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Autor:
Andrew Muranyi, Tobias Ammer, Anna Kechter, Vijay P. S. Rawat, Amit Sinha, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Anca Azoitei, Cagatay Günes, Annalisa Mupo, George Vassiliou, Shiva Bamezai, Christian Buske
Publikováno v:
Blood Advances. 7:351-364
NPM1 is among the most frequently mutated genes in acute myeloid leukemia (AML). Mutations in the NPM1 gene result in the increased export of NPM1 to the cytoplasm (NPM1c) and are associated with multiple transforming events including the aberrant up