Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Anna K. L. Reyners"'
1
Akademický článek
Levels of circulating tumor DNA correlate with tumor volume in gastro‐intestinal stromal tumors: an exploratory long‐term follow‐up study
Autor: Roos F. Bleckman, Charlotte M. S. C. Haag, Naomi Rifaela, Gerrieke Beukema, Ron H. J. Mathijssen, Neeltje Steeghs, Hans Gelderblom, Ingrid M. E. Desar, Arjen Cleven, Arja terElst, Ed Schuuring, Anna K. L. Reyners
Publikováno v: Molecular Oncology, Vol 18, Iss 11, Pp 2658-2667 (2024)
Patients with gastro‐intestinal stromal tumors (GISTs) undergoing tyrosine kinase inhibitor therapy are monitored with regular computed tomography (CT) scans, exposing patients to cumulative radiation. This exploratory study aimed to evaluate circu
Externí odkaz: https://doaj.org/article/24846d9179084dad86b3bdbabda1dee8
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2
Akademický článek
Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study
Autor: Anneke L. Eerkens, Koen Brummel, Annegé Vledder, Sterre T. Paijens, Marta Requesens, Dominik Loiero, Nienke van Rooij, Annechien Plat, Floris-Jan Haan, Patty Klok, Refika Yigit, Thijs Roelofsen, Natascha M. de Lange, Rie Klomp, David Church, Arja ter Elst, René Wardenaar, Diana Spierings, Floris Foijer, Viktor Hendrik Koelzer, Tjalling Bosse, Joost Bart, Mathilde Jalving, Anna K. L. Reyners, Marco de Bruyn, Hans W. Nijman
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Neoadjuvant immune checkpoint blockade (ICB) has shown unprecedented activity in mismatch repair deficient (MMRd) colorectal cancers, but its effectiveness in MMRd endometrial cancer (EC) remains unknown. In this investigator-driven, phase I
Externí odkaz: https://doaj.org/article/1b7aedf643dd44ed914769ada0de8d61
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3
Akademický článek
The feasibility of a Bayesian network model to assess the probability of simultaneous symptoms in patients with advanced cancer
Autor: Lotte van der Stap, Myrthe F. van Haaften, Esther F. van Marrewijk, Albert H. de Heij, Paula L. Jansen, Janine M. N. Burgers, Melle S. Sieswerda, Renske K. Los, Anna K. L. Reyners, Yvette M. van der Linden
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Although patients with advanced cancer often experience multiple symptoms simultaneously, clinicians usually focus on symptoms that are volunteered by patients during regular history-taking. We aimed to evaluate the feasibility of a Bayesian
Externí odkaz: https://doaj.org/article/79358eb5287643b39d94addf1fd1999b
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4
Akademický článek
A multicenter, dose-finding, phase 1b study of imatinib in combination with alpelisib as third-line treatment in patients with advanced gastrointestinal stromal tumor
Autor: Maria A. Pantaleo, Michael C. Heinrich, Antoine Italiano, Claudia Valverde, Patrick Schöffski, Giovanni Grignani, Anna K. L. Reyners, Sebastian Bauer, Peter Reichardt, Daniel Stark, Ghimja Berhanu, Ulrike Brandt, Tommaso Stefanelli, Hans Gelderblom
Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background Acquired resistance to approved tyrosine kinase inhibitors limits their clinical use in patients with gastrointestinal stromal tumor (GIST). This study investigated the safety, tolerability and efficacy of alpelisib, a phosphatidy
Externí odkaz: https://doaj.org/article/2f1e77cece464909a2d9a3ecf8c75f78
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5
Akademický článek
Evaluating quality of care at the end of life and setting best practice performance standards: a population-based observational study using linked routinely collected administrative databases
Autor: Mariska G. Oosterveld-Vlug, Marianne J. Heins, Manon S. A. Boddaert, Yvonne Engels, Agnes van der Heide, Bregje D. Onwuteaka-Philipsen, Anna K. L. Reyners, Anneke L. Francke
Publikováno v: BMC Palliative Care, Vol 21, Iss 1, Pp 1-9 (2022)
Abstract Background A high percentage of people dying at home, and a low percentage of people being admitted to hospital and dying there are regarded as indicators of appropriate care at the end of life. However, performance standards for these quali
Externí odkaz: https://doaj.org/article/b578a7553bd449d3b9ed4104ff5830ea
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6
Akademický článek
Anti-tumor treatment and healthcare consumption near death in the era of novel treatment options for patients with melanoma brain metastases
Autor: Annemarie C. Eggen, Geke A. P. Hospers, Ingeborg Bosma, Miranda C. A. Kramer, Anna K. L. Reyners, Mathilde Jalving
Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Effective systemic treatments have revolutionized the management of patients with metastatic melanoma, including those with brain metastases. The extent to which these treatments influence disease trajectories close to death is un
Externí odkaz: https://doaj.org/article/dee5d59156ab45beaf89d5e414d20068
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7
Akademický článek
Feasibility of hospital-initiated non-facilitator assisted advance care planning documentation for patients with palliative care needs
Autor: Maaike Kok, Gertruud F. M. van der Werff, Jenske I. Geerling, Jaap Ruivenkamp, Wies Groothoff, Annette W. G. van der Velden, Monique Thoma, Jaap Talsma, Louk G. P. Costongs, Reinold O. B. Gans, Pauline de Graeff, Anna K. L. Reyners
Publikováno v: BMC Palliative Care, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background Advance Care Planning (ACP) and its documentation, accessible to healthcare professionals regardless of where patients are staying, can improve palliative care. ACP is usually performed by trained facilitators. However, ACP conver
Externí odkaz: https://doaj.org/article/7f91f78c5c5c4debbca3e670238bb269
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8
Akademický článek
Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients
Autor: Michiel C. Verboom, Hans Gelderblom, J. Martijn Kerst, Neeltje Steeghs, Anna K. L. Reyners, Stefan Sleijfer, Winette T. A. van der Graaf, Wilbert B. van den Hout
Publikováno v: Sarcoma, Vol 2019 (2019)
Trabectedin and ifosfamide are among the few cytostatic agents active in advanced soft tissue sarcomas (STSs). Trabectedin is most potent against so-called L-sarcomas (leiomyosarcoma and liposarcoma). The survival gain and cost-effectiveness of these
Externí odkaz: https://doaj.org/article/e89292ff05dc4d31a6b0b64e07dc7821
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10
Symptoms reported by gastrointestinal stromal tumour (GIST) patients on imatinib treatment: combining questionnaire and forum data
Autor: Dide den Hollander, Anne R. Dirkson, Suzan Verberne, Wessel Kraaij, Gerard van Oortmerssen, Hans Gelderblom, Astrid Oosten, Anna K. L. Reyners, Neeltje Steeghs, Winette T. A. van der Graaf, Ingrid M. E. Desar, Olga Husson
Publikováno v: Supportive Care in Cancer, 30, 5137-5146
Supportive Care in Cancer
Supportive Care in Cancer, 30(6), 5137-5146. SPRINGER
Supportive Care in Cancer, 30(6), 5137-5146. Springer-Verlag
Supportive Care in Cancer. SPRINGER
Supportive Care in Cancer, 30, 6, pp. 5137-5146
Purpose Treatment with the tyrosine kinase inhibitor (TKI) imatinib in patients with gastrointestinal stromal tumours (GIST) causes symptoms that could negatively impact health-related quality of life (HRQoL). Treatment-related symptoms are usually c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9608fd4f9adf043ed7e59538c1a979
https://doi.org/10.1007/s00520-022-06929-3
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