Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Anna Kreshuk"'
Autor:
Marc Cicero Schubert, Stella Judith Soyka, Amr Tamimi, Emanuel Maus, Julian Schroers, Niklas Wißmann, Ekin Reyhan, Svenja Kristin Tetzlaff, Yvonne Yang, Robert Denninger, Robin Peretzke, Carlo Beretta, Michael Drumm, Alina Heuer, Verena Buchert, Alicia Steffens, Jordain Walshon, Kathleen McCortney, Sabine Heiland, Martin Bendszus, Peter Neher, Anna Golebiewska, Wolfgang Wick, Frank Winkler, Michael O. Breckwoldt, Anna Kreshuk, Thomas Kuner, Craig Horbinski, Felix Tobias Kurz, Robert Prevedel, Varun Venkataramani
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Intravital 2P-microscopy enables the longitudinal study of brain tumor biology in superficial mouse cortex layers. Intravital microscopy of the white matter, an important route of glioblastoma invasion and recurrence, has not been feasible,
Externí odkaz:
https://doaj.org/article/5aab522dd6b7443baef320c1b7f67875
Autor:
Nuno Sartingen, Vanessa Stürmer, Matthias Kaltenböck, Thorsten G. Müller, Paul Schnitzler, Anna Kreshuk, Hans-Georg Kräusslich, Uta Merle, Frauke Mücksch, Barbara Müller, Constantin Pape, Vibor Laketa
Publikováno v:
Viruses, Vol 16, Iss 9, p 1473 (2024)
The emergence of novel pathogens, exemplified recently by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), highlights the need for rapidly deployable and adaptable diagnostic assays to assess their impact on human health and guide pu
Externí odkaz:
https://doaj.org/article/324664c9fd4240c2a09a61a28ee13b7b
Autor:
Ewa Sitarska, Silvia Dias Almeida, Marianne Sandvold Beckwith, Julian Stopp, Jakub Czuchnowski, Marc Siggel, Rita Roessner, Aline Tschanz, Christer Ejsing, Yannick Schwab, Jan Kosinski, Michael Sixt, Anna Kreshuk, Anna Erzberger, Alba Diz-Muñoz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract To navigate through diverse tissues, migrating cells must balance persistent self-propelled motion with adaptive behaviors to circumvent obstacles. We identify a curvature-sensing mechanism underlying obstacle evasion in immune-like cells. S
Externí odkaz:
https://doaj.org/article/505ca1c735d5448bb63418ff9ca18075
Publikováno v:
eLife, Vol 12 (2023)
Electron microscopy (EM) provides a uniquely detailed view of cellular morphology, including organelles and fine subcellular ultrastructure. While the acquisition and (semi-)automatic segmentation of multicellular EM volumes are now becoming routine,
Externí odkaz:
https://doaj.org/article/adb0e85e3fec468eb694ee3b8bcd5cab
Publikováno v:
Frontiers in Computer Science, Vol 4 (2022)
The remarkable performance of Convolutional Neural Networks on image segmentation tasks comes at the cost of a large amount of pixelwise annotated images that have to be segmented for training. In contrast, feature-based learning methods, such as the
Externí odkaz:
https://doaj.org/article/a2a3d32ebc8e4b608d7e42062a27390b
Autor:
Florian Levet, Anne E. Carpenter, Kevin W. Eliceiri, Anna Kreshuk, Peter Bankhead, Robert Haase
Publikováno v:
F1000Research, Vol 10 (2021)
Fast-paced innovations in imaging have resulted in single systems producing exponential amounts of data to be analyzed. Computational methods developed in computer science labs have proven to be crucial for analyzing these data in an unbiased and eff
Externí odkaz:
https://doaj.org/article/20d7a60b0c774f80a4faa2418554647a
Autor:
Athul Vijayan, Rachele Tofanelli, Sören Strauss, Lorenzo Cerrone, Adrian Wolny, Joanna Strohmeier, Anna Kreshuk, Fred A Hamprecht, Richard S Smith, Kay Schneitz
Publikováno v:
eLife, Vol 10 (2021)
A fundamental question in biology is how morphogenesis integrates the multitude of processes that act at different scales, ranging from the molecular control of gene expression to cellular coordination in a tissue. Using machine-learning-based digita
Externí odkaz:
https://doaj.org/article/0fd1977745b34159b5e061a2a61c266c
Autor:
Adrian Wolny, Lorenzo Cerrone, Athul Vijayan, Rachele Tofanelli, Amaya Vilches Barro, Marion Louveaux, Christian Wenzl, Sören Strauss, David Wilson-Sánchez, Rena Lymbouridou, Susanne S Steigleder, Constantin Pape, Alberto Bailoni, Salva Duran-Nebreda, George W Bassel, Jan U Lohmann, Miltos Tsiantis, Fred A Hamprecht, Kay Schneitz, Alexis Maizel, Anna Kreshuk
Publikováno v:
eLife, Vol 9 (2020)
Quantitative analysis of plant and animal morphogenesis requires accurate segmentation of individual cells in volumetric images of growing organs. In the last years, deep learning has provided robust automated algorithms that approach human performan
Externí odkaz:
https://doaj.org/article/5ee716dde0d6486db0090c254fa1bb18
Autor:
Sharon C. Yates, Nicolaas E. Groeneboom, Christopher Coello, Stefan F. Lichtenthaler, Peer-Hendrik Kuhn, Hans-Ulrich Demuth, Maike Hartlage-Rübsamen, Steffen Roßner, Trygve Leergaard, Anna Kreshuk, Maja A. Puchades, Jan G. Bjaalie
Publikováno v:
Frontiers in Neuroinformatics, Vol 13 (2019)
Transgenic animal models are invaluable research tools for elucidating the pathways and mechanisms involved in the development of neurodegenerative diseases. Mechanistic clues can be revealed by applying labelling techniques such as immunohistochemis
Externí odkaz:
https://doaj.org/article/5dc24db4c0df4d0ba8ee4846c5996928
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87351 (2014)
We describe a method for fully automated detection of chemical synapses in serial electron microscopy images with highly anisotropic axial and lateral resolution, such as images taken on transmission electron microscopes. Our pipeline starts from cla
Externí odkaz:
https://doaj.org/article/1c590700cce443c79777a31832570226