Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Anna Kirstein"'
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Akademický článek
A new human adipocyte model with PTEN haploinsufficiency
Autor: Franziska Kässner, Anna Kirstein, Norman Händel, Gordian L. Schmid, Kathrin Landgraf, Antje Berthold, Astrid Tannert, Michael Schaefer, Martin Wabitsch, Wieland Kiess, Antje Körner, Antje Garten
Publikováno v: Adipocyte, Vol 9, Iss 1, Pp 290-301 (2020)
Few human cell strains are suitable and readily available as in vitro adipocyte models. We used resected lipoma tissue from a patient with germline phosphatase and tensin homolog (PTEN) haploinsufficiency to establish a preadipocyte cell strain terme
Externí odkaz: https://doaj.org/article/708df9101bfa40b88a6eea31fcb2ba08
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3
PTEN regulates adipocyte progenitor growth, differentiation and replicative aging
Autor: Wieland Kiess, Peter Kovacs, Kathrin Landgraf, Antje Körner, Jana Breitfeld, Antje Garten, Stephanie Kehr, Judith Lorenz, Peter F. Stadler, Michèle Nebe, Anna Kirstein, Martha Hanschkow, Diana Le Duc, Melanie Penke
The tumor suppressor phosphatase and tensin homolog (PTEN) negatively regulates the insulin signaling pathway. Germline PTEN pathogenic variants cause PTEN Hamartoma Tumor Syndrome (PHTS), associated with lipoma development in children. It remains un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7166637dff47eb85ea09ad8571b69aff
https://doi.org/10.1101/2021.01.05.425433
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4
Lomeguatrib Increases the Radiosensitivity of MGMT Unmethylated Human Glioblastoma Multiforme Cell Lines
Autor: Thomas E. Schmid, Anna Kirstein, Daniela Schilling, Stephanie E. Combs
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 13
International Journal of Molecular Sciences, Vol 22, Iss 6781, p 6781 (2021)
Int. J. Mol. Sci. 22:6781 (2021)
Background: Treatment resistance of glioblastoma multiforme to chemo- and radiotherapy remains a challenge yet to overcome. In particular, the O6-methylguanine-DNA-methyltransferase (MGMT) promoter unmethylated patients have only little benefit from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c60e88cb8bc87aa096cde81c783d212
https://mediatum.ub.tum.de/1689343
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6
Obesity–An Update on the Basic Pathophysiology and Review of Recent Therapeutic Advances
Autor: Erind Gjermeni, Ulrich Laufs, Diana Le Duc, Matthias Blüher, Antje Garten, Linnaeus Bundalian, Anna Kirstein, Michael Kirchhof, Florentien Kolbig, Julius L. Katzmann
Publikováno v: Biomolecules 11:1426 (2021)
Biomolecules
Biomolecules, Vol 11, Iss 1426, p 1426 (2021)
Obesity represents a major public health problem with a prevalence increasing at an alarming rate worldwide. Continuous intensive efforts to elucidate the complex pathophysiology and improve clinical management have led to a better understanding of b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fedad05f4d760bb82a613234473f2e1
https://doi.org/10.3390/biom11101426
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8
Stereotactic irradiation of the resection cavity after surgical resection of brain metastases - when is the right timing?
Autor: Kerstin A. Kessel, Sophia Scharl, Bernhard Meyer, Claus Zimmer, Markus Oechsner, Christian Diehl, Anna Kirstein, Christoph Straube, Stephanie E. Combs
Publikováno v: Acta Oncol. 58, 1714-1719 (2019)
Publons
Purpose: This study aimed to evaluate whether an early beginning of the adjuvant stereotactic radiotherapy after macroscopic complete resection of 1-3 brain metastases is essential or whether longer intervals between surgery and radiotherapy are feas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cafcca9c837e09b9e38cf8cbd03178ca
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=56699
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9
The Role of miRNA for the Treatment of MGMT Unmethylated Glioblastoma Multiforme
Autor: Stephanie E. Combs, Thomas E. Schmid, Anna Kirstein
Publikováno v: Cancers 12:1099 (2020)
Cancers, Vol 12, Iss 1099, p 1099 (2020)
Cancers
Glioblastoma multiforme (GBM) is the most common high-grade intracranial tumor in adults. It is characterized by uncontrolled proliferation, diffuse infiltration due to high invasive and migratory capacities, as well as intense resistance to chemo- a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb6dd074a8105fcbcda0ba16ff5ae9d
https://doi.org/10.3390/cancers12051099
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10
Cavity volume changes after surgery of a brain metastasis-consequences for stereotactic radiation therapy
Autor: Anna Kirstein, Christoph Straube, Marciana-Nona Duma, Kerstin A. Kessel, Sophia Scharl, Markus Oechsner, Stephanie E. Combs
Publikováno v: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 195(3)
For a large or symptomatic brain metastasis, resection and adjuvant radiotherapy are recommended. Hypofractionated stereotactic radiotherapy (HFSRT) is increasingly applied in patients with a limited number of lesions. Exact target volume definition
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91af9403791bcf58d797cc504ec5bcad
https://pubmed.ncbi.nlm.nih.gov/30386864
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