Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Anna Lappala"'
Autor:
Carlos Rivera, Hun-Goo Lee, Anna Lappala, Danni Wang, Verónica Noches, Montserrat Olivares-Costa, Marcela Sjöberg-Herrera, Jeannie T. Lee, María Estela Andrés
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The classical neuronal-gene corepressor RCOR1/CoREST is paradoxically enriched in transcriptionally active chromatin. Here the authors show RCOR1 is recruited during promoter-proximal pausing and negatively regulates the nascent-transcript synthesis.
Externí odkaz:
https://doaj.org/article/81f3099598404a4dbd4c6e911f8205fd
Autor:
Carlos Rivera, Daniel Verbel-Vergara, Duxan Arancibia, Anna Lappala, Marcela González, Fabián Guzmán, Gianluca Merello, Jeannie T. Lee, María Estela Andrés
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract Background Nuclear processes such as transcription and RNA maturation can be impacted by subnuclear compartmentalization in condensates and nuclear bodies. Here, we characterize the nature of nuclear granules formed by REST corepressor 2 (RC
Externí odkaz:
https://doaj.org/article/1e42156d4a4f407eafaaf66356ce3bbc
Autor:
Jacob C. Miner, Anna Lappala, Paul W. Fenimore, William M. Fischer, Benjamin H. McMahon, Nicolas W. Hengartner, Karissa Y. Sanbonmatsu, Chang-Shung Tung
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 124 (2021)
Seasonal flu is an acute respiratory disease that exacts a massive toll on human populations, healthcare systems and economies. The disease is caused by an enveloped Influenza virus containing eight ribonucleoprotein (RNP) complexes. Each RNP incorpo
Externí odkaz:
https://doaj.org/article/dd2866bbea854faa8d13e4ff9feb6e21
Autor:
Anna Lappala, Wataru Nishima, Jacob Miner, Paul Fenimore, Will Fischer, Peter Hraber, Ming Zhang, Benjamin McMahon, Chang-Shung Tung
Publikováno v:
Biomolecules, Vol 8, Iss 2, p 25 (2018)
Membrane fusion proteins are responsible for viral entry into host cells—a crucial first step in viral infection. These proteins undergo large conformational changes from pre-fusion to fusion-initiation structures, and, despite differences in viral
Externí odkaz:
https://doaj.org/article/6b3dcf76fe7042d9ba02ddfc024ef92c
Autor:
Duxan Arancibia, Anna Lappala, Fabián Guzmán, Carlos A. Rivera, Jeannie T. Lee, Daniel Verbel-Vergara, María Estela Andrés, Marcela González, Gianluca Merello
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-15 (2021)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background Nuclear processes such as transcription and RNA maturation can be impacted by subnuclear compartmentalization in condensates and nuclear bodies. Here, we characterize the nature of nuclear granules formed by REST corepressor 2 (RCOR2), a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b2986a62b14b7fc322daf2b42f3b6b5
https://doi.org/10.21203/rs.3.rs-978769/v1
https://doi.org/10.21203/rs.3.rs-978769/v1
Autor:
Jeannie T. Lee, Kevin M. Tan, Anna Lappala, Karissa Y. Sanbonmatsu, Chen-Yu Wang, Andrea J. Kriz, Hunter Michalk
Publikováno v:
Proc Natl Acad Sci U S A
Chromosomes are segmented into domains and compartments, but how these structures are spatially related in three dimensions (3D) is unclear. Here, we developed tools that directly extract 3D information from Hi-C experiments and integrate the data ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc8ffa0709a5aa03bbdf98ce0dd0a77
https://doi.org/10.1073/pnas.2107092118
https://doi.org/10.1073/pnas.2107092118
Autor:
Chigusa Kobayashi, Wataru Nishima, Anna Lappala, Will Fischer, Marcus Daniels, Jaewoon Jung, Tamar Schlick, Karissa Y. Sanbonmatsu, Dominic Phillips, Gavin D. Bascom, Yuji Sugita, Chang-Shung Tung, Adetokunbo Adedoyin, Michael E. Wall
Publikováno v:
J Comput Chem
The growing interest in the complexity of biological interactions is continuously driving the need to increase system size in biophysical simulations, requiring not only powerful and advanced hardware but adaptable software that can accommodate a lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf049658b724aa4bff403e0981c8ace
https://doi.org/10.1002/jcc.25840
https://doi.org/10.1002/jcc.25840
Autor:
Jeannie T. Lee, Anna Lappala, Karissa Y. Sanbonmatsu, Kevin M. Tan, Chaolong Wang, Andrea J. Kriz, Michalk H
Chromosomes are segmented into domains and compartments; yet, how these structures are spatially related in 3D is unclear. Here, by directly integrating Hi-C capture experiments and 3D modeling, we use X-inactivation as a model to examine the time ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e3a3ad0fdfa9adc1284a6b6d52c875
https://doi.org/10.1101/2021.01.21.427652
https://doi.org/10.1101/2021.01.21.427652
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
The glass transition is one of the few unsolved problems in condensed matter physics: agreement on the cause of the slowing down of structural relaxation in glass-forming liquids is lacking. Glasses are amorphous solids, which do not possess the long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d45a1e066d58df9418aafd1f7b5c45
https://pubmed.ncbi.nlm.nih.gov/30846731
https://pubmed.ncbi.nlm.nih.gov/30846731
Autor:
Chang-Shung Tung, Paul W. Fenimore, Benjamin H. McMahon, Ming Zhang, Wataru Nishima, Anna Lappala, Peter T. Hraber, Jacob C. Miner, Will Fischer
Publikováno v:
Biomolecules; Volume 8; Issue 2; Pages: 25
Biomolecules, Vol 8, Iss 2, p 25 (2018)
Biomolecules
Biomolecules, Vol 8, Iss 2, p 25 (2018)
Biomolecules
Membrane fusion proteins are responsible for viral entry into host cells—a crucial first step in viral infection. These proteins undergo large conformational changes from pre-fusion to fusion-initiation structures, and, despite differences in viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b569ac5994ddc2924ba9d2a3c794ec16