CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice

Autor: Torben Sølbeck Rasmussen, Anna Kirstine Koefoed, Ling Deng, Musemma K. Muhammed, Geneviève M. Rousseau, Witold Kot, Sabrina Sprotte, Horst Neve, Charles M.A.P. Franz, Axel Kornerup Hansen, Finn Kvist Vogensen, Sylvain Moineau, Dennis Sandris Nielsen

Publikováno v: Rasmussen, T S, Koefoed, A K, Deng, L, Muhammed, M K, Rousseau, G M, Kot, W, Sprotte, S, Neve, H, Franz, C M A P, Hansen, A K, Vogensen, F K, Moineau, S & Nielsen, D S 2023, ' CRISPR-Cas provides limited phage immunity to a prevalent gut bacterium in gnotobiotic mice ', ISME Journal, vol. 17, pp. 432–442 . https://doi.org/10.1038/s41396-023-01358-4

Many prokaryotes harbor the adaptive CRISPR-Cas system, which stores small nucleotide fragments from previous invasions of nucleic acids via viruses or plasmids. This molecular archive blocks further invaders carrying identical or similar nucleotide

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https://curis.ku.dk/portal/da/publications/crisprcas-provides-limited-phage-immunity-to-a-prevalent-gut-bacterium-in-gnotobiotic-mice(44314f1b-810e-4360-80ea-c46333aef11c).html