Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anna Kaffke"'
Autor:
Jonas Engesser, Robin Khatri, Darius P. Schaub, Yu Zhao, Hans-Joachim Paust, Zeba Sultana, Nariaki Asada, Jan-Hendrik Riedel, Varshi Sivayoganathan, Anett Peters, Anna Kaffke, Saskia-Larissa Jauch-Speer, Thiago Goldbeck-Strieder, Victor G. Puelles, Ulrich O. Wenzel, Oliver M. Steinmetz, Elion Hoxha, Jan-Eric Turner, Hans-Willi Mittrücker, Thorsten Wiech, Tobias B. Huber, Stefan Bonn, Christian F. Krebs, Ulf Panzer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a life-threatening autoimmune disease that often results in kidney failure caused by crescentic glomerulonephritis (GN). To date, treatment of most patients with ANCA-GN r
Externí odkaz:
https://doaj.org/article/287d8b69dd7e4d95bc28f18d29e2859c
Autor:
Jonas Engesser, Huiying Wang, Sonja Kapffer, Anna Kaffke, Anett Peters, Hans-Joachim Paust, Markus Geissen, Christian F. Krebs, Ulf Panzer, Nariaki Asada
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Th17 cells play crucial roles in host defense and the pathogenesis of autoimmune diseases in the skin. While their differentiation mechanisms have been extensively studied, the origin of skin Th17 cells remains unclear. In this study, we analyzed sin
Externí odkaz:
https://doaj.org/article/76a895509ad0421d869ae51f71b26a09
Autor:
Jan-Hendrik Riedel, Lennart Robben, Hans-Joachim Paust, Yu Zhao, Nariaki Asada, Ning Song, Anett Peters, Anna Kaffke, Alina Borchers, Gisa Tiegs, Larissa Seifert, Nicola M. Tomas, Elion Hoxha, Ulrich O. Wenzel, Tobias B. Huber, Thorsten Wiech, Jan-Eric Turner, Christian F. Krebs, Ulf Panzer
Publikováno v:
JCI Insight, Vol 8, Iss 1 (2023)
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic inflammatory diseases — for example, in different forms of crescentic glomerulonephritis — because of their rapid antiinflammatory effects, low cost, and wide
Externí odkaz:
https://doaj.org/article/6443c52a90ff43ecadb3bda903f06ac0
Autor:
Hans-Joachim Paust, Ning Song, Donatella De Feo, Nariaki Asada, Selma Tuzlak, Yu Zhao, Jan-Hendrik Riedel, Malte Hellmig, Amirrtavarshni Sivayoganathan, Anett Peters, Anna Kaffke, Alina Borchers, Ulrich O. Wenzel, Oliver M. Steinmetz, Gisa Tiegs, Elisabeth Meister, Matthias Mack, Christian Kurts, Sibylle von Vietinghoff, Maja T. Lindenmeyer, Elion Hoxha, Rolf A. K. Stahl, Tobias B. Huber, Stefan Bonn, Catherine Meyer-Schwesinger, Thorsten Wiech, Jan-Eric Turner, Burkhard Becher, Christian F. Krebs, Ulf Panzer
Publikováno v:
Science Translational Medicine. 15
GM-CSF in glomerulonephritis Despite glomerulonephritis being an immune-mediated disease, the contributions of individual immune cell types are not clear. To address this gap in knowledge, Paust et al . characterized pathological immune cells in samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ff737a171d8c56e5892182887e80eb
https://doi.org/10.1126/scitranslmed.add6137
https://doi.org/10.1126/scitranslmed.add6137
Autor:
Jan-Hendrik Riedel, Alina Borchers, Nariaki Asada, Anett Peters, Tilman Schmidt, Ulf Panzer, Pauline Ginsberg, Hans-Joachim Paust, Samuel Huber, Tobias B. Huber, Christian Krebs, Nicola Gagliani, Ning Song, Richard A. Flavell, Anna Kaffke, Jonas Luebbe, Jan-Eric Turner, Lennart Robben, Penelope Pelzcar, Sonja Hiekmann, Christoph Kilian
Publikováno v:
J Am Soc Nephrol
BACKGROUND: IL-17A–producing CD4(+) T helper (T(H)17) cells play a critical role in autoimmune and chronic inflammatory diseases, such as crescentic GN. The proinflammatory effects of IL-17 are mediated by the activation of the IL-17RA/IL-17RC comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b559a2cd1ee4dd27d7cad7fa2b815888
https://doi.org/10.1681/asn.2021030426
https://doi.org/10.1681/asn.2021030426
Autor:
Jan-Hendrik Riedel, Lennart Robben, Hans-Joachim Paust, Yu Zhao, Nariaki Asada, Ning Song, Anett Peters, Anna Kaffke, Alina Borchers, Gisa Tiegs, Larissa Seifert, Nicola M. Tomas, Elion Hoxha, Ulrich O. Wenzel, Tobias B. Huber, Thorsten Wiech, Jan-Eric Turner, Christian F. Krebs, Ulf Panzer
Publikováno v:
JCI insight.
