Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Anna Lastuvkova"'
Autor:
Amy L. Hughes, Aleksander T. Szczurek, Jessica R. Kelley, Anna Lastuvkova, Anne H. Turberfield, Emilia Dimitrova, Neil P. Blackledge, Robert J. Klose
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here the authors discover that SET1 complexes function as transcription anti-termination factors that bind to CpG islands and protect low to moderately transcribed genes from the pervasive termination activity of the ZC3H4 complex.
Externí odkaz:
https://doaj.org/article/fa7131c1d5964b9e91a8afdc60047753
Publikováno v:
Nucleic Acids Research
Appropriate developmental gene regulation relies on the capacity of gene promoters to integrate inputs from distal regulatory elements, yet how this is achieved remains poorly understood. In embryonic stem cells (ESCs), a subset of silent development
Autor:
Emilia Dimitrova, Angelika Feldmann, Robin H. van der Weide, Koen D. Flach, Anna Lastuvkova, Elzo de Wit, Robert J. Klose
Publikováno v:
Nature structuralmolecular biology. 29(10)
Precise control of gene expression underpins normal development. This relies on mechanisms that enable communication between gene promoters and other regulatory elements. In embryonic stem cells (ESCs), the cyclin-dependent kinase module Mediator com
Autor:
Anna Lastuvkova, Anne H. Turberfield, Paula Dobrinić, Neil P. Blackledge, Nadezda A. Fursova, Miles K. Huseyin, Robert J. Klose, Emma L. Findlater
Publikováno v:
Genes & Development
bioRxiv
Genes Dev
bioRxiv
Genes Dev
Histone-modifying systems play fundamental roles in gene regulation and the development of multicellular organisms. Histone modifications that are enriched at gene regulatory elements have been heavily studied, but the function of modifications found
Autor:
Hughes, Amy L., Szczurek, Aleksander T., Kelley, Jessica R., Lastuvkova, Anna, Turberfield, Anne H., Dimitrova, Emilia, Blackledge, Neil P., Klose, Robert J.
Publikováno v:
Nature Communications; 2/9/2023, Vol. 14 Issue 1, p1-19, 19p
Publikováno v:
Nucleic Acids Research; 4/6/2020, Vol. 48 Issue 6, p2942-2955, 14p