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e8aa7e6b3c6793b493543577620990
https://pubmed.ncbi.nlm.nih.gov/27508434
https://pubmed.ncbi.nlm.nih.gov/27508434
Autor:
Mahdi Bagherpoor Helabad, Tahereh Ghane, Petra Imhof, Ernst-Walter Knapp, Anna Lena Woelke, Marco Reidelbach
Publikováno v:
Biophysical journal. 113(4)
Proton transfer in cytochrome c oxidase from the cellular inside to the binuclear redox center (BNC) can occur through two distinct pathways, the D- and K-channels. For the protein to function as both redox enzyme and proton pump, proton transfer out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd75cba13dc4a3967a4e83ef84b1da0
https://pubmed.ncbi.nlm.nih.gov/28834718
https://pubmed.ncbi.nlm.nih.gov/28834718
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1837(12):1998-2003
The metabolism of aerobic life uses the conversion of molecular oxygen to water as an energy source. This reaction is catalyzed by cytochrome c oxidase (CcO) consuming four electrons and four protons, which move along specific routes. While all four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670232e091ed62de2c6fee312f23a909
Publikováno v:
Biophysical Journal. 107:2177-2184
A key enzyme in aerobic metabolism is cytochrome c oxidase (CcO), which catalyzes the reduction of molecular oxygen to water in the mitochondrial and bacterial membranes. Substrate electrons and protons are taken up from different sides of the membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b17777d744cca69d5884d9bef4b9086
https://doi.org/10.1016/j.bpj.2014.09.010
https://doi.org/10.1016/j.bpj.2014.09.010
Autor:
Anna Lena Woelke, Tim Meyer, Gegham Galstyan, Christian Kuehne, Jens Dernedde, Ernst-Walter Knapp
Publikováno v:
The Journal of Physical Chemistry B. 117:16443-16454
Higher organisms defend themselves against invading micro-organisms and harmful substances with their immune system. Key players of the immune system are the white blood cells (WBC), which in case of infection move in an extravasation process from bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8c8b19d2136f6645ebf852f0e52e0
https://doi.org/10.1021/jp4099123
https://doi.org/10.1021/jp4099123
Autor:
Gegham Galstyan, Tim Meyer, Ernst-Walter Knapp, Artur Galstyan, Anna Lena Woelke, Joachim Heberle
Publikováno v:
The Journal of Physical Chemistry B. 117:12432-12441
Cytochrome c oxidase (CcO) is a central enzyme in aerobic life catalyzing the conversion of molecular oxygen to water and utilizing the chemical energy to pump protons and establish an electrochemical gradient. Despite intense research, it is not und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa0cf53d78c268646a75d3e7da264ee
https://doi.org/10.1021/jp407250d
https://doi.org/10.1021/jp407250d