Glucocorticoids remain a cornerstone of therapeutic regimes for autoimmune and chronic inflammatory diseases, for example, in different forms of crescentic glomerulonephritis because of their rapid anti-inflammatory effects, low cost, and wide availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d75733e60b64fb7d63aca69e0484b2
https://pubmed.ncbi.nlm.nih.gov/36355429
https://pubmed.ncbi.nlm.nih.gov/36355429
Autor:
Jasper F. Nies, Anett Peters, Oliver M. Steinmetz, Alina Borchers, Silke R. Brix, Sonja Kapffer, Rolf A.K. Stahl, Tilman Schmidt, Anna Kaffke, Hans-Joachim Paust, Jan-Eric Turner, Sonja Krohn, Jan-Hendrik Riedel, Christian Krebs, Ulf Panzer
Publikováno v:
Journal of the American Society of Nephrology. 29:1210-1222
The IL-17 cytokine family and the cognate receptors thereof have a unique role in organ-specific autoimmunity. Most studies have focused on the founding member of the IL-17 family, IL-17A, as the central mediator of diseases. Indeed, although pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::158ddb074edc113473651fe4fb20493e
https://doi.org/10.1681/asn.2017090949
https://doi.org/10.1681/asn.2017090949
Autor:
Sonja Kapffer, Sabrina B. Bennstein, Friedrich Thaiss, Oliver M. Steinmetz, Anett Peters, Gisa Tiegs, Hans-Willi Mittrücker, Hans-Joachim Paust, Jan-Eric Turner, Silke R. Brix, Ulf Panzer, Christian Krebs, Joachim Velden, Rolf A.K. Stahl, Sonja Krohn, Thorsten Wiech, Anna Kaffke, Claudia Wegscheid, Jan-Hendrik Riedel, Catherine Meyer-Schwesinger
Publikováno v:
Journal of the American Society of Nephrology. 27:1933-1942
Chemokines and chemokine receptors are implicated in regulatory T cell (Treg) trafficking to sites of inflammation and suppression of excessive immune responses in inflammatory and autoimmune diseases; however, the specific requirements for Treg migr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bdbec7134fbdc0de9c8c5658d2431cb
https://doi.org/10.1681/asn.2015020203
https://doi.org/10.1681/asn.2015020203
Autor:
Sabrina B. Bennstein, Rolf A.K. Stahl, Tobias Koyro, Jan-Eric Turner, Joachim Velden, Hans-Joachim Paust, Oliver M. Steinmetz, Ulf Panzer, Anett Peters, Hans-Willi Mittrücker, Stefanie Hünemörder, Anna Kaffke, Tilman Schmidt, Christian Krebs, Friedrich Haag
Publikováno v:
Arthritis & Rheumatology. 67:475-487
Objective The CD4+ T cell immune response plays a pivotal role in the immunopathogenesis of human and experimental lupus nephritis, but the contribution of the Th17/interleukin-17 (IL-17) immune pathway to renal tissue injury in systemic lupus erythe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f07cc622abfc721d20473489376a9e9
https://doi.org/10.1002/art.38955
https://doi.org/10.1002/art.38955
Autor:
Sonja, Krohn, Jasper F, Nies, Sonja, Kapffer, Tilman, Schmidt, Jan-Hendrik, Riedel, Anna, Kaffke, Anett, Peters, Alina, Borchers, Oliver M, Steinmetz, Christian F, Krebs, Jan-Eric, Turner, Silke R, Brix, Hans-Joachim, Paust, Rolf A K, Stahl, Ulf, Panzer
Publikováno v:
Journal of the American Society of Nephrology : JASN. 29(4)
The IL-17 cytokine family and the cognate receptors thereof have a unique role in organ-specific autoimmunity. Most studies have focused on the founding member of the IL-17 family, IL-17A, as the central mediator of diseases. Indeed, although pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dafda75de411ec763ef104368449ea2
https://pubmed.ncbi.nlm.nih.gov/29551831
https://pubmed.ncbi.nlm.nih.gov/29551831