Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Anna K. Renfrew"'
Autor:
Anna K. Renfrew
Publikováno v:
CHIMIA, Vol 71, Iss 3 (2017)
Metal-based drugs with novel targets and modes of action are increasingly being developed as alternatives to classical platinum(ii) chemotherapeutics. Imaging methods in tumour cells and tissues offer valuable insights into the behaviour of these nov
Externí odkaz:
https://doaj.org/article/9706f2f8ee89421cb107531f666a1591
Autor:
Anna K. Renfrew, David J. Paterson, Catherine K. J. Chen, Trevor W. Hambley, Michela I. Simone, Alexandra Glenister
Publikováno v:
Journal of Medicinal Chemistry. 64:2678-2690
A glucose-based vector for targeting cancer cells conjugated to a tris(methylpyridyl)amine (tpa) ligand to generate targeted chaperone and caging complexes for active anticancer agents is described. The ligand, tpa(CONHPEGglucose)1, inhibits hexokina
Autor:
Murray V. Baker, Massimiliano Massi, Gilles Dujardin, Johannes Zuegg, Peter J. Sadler, Heba A. Mohamed, Alysha G. Elliott, A. Paden King, Angelo Frei, Peter J. Rutledge, Mark A. T. Blaskovich, Christopher L. Brown, Matthew H. Todd, Charlotte E. Willans, Nicole Jung, Anna K. Renfrew, Feng Chen, Stefan Braese, Ahmed M. Mansour, Mark E. Cooper, Justin J. Wilson, John Moat, Christopher G. Dowson
Publikováno v:
Chemical Science. 11:2627-2639
There is a dire need for new antimicrobial compounds to combat the growing threat of widespread antibiotic resistance. With a currently very scarce drug pipeline, consisting mostly of derivatives of known antibiotics, new classes of antibiotics are u
Autor:
Paul J. Dyson, Johannes Karges, Patrycja Nowak-Sliwinska, Gilles Gasser, Rosario Scopelliti, Felix D. Bobbink, Anna K. Renfrew
Publikováno v:
ChemBioChem
ChemBioChem, Wiley-VCH Verlag, In press, ⟨10.1002/cbic.201900236⟩
ChemBioChem, Wiley-VCH Verlag, In press, ⟨10.1002/cbic.201900236⟩
International audience; Cancer is currently one of the deadliest diseases worldwide. Based on the high incidence of this disease, the side-effects associated with current chemotherapies and the appearance of drug resistance, considerable efforts have
Autor:
Feng Chen, Anna K. Renfrew, Alysha G. Elliott, Nicole Jung, Peter J. Rutledge, Murray V. Baker, Peter J. Sadler, Stefan Braese, Johannes Zuegg, Justin J. Wilson, Ahmed M. Mansour, Massimiliano Massi, Angelo Frei, A. Paden King, Gilles Dujardin, Mark E. Cooper, Charlotte E. Willans, John Moat, Christopher G. Dowson, Mark A. T. Blaskovich, Matthew H. Todd, Heba A. Mohamed, Christopher L. Brown
Publikováno v:
Chemical Science
Chemical science, 11 (17), 4531
Chemical science, 11 (17), 4531
There is a dire need for new antimicrobial compounds to combat the growing threat of widespread antibiotic resistance. With a currently very scarce drug pipeline, consisting mostly of derivatives of known antibiotics, new classes of antibiotics are u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e548a04706669f1f0c12f0525b8aa46a
https://eprints.whiterose.ac.uk/161483/1/d0sc90075c.pdf
https://eprints.whiterose.ac.uk/161483/1/d0sc90075c.pdf
Publikováno v:
Metallomics
cis- and trans-Platinum(iv) complexes with diaminetetracarboxylate coordination spheres possess the highly desirable property of exhibiting unusual resistance to reduction by blood serum components and endogenous reductants such as ascorbate. At the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a3821daaa29e4b454a234c0db43c68
https://hdl.handle.net/2123/27300
https://hdl.handle.net/2123/27300
Autor:
Anna K. Renfrew, Stuart M. Grieve, Paul D. Bonnitcha, Elizabeth J. New, G. H. Yin, Edward O'Neill, Jacek L. Kolanowski, Kathryn M. Broadhouse
Publikováno v:
RSC Advances. 6:30021-30027
Cobalt complexes have been extensively used for their catalytic and solid-state magnetic properties, but the solution-state magnetic properties have not yet been widely exploited. Two versatile cobalt ligand scaffolds were investigated for their magn
Autor:
Anna K. Renfrew
Publikováno v:
Encyclopedia of Inorganic and Bioinorganic Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b60ffefb277fc568d0439c0e3b3e96
https://doi.org/10.1002/9781119951438.eibc2634
https://doi.org/10.1002/9781119951438.eibc2634
Autor:
Georg Süss-Fink, Farooq-Ahmad Khan, Lucienne Juillerat-Jeanneret, Anna K. Renfrew, Paul J. Dyson
Arene ruthenium complexes containing long-chain N-ligands L1 = NC5H4–4-COO–C6H4–4-O–(CH2)9–CH3 or L2 = NC5H4–4-COO–(CH2)10–O–C6H4–4-COO–C6H4–4-C6H4–4-CN derived from isonicotinic acid, of the type [(arene)Ru(L)Cl2] (arene =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b63234841b33f302bd4b0e44f9b9587
http://doc.rero.ch/record/320318/files/10876_2010_Article_298.pdf
http://doc.rero.ch/record/320318/files/10876_2010_Article_298.pdf
A series of water-soluble photolabile model complexes of the general formula [Ru([9]aneS3)(chel)(py)]Cl2 ([9]aneS3 = 1,4,7-trithiacyclononane, chel = chelating diimine) was prepared and fully characterized. The photo-triggered release of pyridine wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0738bb8c46929aecc75d41ac154a481
http://hdl.handle.net/11368/2922877
http://hdl.handle.net/11368/2922877