Protection against oxaliplatin-induced mechanical and thermal hypersensitivity in Sarm1

Autor: Erzsébet Pór, Matthew White, Michael P. Coleman, Anna L. Wilbrey, Stacey Anne Gould, Robert Adalbert

Publikováno v: Experimental neurology. 338

Chemotherapy-induced peripheral neuropathy (CIPN) is a common dose-limiting side effect of cancer treatment, often associated with degeneration of sensory axons or their terminal regions. Presence of the slow Wallerian degeneration protein (WLDS), or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b49718dc7a52cae2a700eecc4c66cf20
https://pubmed.ncbi.nlm.nih.gov/33460644

WldS protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice

Autor: Armando A. Genazzani, Michele Di Stefano, Elisabetta Babetto, Lucie Janeckova, Bogdan Beirowski, Richard A. Billington, Smith Trevor Stanley, Michael P. Coleman, Robert Hartley, Anna L. Wilbrey, Laura Conforti, Giulio Magni, Robert Adalbert, Francesca Mazzola, Giacomo Morreale, Jonathan Gilley, Richard R. Ribchester

Publikováno v: Conforti, L, Wilbrey, A, Morreale, G, Janeckova, L, Beirowski, B, Adalbert, R, Mazzola, F, Di Stefano, M, Hartley, R, Babetto, E, Smith, T, Gilley, J, Billington, R A, Genazzani, A A, Ribchester, R R, Magini, G & Coleman, M P 2009, ' Wld(S) protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice ', Journal of Cell Biology, vol. 184, no. 4, pp. 491-500 . https://doi.org/10.1083/jcb.200807175
The Journal of Cell Biology

The slow Wallerian degeneration (WldS) protein protects injured axons from degeneration. This unusual chimeric protein fuses a 70–amino acid N-terminal sequence from the Ube4b multiubiquitination factor with the nicotinamide adenine dinucleotide–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb4a668fcd796d891a201c423997493
https://doi.org/10.1083/jcb.200807175

Evolutionary divergence of valosin-containing protein/cell division cycle protein 48 binding interactions among endoplasmic reticulum-associated degradation proteins

Autor: Giacomo, Morreale, Laura, Conforti, John, Coadwell, Anna L, Wilbrey, Michael P, Coleman

Publikováno v: The FEBS journal. 276(5)

Endoplasmic reticulum (ER)-associated degradation (ERAD) is a cell-autonomous process that eliminates large quantities of misfolded, newly synthesized protein, and is thus essential for the survival of any basic eukaryotic cell. Accordingly, the prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4f42e93d4c894891981300f9c8ac3dd3
https://pubmed.ncbi.nlm.nih.gov/19175675

Transcriptional regulatory network for sexual differentiation in fission yeast

Autor: Anna L. Wilbrey, Jürg Bähler, Juan Mata

Publikováno v: Genome Biology

Microarray analysis of the transcriptome of fission yeast after genetic perturbation of 6 genes known to have a role in sexual differentiation reveals insights into the regulatory principles controlling the gene expression program driving this proces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0977454b940b75b9ad4b0e419e90dce9
http://europepmc.org/articles/PMC2246291