Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Anna Krilova"'
Autor:
Magdalena Jadwiga Utsch, Anna Krilova, Özlem Türeci, Martin Schuler, Karl Dhaene, Markus Jerling, Christoph Rohde, Stefan Bauer, Tobias Dechow, Ugur Sahin, Heike Richly, Christoph Huber
Introduction IMAB362 (Zolbetuximab) is a chimeric monoclonal antibody that binds to Claudin-18.2, a target antigen specific to cancer cells. In vitro, IMAB362 mediates cell death through antibody-dependent cellular cytotoxicity and complement-depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb9949f013111d7e7dd98d889459c98
https://doi.org/10.1016/j.ejca.2018.05.007
https://doi.org/10.1016/j.ejca.2018.05.007
Autor:
Janis Eglitis, Laima Tihomirova, Guntars Keire, Anna Krilova, Mihails Timofejevs, Marcis Leja, Olga Sinicka, Janis Petrevics, Iveta Vaivade, Oksana Fokina, Ilona Mandrika, Raitis Peculis, Aivars Stengrevics
Publikováno v:
Advances in Medical Sciences. 59:114-119
Purpose In this report, we summarise data on BRCA1 gene analysis in Latvia to characterise criteria of genetic testing for breast and ovarian cancer susceptibility. Material/methods Analysis by SSCP/HD, MALDI-TOF mass spectrometry or DNA sequencing w
Autor:
Ulrike Helbig, Tanja Trarbach, Henning Schulze-Bergkamen, Christian Mueller, Salah-Eddin Al-Batran, Anna Krilova, Peter C. Thuss-Patience, Ugur Sahin, Ö. Türeci, Zanete Zvirbule, Karsten Schulmann, Christoph Huber, Florian Lordick, Goetz von Wichert, Stefan Bauer, Martin Schuler
4080 Background: IMAB362 is a monoclonal antibody targeting isoform 2 of the tight junction component claudin 18 (CLDN18.2), a tumor-selective antigen frequently expressed in several types of epithelial adenocarcinomas. Preclinically, IMAB362 exerts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943006c643664b5b690f871d9dfb90f8
Autor:
Volker Brass, Peter C. Thuss-Patience, Ö. Türeci, Marianne Just, Salah-Eddin Al-Batran, Florian Lordick, Michael Bitzer, Wael Hozaeel, Jens Freiberg-Richter, Ugur Sahin, Zanete Zvirbule, Christian Mueller, Anna Krilova, Elmar Daalman
Publikováno v:
Journal of Clinical Oncology. 33:e15079-e15079
e15079 Background: IMAB362 is the first-in-class monoclonal antibody against the tight junction molecule claudin 18.2 (CLDN18.2) executing its antitumor activity via 4 highly potent modes of action...