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Autor:
Janine Mayer, Jan Pippel, Gabriele Günther, Carolin Müller, Anna Lauermann, Tobias Knuuti, Wulf Blankenfeldt, Dieter Jahn, Rebekka Biedendieck
Publikováno v:
Applied microbiology and biotechnology
Penicillin G acylase (PGA) catalyzes the hydrolysis of penicillin G to 6-aminopenicillanic acid and phenylacetic acid, which provides the precursor for most semisynthetic penicillins. Most applications rely on PGAs from Gram-negative bacteria. Here w