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Publikováno v:
Scopus-Elsevier
The method of delivering a therapeutic gene into a patient is still one of the major obstacles towards successful human gene therapy. Here we describe a novel gene delivery approach using TheraCyte immunoisolation devices. Retroviral vector producing
Autor:
Klaus Cichutek, Roger J. Pomerantz, Zahida Parveen, Anna Krupetsky, Ralph Dornburg, Martin Engelstädter
Publikováno v:
Nature Biotechnology. 18:623-629
Gene therapy applications of retroviral vectors derived from C-type retroviruses have been limited to introducing genes into dividing target cells. Here, we report genetically engineered C-type retroviral vectors derived from spleen necrosis virus (S