Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Anna L. Stratford"'
Autor:
Sandra E. Dunn, Michael Pollak, Marco Gottardis, Joan Carboni, Robert I. Nicholson, Helen E. Jones, Pauline Finlay, Julia M.W. Gee, Eugene Park, Anna L. Stratford, Michelle Y.C. Wang, Hamid Masoudi, Kaiji Hu, Golareh Habibi, Jennifer H. Law
Supplementary Figure 1 from Phosphorylated Insulin-Like Growth Factor-I/Insulin Receptor Is Present in All Breast Cancer Subtypes and Is Related to Poor Survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed96153bfbcc226a63b1ca283392dc9
https://doi.org/10.1158/0008-5472.22375809.v1
https://doi.org/10.1158/0008-5472.22375809.v1
Autor:
Sandra E. Dunn, Connie J. Eaves, Hans-Dieter Royer, Isabelle M. Berquin, Pauline Johnson, Afshin Raouf, Anna L. Stratford, Lawrence Lee, Alastair H. Davies, Arezoo Astanehe, Jing Wang, Kaiji Hu, Jennifer H. Law, Kristen M. Reipas, Abbas Fotovati, Karen To
Supplementary Methods and Materials, Figures 1-6 from Y-Box Binding Protein-1 Induces the Expression of CD44 and CD49f Leading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82df214052211b4407e274eea205de
https://doi.org/10.1158/0008-5472.22386402.v1
https://doi.org/10.1158/0008-5472.22386402.v1
Autor:
Kristen Reipas, Sandra E. Dunn, Natalie S. Firmino, Anna L. Stratford, Rachel Berns, Kaiji Hu, Alastair H. Davies
Publikováno v:
Oncotarget
The triple-negative breast cancer (TNBC) subtype is enriched in cancer stem cells (CSCs) and clinically correlated with the highest rate of recurrence. Several studies implicate the RSK pathway as being pivotal for the growth and proliferation of CSC
Autor:
Anna L. Stratford, Rachel Berns, Abbas Fotovati, Kaiji Hu, Arezoo Astanehe, Christopher A. Maxwell, Sandra E. Dunn, Kristen Reipas, Natalie S. Firmino, Mary Rose Pambid, Alastair H. Davies, Gordon B. Mills
Publikováno v:
Stem Cells. 32:1437-1450
There is growing evidence that cancer-initiation could result from epigenetic changes. Y-box binding protein-1 (YB-1) is a transcription/translation factor that promotes the formation of tumors in transgenic mice; however, the underlying molecular ev
Autor:
Martin L, Read, Robert I, Seed, Bhavika, Modasia, Perkin P K, Kwan, Neil, Sharma, Vicki E, Smith, Rachel J, Watkins, Sukhchain, Bansal, Teresa, Gagliano, Anna L, Stratford, Tariq, Ismail, Michael J O, Wakelam, Dae S, Kim, Stephen T, Ward, Kristien, Boelaert, Jayne A, Franklyn, Andrew S, Turnell, Christopher J, McCabe
The PTTG1-binding factor (PBF) is a transforming gene capable of eliciting tumor formation in xenograft models. However, the precise role of PBF in tumorigenesis and its prognostic value as a cancer biomarker remain largely uncharacterised, particula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fe48c4cd61b4075668f3bbbecbd7d4cc
http://hdl.handle.net/11392/2279614
http://hdl.handle.net/11392/2279614
Autor:
Abbas Fotovati, Kaiji Hu, Mandeep Takhar, Sandra E. Dunn, Anna L. Stratford, Annette Lasham, Peter H. Watson, Rachel Brough, Kristen Reipas, Cristin G. Print, Jessica Frankum, Christopher J. Lord, Alan Ashworth
Publikováno v:
Stem Cells. 30:1338-1348
Y-box binding protein-1 (YB-1) is the first reported oncogenic transcription factor to induce the tumor-initiating cell (TIC) surface marker CD44 in triple-negative breast cancer (TNBC) cells. In order for CD44 to be induced, YB-1 must be phosphoryla
Autor:
Kaiji Hu, Anna L. Stratford, Alastair H. Davies, Sandra E. Dunn, Steven Pelech, Philip Hieter, Isabelle M. Berquin, Spencer A. Freeman, Mary Rose Pambid, I. J. Barrett, Christopher A. Maxwell
Publikováno v:
Oncogene
Y-box binding protein-1 (YB-1) expression in the mammary gland promotes breast carcinoma that demonstrates a high degree of genomic instability. In the present study, we developed a model of pre-malignancy to characterize the role of this gene during
Autor:
Jing Wang, Connie J. Eaves, Lawrence K. Lee, Jennifer Law, Kristen Reipas, Sandra E. Dunn, Pauline Johnson, Anna L. Stratford, Isabelle M. Berquin, Afshin Raouf, Karen To, Alastair H. Davies, Abbas Fotovati, Hans-Dieter Royer, Arezoo Astanehe, Kaiji Hu
Publikováno v:
Cancer Research. 70:2840-2851
Y-box binding protein-1 (YB-1) is an oncogenic transcription/translation factor expressed in >40% of breast cancers, where it is associated with poor prognosis, disease recurrence, and drug resistance. We questioned whether this may be linked to the
Autor:
Wan L. Lam, Vincent Duronio, Anna L. Stratford, Arezoo Astanehe, Isabelle M. Berquin, Sandra E. Dunn, M R Finkbeiner, Ashleen Shadeo, Abbas Fotovati, Karen To, Payman Hojabrpour
Publikováno v:
Oncogene. 28:2406-2418
PIK3CA, which codes for the p110alpha catalytic subunit of phosphatidylinositol-3-kinase (PI3K), is implicated as an oncogene. Despite importance of PIK3CA in cancer, little is known about what drives up its expression in tumor cells. We recently cha
Autor:
Arezoo Astanehe, Anna L. Stratford, M R Finkbeiner, Helen Jiang, Ashleen Shadeo, Abbas Fotovati, Peter Eirew, Peter R. Mertens, Afshin Raouf, Sandra E. Dunn, Yongjun Zhao, Connie J. Eaves, Alastair H. Davies, Paolo M. Comoglio, Karen To, Carla Boccaccio
Publikováno v:
Oncogene; Vol 28
Oncogene
Oncogene
Basal-like breast cancers (BLBCs) are aggressive tumors with high relapse rates and poor survival. We recently reported that >70% of primary BLBCs express the oncogenic transcription/translation factor Y-box binding protein-1 (YB-1) and silencing it