Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Anna Karin Gertrud Linnea Belfrage"'
Autor:
Per-Ola Johansson, Katarina Jansson, Lotta Vrang, Yantao Chen, Anna Karin Gertrud Linnea Belfrage, Anders Hallberg, Bertil Samuelsson, Åsa Rosenquist, Ingemar Kvarnström, Elizabeth Hamelink, Michael J. Blackman
Publikováno v:
Journal of Medicinal Chemistry. 47:3353-3366
Picomolar to low nanomolar inhibitors of the two aspartic proteases plasmepsin (Plm) I and II, from the malaria parasite Plasmodium falciparum, have been identified from sets of libraries containing novel statine-like templates modified at the amino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad85ebf0ea8227fc3c032bdf548cf28f
https://doi.org/10.1021/jm031106i
https://doi.org/10.1021/jm031106i
Autor:
Kenneth Alan Simmen, Tatiana Agback, Michael Pelcman, Herman de Kock, Horst Wähling, Christina Rydegård, Joseph A. Martin, Magnus Nilsson, Pierre Raboisson, Pedro Pinho, Xiao Xiong Zhou, Anna Winqvist, Kurt Benckestock, David Bernard Smith, Mirva Boothee, Christian Sund, Bertil Samuelsson, Lotta Vrang, Åsa Rosenquist, Nils Gunnar Johansson, Anna Karin Gertrud Linnea Belfrage, Sophie Lachau-Durand, Klaus Klumpp, Koen Vandyck, Kristina Wikström, Ylva Terelius, Tim H. M. Jonckers, Tse-I Lin, Genadiy Kalayanov, Anneli Lindqvist
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(9)
4′-Azido-2′-deoxy-2′-methylcytidine ( 14 ) is a potent nucleoside inhibitor of the HCV NS5B RNA-dependent RNA polymerase, displaying an EC 50 value of 1.2 μM and showing moderate in vivo bioavailability in rat ( F = 14%). Here we describe the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a6344324a04d52d6f4b63ee7042cac
https://pubmed.ncbi.nlm.nih.gov/22472694
https://pubmed.ncbi.nlm.nih.gov/22472694