Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anna Lena Jung"'
Autor:
Marie Burt, Georgia Angelidou, Christopher Nils Mais, Christian Preußer, Timo Glatter, Thomas Heimerl, Rüdiger Groß, Javier Serrania, Gowtham Boosarpu, Elke Pogge von Strandmann, Janis A. Müller, Gert Bange, Anke Becker, Mareike Lehmann, Danny Jonigk, Lavinia Neubert, Hinrich Freitag, Nicole Paczia, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract The continuous emergence of multidrug‐resistant bacterial pathogens poses a major global healthcare challenge, with Klebsiella pneumoniae being a prominent threat. We conducted a comprehensive study on K. pneumoniae’s antibiotic resistan
Externí odkaz:
https://doaj.org/article/d578823b51904a85bb20616a75988ddc
Autor:
Amir Pandi, David Adam, Amir Zare, Van Tuan Trinh, Stefan L. Schaefer, Marie Burt, Björn Klabunde, Elizaveta Bobkova, Manish Kushwaha, Yeganeh Foroughijabbari, Peter Braun, Christoph Spahn, Christian Preußer, Elke Pogge von Strandmann, Helge B. Bode, Heiner von Buttlar, Wilhelm Bertrams, Anna Lena Jung, Frank Abendroth, Bernd Schmeck, Gerhard Hummer, Olalla Vázquez, Tobias J. Erb
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Bioactive peptides are key molecules in health and medicine. Deep learning holds a big promise for the discovery and design of bioactive peptides. Yet, suitable experimental approaches are required to validate candidates in high throughput a
Externí odkaz:
https://doaj.org/article/adbbacf7db9c45aca2f0981cf0f79344
Autor:
Björn Klabunde, André Wesener, Wilhelm Bertrams, Isabell Beinborn, Nicole Paczia, Kristin Surmann, Sascha Blankenburg, Jochen Wilhelm, Javier Serrania, Kèvin Knoops, Eslam M. Elsayed, Katrin Laakmann, Anna Lena Jung, Andreas Kirschbaum, Sven Hammerschmidt, Belal Alshaar, Nicolas Gisch, Mobarak Abu Mraheil, Anke Becker, Uwe Völker, Evelyn Vollmeister, Birke J. Benedikter, Bernd Schmeck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic l
Externí odkaz:
https://doaj.org/article/f53e17d7ffee4a8b866fd16db80c5bb8
Autor:
Fiona Starke, Alexandra Sikora, Ralf Stegmann, Leonie Knebel, Claudia Buntrock, Angelique de Rijk, Inge Houkes, Gregor R. Szycik, Hans-Peter Unger, Jan Ole Schumacher, Heiko Stark, Iris Hauth, Christian Holzapfel, Anna Borgolte, Carlotta Schneller, Sarah-Louise Unterschemmann, Wiebke Paetow, Anna Lena Jung, Matthias Berking, Johannes Zimmermann, Uta Wegewitz
Publikováno v:
BMC Psychiatry, Vol 23, Iss 1, Pp 1-20 (2023)
Abstract Background Mental disorders (MDs) are one of the leading causes for workforce sickness absence and disability worldwide. The burden, costs and challenges are enormous for the individuals concerned, employers and society at large. Although mo
Externí odkaz:
https://doaj.org/article/65949897b58e4af29c3cfabd7e9097ea
Autor:
Katrin Laakmann, Jorina Mona Eckersberg, Moritz Hapke, Marie Wiegand, Jeff Bierwagen, Isabell Beinborn, Christian Preußer, Elke Pogge von Strandmann, Thomas Heimerl, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Sepsis is one of the leading causes of death worldwide and characterized by blood stream infections associated with a dysregulated host response and endothelial cell (EC) dysfunction. Ribonuclease 1 (RNase1) acts as a protective f
Externí odkaz:
https://doaj.org/article/7c0269688b8b458fb4d7267fe2e39b81
Autor:
Jeff Bierwagen, Marie Wiegand, Katrin Laakmann, Olga Danov, Hannah Limburg, Stefanie Muriel Herbel, Thomas Heimerl, Jens Dorna, Danny Jonigk, Christian Preußer, Wilhelm Bertrams, Armin Braun, Katherina Sewald, Leon N. Schulte, Stefan Bauer, Elke Pogge von Strandmann, Eva Böttcher-Friebertshäuser, Bernd Schmeck, Anna Lena Jung
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transported PAMPs. As important reside
Externí odkaz:
https://doaj.org/article/5ab97f46113346758e29ef1c0e67adfd
Autor:
Stefanie M. Herbel, Lambert Moyon, Marvin Christ, Eslam M. Elsayed, Brian E. Caffrey, Silke Malmsheimer, Iwan Grin, Kerstin Hoffmann, Kristin Surmann, Sascha Blankenburg, Anna Lena Jung, Christina E. Herkt, Marco Borsò, Beyza Bozdag, Axel Imhof, Anke Becker, Samuel Wagner, Gert Bange, Uwe Völker, Wilhelm Bertrams, Annalisa Marsico, Bernd Schmeck
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 2042-2058 (2022)
Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and the tran
Externí odkaz:
https://doaj.org/article/3cfbe5db3b0f4145a005db5fed54388b
Autor:
Anna Lena Jung, Maria Han, Kathrin Griss, Wilhelm Bertrams, Christoph Nell, Timm Greulich, Andreas Klemmer, Hendrik Pott, Dominik Heider, Claus F. Vogelmeier, Stefan Hippenstiel, Norbert Suttorp, Bernd Schmeck
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionCommunity-acquired pneumonia (CAP) and acute exacerbations of chronic obstructive pulmonary disease (AECOPD) result in high morbidity, mortality, and socio-economic burden. The usage of easily accessible biomarkers informing on disease en
Externí odkaz:
https://doaj.org/article/19100ed459f44882b71674f7d9a3346d
Autor:
Anna Lena Jung, Christina Elena Herkt, Christine Schulz, Kathrin Bolte, Kerstin Seidel, Nicoletta Scheller, Alexandra Sittka-Stark, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Extracellular vesicles from eukaryotic cells and outer membrane vesicles (OMVs) released from gram-negative bacteria have been described as mediators of pathogen-host interaction and intercellular communication. Legionella pneumophila (L. pn
Externí odkaz:
https://doaj.org/article/634e435cb02945d984a05ad1940c1919
Legionella pneumophila-Derived Outer Membrane Vesicles Promote Bacterial Replication in Macrophages.
Autor:
Anna Lena Jung, Cornelia Stoiber, Christina E Herkt, Christine Schulz, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005592 (2016)
The formation and release of outer membrane vesicles (OMVs) is a phenomenon of Gram-negative bacteria. This includes Legionella pneumophila (L. pneumophila), a causative agent of severe pneumonia. Upon its transmission into the lung, L. pneumophila p
Externí odkaz:
https://doaj.org/article/08b93d38d74c4ba9b113e032b730f90e