Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anna L. Win"'
Autor:
Mattie S. M. Timmer, Emma M. Dangerfield, Stephen G. Withers, Seino A. K. Jongkees, Bridget L. Stocker, Anna L. Win-Mason
Publikováno v:
Carbohydrate Research. 367:29-32
The ability of a series of pyrrolidines to inhibit several glycosidases was investigated. Using Fleet’s ‘mirror-image postulate’, it was proposed that enantiomeric derivatives of 1,4-dideoxy-1,4-imino- d -lyxitol (a known α- d -galactosidase i
Autor:
Peter C. Tyler, Emma M. Dangerfield, Mattie S. M. Timmer, Bridget L. Stocker, Anna L. Win-Mason
Publikováno v:
European Journal of Organic Chemistry. 2011:4008-4014
An efficient and highly stereoselective synthesis of L-ido-aminoiminosugar 3 has been described. Key in the synthesis is the application of a diastereoselective Strecker reaction and the extension of our carbamate annulation methodology to protected
Autor:
Catherine H. Plunkett, Emma M. Dangerfield, Bridget L. Stocker, Anna L. Win-Mason, Mattie S. M. Timmer
Publikováno v:
The Journal of Organic Chemistry. 75:5470-5477
New methodology for the protecting-group-free synthesis of primary amines is presented. By optimizing the metal hydride/ammonia mediated reductive amination of aldehydes and hemiacetals, primary amines were selectively prepared with no or minimal for
Autor:
Emma M. Dangerfield, Mattie S. M. Timmer, Gregory W. Haslett, Anna L. Win-Mason, Bridget L. Stocker
Publikováno v:
European Journal of Organic Chemistry. 2010:1615-1637
As noted inhibitors of glycosidases, iminosugars have enormous therapeutic potential in the treatment of a number of diseases such as cancer, diabetes, and lysosomal storage disorders. Accordingly, much effort has been expended over the past decades
Publikováno v:
ChemInform. 43
Publikováno v:
Carbohydrate research. 356
The I 2 -mediated carbamate annulation provides an efficient and highly stereoselective route for the synthesis of a variety of pyrrolidines and piperidines, both in the presence and absence of protecting groups. Evidence for the formation of an iodo
Autor:
Mattie S. M. Timmer, Anna L. Win-Mason, Stephen G. Withers, Seino A. K. Jongkees, Bridget L. Stocker, Peter C. Tyler
Publikováno v:
The Journal of organic chemistry. 76(23)
New methodology for the preparation of a variety of aminoiminohextitols is described. Key in the synthesis is the application of a diastereoselective Strecker reaction and the extension of our carbamate annulation methodology to protected and functio
Autor:
Catherine H. Plunkett, Anna L. Win-Mason, Bridget L. Stocker, Mattie S. M. Timmer, Emma M. Dangerfield
Publikováno v:
ChemInform. 41
New methodology for the protecting-group-free synthesis of primary amines is presented. By optimizing the metal hydride/ammonia mediated reductive amination of aldehydes and hemiacetals, primary amines were selectively prepared with no or minimal for
Autor:
Emma M. Dangerfield, Gregory W. Haslett, Anna L. Win-Mason, Mattie S. M. Timmer, Bridget L. Stocker
Publikováno v:
ChemInform. 41
As noted inhibitors of glycosidases, iminosugars have enormous therapeutic potential in the treatment of a number of diseases such as cancer, diabetes, and lysosomal storage disorders. Accordingly, much effort has been expended over the past decades
Autor:
Anna L. Win, Lars Kröger, Ruth Falshaw, Joachim Thiem, Erzsébet Farkas, Andrew Falshaw, Joanne B. Hart
Publikováno v:
Carbohydrate research. 339(11)
The products from the enzymatic β- d -galactopyranosylation of 1 d - chiro -inositol, 1 d -pinitol, 1 d -3- O -allyl-4- O -methyl- chiro -inositol, 1 d -3,4-di- O -methyl- chiro -inositol, 1 l - chiro -inositol and myo -inositol in combined yields r