Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Anna Kruschinski"'
Autor:
Aldo M. Roccaro, Antonio Sacco, Werner G. Purschke, Michele Moschetta, Klaus Buchner, Christian Maasch, Dirk Zboralski, Stefan Zöllner, Stefan Vonhoff, Yuji Mishima, Patricia Maiso, Michaela R. Reagan, Silvia Lonardi, Marco Ungari, Fabio Facchetti, Dirk Eulberg, Anna Kruschinski, Axel Vater, Giuseppe Rossi, Sven Klussmann, Irene M. Ghobrial
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 118-128 (2014)
Summary: Bone marrow (BM) metastasis remains one of the main causes of death associated with solid tumors as well as multiple myeloma (MM). Targeting the BM niche to prevent or modulate metastasis has not been successful to date. Here, we show that s
Externí odkaz:
https://doaj.org/article/8703a09514fb42bea775ea363251cffb
Autor:
Jehad Charo, Thomas Blankenstein, Hinrich Abken, Markus Chmielewski, Anna Kruschinski, Cynthia Perez, Lara Le Wührmann, Joanna J. Listopad, Ana Textor
Schematic representation of species-specific molecular interactions in models of CAR-mediated tumor rejection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8249a48a7fe3c64233d8f5c601e0d7c
https://doi.org/10.1158/0008-5472.22403057.v1
https://doi.org/10.1158/0008-5472.22403057.v1
Autor:
Jehad Charo, Thomas Blankenstein, Hinrich Abken, Markus Chmielewski, Anna Kruschinski, Cynthia Perez, Lara Le Wührmann, Joanna J. Listopad, Ana Textor
Supplementary Figure Legends (1-5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff255479445337f3e9e35ea81513bf7
https://doi.org/10.1158/0008-5472.22403060
https://doi.org/10.1158/0008-5472.22403060
Autor:
Ellen Weisberg, James D. Griffin, Paul W. Manley, Abdel Kareem Azab, Dirk Eulberg, Richard Stone, Anna Kruschinski, Martin Sattler
Publikováno v:
Oncotarget
Resistance to targeted tyrosine kinase inhibitors (TKI) remains a challenge for the treatment of myeloid leukemias. Following treatment with TKIs, the bone marrow microenvironment has been found to harbor a small pool of surviving leukemic CD34+ prog
Publikováno v:
Enzmann, Volker; Lecaudé, Stéphanie; Kruschinski, Anna; Vater, Axel (2017). CXCL12/SDF-1-Dependent Retinal Migration of Endogenous Bone Marrow-Derived Stem Cells Improves Visual Function after Pharmacologically Induced Retinal Degeneration. Stem cell reviews and reports, 13(2), pp. 278-286. Springer 10.1007/s12015-016-9706-0
Mobilized bone marrow-derived stem cells (BMSC) have been discussed as an alternative strategy for endogenous repair. Thereby, different approaches for BMSC mobilization have been pursued. Herein, the role of a newly discovered oligonucleotide for re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61b2d7f1a286995e4fd0bcd9fc7f5d4
Autor:
Anna Kruschinski, Michael J. Keating, William G. Wierda, Dirk Zboralski, Jan A. Burger, Nathalie Y. Rosin, Christian Maasch, Julia Hoellenriegel
Publikováno v:
Blood. 123:1032-1039
The CXC chemokine ligand (CXCL12, or stromal cell-derived factor-1 as previously known) plays a critical role for homing and retention of chronic lymphocytic leukemia (CLL) cells in tissues such as the bone marrow (BM). In tissues, stromal cells cons
Autor:
Thomas Blankenstein, Lara Le Wührmann, Markus Chmielewski, Anna Kruschinski, Joanna Listopad, Hinrich Abken, Cynthia Perez, Ana Textor, Jehad Charo
Publikováno v:
Cancer research. 74(23)
Adoptive T-cell therapy using chimeric antigen receptor–modified T cells (CAR-T therapy) has shown dramatic efficacy in patients with circulating lymphoma. However, eradication of solid tumors with CAR-T therapy has not been reported yet to be effi
Publikováno v:
Blood. 128:3021-3021
Hematological malignancies are characterized by the expansion of malignant cells in the peripheral blood and in stroma-rich niches such as the bone marrow or lymphoid tissues. Anti-CD20 monoclonal antibodies (mAbs) are highly effective in eliminating
Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats
Autor:
Sven Klussmann, Frederick M. Lartey, Reem Alomran, Taichang Jang, J. Martin Brown, Dirk Zboralski, Lawrence Recht, Stefan Zöllner, Milton Merchant, Anna Kruschinski, Sophia B. Chernikova, Shie-Chau Liu, Jason Stafford
Publikováno v:
Neuro-oncology. 16(1)
Tumor irradiation blocks local angiogenesis, forcing any recurrent tumor to form new vessels from circulating cells. We have previously demonstrated that the post-irradiation recurrence of human glioblastomas in the brains of nude mice can be delayed
Autor:
Werner Purschke, Axel Vater, D Vossmeyer, Stefan Vonhoff, Sven Klussmann, M Lioznov, Klaus Buchner, Christian Maasch, Frank Schwoebel, K Hübel, M Humphrey, Anna Kruschinski, Stefan Zöllner, N Kröger, J Sahlmann, Frank Fliegert
Publikováno v:
Clinical pharmacology and therapeutics. 94(1)
NOX-A12 is a PEGylated mirror-image oligonucleotide (a so-called Spiegelmer) that binds to CXCL12 (stromal cell–derived factor-1, SDF-1) with high affinity thereby inhibiting CXCL12 signaling on both its receptors, CXCR4 and CXCR7. In animals, NOX-