Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna Klucnika"'
Autor:
Ason C. Y. Chiang, Jan Ježek, Peiqiang Mu, Ying Di, Anna Klucnika, Martin Jabůrek, Petr Ježek, Hansong Ma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Genetic screens have been used extensively to probe interactions between nuclear genes and their impact on phenotypes. Probing interactions between mitochondrial genes and their phenotypic outcome, however, has not been possible due to a lac
Externí odkaz:
https://doaj.org/article/535c6d0b32ad4ccfa77fbdd9ef88c699
Autor:
Anna Klucnika, Hansong Ma
Publikováno v:
Open Biology, Vol 9, Iss 3 (2019)
The mitochondrial genome is an evolutionarily persistent and cooperative component of metazoan cells that contributes to energy production and many other cellular processes. Despite sharing the same host as the nuclear genome, the multi-copy mitochon
Externí odkaz:
https://doaj.org/article/86fe0232c4ac4a0594e8a6e0bfec6d23
Autor:
Anna Klucnika, Peiqiang Mu, Jan Jezek, Matthew McCormack, Ying Di, Charles R. Bradshaw, Hansong Ma
Funder: Gurdon Institute Core Facility
Mechanisms that safeguard mitochondrial DNA (mtDNA) limit the accumulation of mutations linked to mitochondrial and age-related diseases. Yet, pathways that repair double-strand breaks (DSBs) in animal mito
Mechanisms that safeguard mitochondrial DNA (mtDNA) limit the accumulation of mutations linked to mitochondrial and age-related diseases. Yet, pathways that repair double-strand breaks (DSBs) in animal mito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1de1cb52ef72575674f9c2b29b1d15
https://www.repository.cam.ac.uk/handle/1810/344209
https://www.repository.cam.ac.uk/handle/1810/344209
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 16, Iss 12, p e1008948 (2020)
PLoS Genetics, Vol 16, Iss 12, p e1008948 (2020)
During metazoan development, the cell cycle is remodelled to coordinate proliferation with differentiation. Developmental cues cause dramatic changes in the number and timing of replication initiation events, but the mechanisms and physiological impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec8dd416c0d686fa0d4618cca7a7a3a
During metazoan development, the cell cycle is remodelled to coordinate proliferation with differentiation. Developmental cues cause dramatic changes in the number and timing of replication initiation events, but the mechanisms and physiological impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39544a08313a4633d54102d475af2d25
https://doi.org/10.1101/2020.06.24.168708
https://doi.org/10.1101/2020.06.24.168708
Autor:
Hansong Ma, Anna Klucnika
Publikováno v:
Open Biology
Open Biology, Vol 9, Iss 3 (2019)
Open Biology, Vol 9, Iss 3 (2019)
The mitochondrial genome is an evolutionarily persistent and cooperative component of metazoan cells that contributes to energy production and many other cellular processes. Despite sharing the same host as the nuclear genome, the multi-copy mitochon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3764ca4351cde0d4bfd61f723b1e8343
https://www.repository.cam.ac.uk/handle/1810/291030
https://www.repository.cam.ac.uk/handle/1810/291030
Autor:
Anna Klucnika, Hansong Ma
Publikováno v:
Philos Trans R Soc Lond B Biol Sci
The animal mitochondrial genome, although small, can have a big impact on health and disease. Non-pathogenic sequence variation among mitochondrial DNA (mtDNA) haplotypes influences traits including fertility, healthspan and lifespan, whereas pathoge