Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Anna Laitakari"'
Autor:
Anna Laitakari, Teemu Ollonen, Thomas Kietzmann, Gail Walkinshaw, Daniela Mennerich, Valerio Izzi, Kirsi-Maria Haapasaari, Johanna Myllyharju, Raisa Serpi, Elitsa Y. Dimova, Peppi Koivunen
Publikováno v:
Redox Biology, Vol 22, Iss , Pp - (2019)
Alcoholic fatty liver disease (AFLD) is a growing health problem for which no targeted therapy is available. We set out to study whether systemic inactivation of the main hypoxia-inducible factor prolyl 4-hydroxylase, HIF-P4H-2 (PHD2/EglN1), whose in
Externí odkaz:
https://doaj.org/article/6bb2762c679b4b848641c82d1549d47d
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 3872 (2021)
The G-protein coupled receptor GPR39 is abundantly expressed in various tissues and can be activated by changes in extracellular Zn2+ in physiological concentrations. Previously, genetically modified rodent models have been able to shed some light on
Externí odkaz:
https://doaj.org/article/ca3ed5a823db4b67b31f9b5329936114
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Visualization of basal cell surface of ANGPT2-GFP HUVECs during cell spreading.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cec62beb0505fbc1725b2ab10c1d54c
https://doi.org/10.1158/0008-5472.22426509
https://doi.org/10.1158/0008-5472.22426509
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Supplementary Figure S1: Amino acid sequence of ANGPT2, ANGPT2443 and ANGTPT2DAP. Supplementary Figure S2: Competitive inhibition of ANGPT4-induced TIE2 phosphorylation by ANGPT2 isoforms. Supplementary Figure S3. TIE2 phosphorylation by ANGPT2 isofo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48eb29cab98bf33eb845539dd7992c3f
https://doi.org/10.1158/0008-5472.22426518
https://doi.org/10.1158/0008-5472.22426518
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Angiopoietin-2 (ANGPT2) is a context-dependent TIE2 agonistic or antagonistic ligand that induces diverse responses in cancer. Blocking ANGPT2 provides a promising strategy for inhibiting tumor growth and metastasis, yet variable effects of targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f11b00faa0ce8b7dc41393cd27efe7e1
https://doi.org/10.1158/0008-5472.c.6512358.v1
https://doi.org/10.1158/0008-5472.c.6512358.v1
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Supplementary Tables I-III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae0bf93ba1985d4c50d2f82803fd8c3
https://doi.org/10.1158/0008-5472.22426506
https://doi.org/10.1158/0008-5472.22426506
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Visualization of basal cell surface of GFP-HUVECs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2911e042eb3215c349ed283cdd0e0f
https://doi.org/10.1158/0008-5472.22426512
https://doi.org/10.1158/0008-5472.22426512
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Legends for Sup movies 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533aef1f39ecac00dbebbe30835a23f7
https://doi.org/10.1158/0008-5472.22426503
https://doi.org/10.1158/0008-5472.22426503
Autor:
Lauri Eklund, Harri Elamaa, Taina Pihlajaniemi, Lloyd Ruddock, Gong-Hong Wei, Qin Zhang, Mohammadhassan Ansarizadeh, Anna Laitakari, Ilkka Miinalainen, Raman Devarajan, Anne Heikkinen, Hongmin Tu, Veli-Pekka Ronkainen, Mika Kaakinen, Riikka Pietilä, Minna K. Kihlström, Emmi Kapiainen
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f3abee8b7c31d44a9f666b447674aea
https://doi.org/10.1158/0008-5472.22426515.v1
https://doi.org/10.1158/0008-5472.22426515.v1
Autor:
Lloyd W. Ruddock, Ilkka Miinalainen, Mohammadhassan Ansarizadeh, Anna Laitakari, Mika Kaakinen, Emmi Kapiainen, Qin Zhang, Gong-Hong Wei, Veli-Pekka Ronkainen, Hongmin Tu, Taina Pihlajaniemi, Raman Devarajan, Harri Elamaa, Lauri Eklund, Riikka Pietila, Anne Heikkinen, Minna Kihlström
Publikováno v:
Cancer Research. 81:129-143
Angiopoietin-2 (ANGPT2) is a context-dependent TIE2 agonistic or antagonistic ligand that induces diverse responses in cancer. Blocking ANGPT2 provides a promising strategy for inhibiting tumor growth and metastasis, yet variable effects of targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c652f53f21493658f124db0f27580e90
https://doi.org/10.1158/0008-5472.can-19-1904
https://doi.org/10.1158/0008-5472.can-19-1904