Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anna Jirovec"'
Autor:
Anna Jirovec, Ashley Flaman, Elena Godbout, Daniel Serrano, Joel Werier, Bibianna Purgina, Jean-Simon Diallo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Dedifferentiated liposarcoma (DDLS) is an aggressive, recurring sarcoma with limited treatments. T-cell immunotherapies selectively target malignant cells, holding promise against DDLS. The development of successful immunotherapy for DDLS re
Externí odkaz:
https://doaj.org/article/42e4a4db2bd24d3f9f68e73d9674012a
Autor:
Nouf Alluqmani, Anna Jirovec, Zaid Taha, Oliver Varette, Andrew Chen, Daniel Serrano, Glib Maznyi, Sarwat Khan, Nicole E. Forbes, Rozanne Arulanandam, Rebecca C. Auer, Jean-Simon Diallo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Oncolytic viruses (OVs) are promising anticancer treatments that specifically replicate in and kill cancer cells and have profound immunostimulatory effects. We previously reported the potential of vanadium-based compounds such as vanadyl sulfate (VS
Externí odkaz:
https://doaj.org/article/31b68295a0e340bdba30274553e1eac0
Autor:
Mathieu J. F. Crupi, Zaid Taha, Thijs J. A. Janssen, Julia Petryk, Stephen Boulton, Nouf Alluqmani, Anna Jirovec, Omar Kassas, Sarwat T. Khan, Sydney Vallati, Emily Lee, Ben Zhen Huang, Michael Huh, Larissa Pikor, Xiaohong He, Ricardo Marius, Bradley Austin, Jessie Duong, Adrian Pelin, Serge Neault, Taha Azad, Caroline J. Breitbach, David F. Stojdl, Michael F. Burgess, Scott McComb, Rebecca Auer, Jean-Simon Diallo, Carolina S. Ilkow, John Cameron Bell
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Colorectal cancer is the third most diagnosed cancer and the second leading cause of cancer mortality worldwide, highlighting an urgent need for new therapeutic options and combination strategies for patients. The orchestration of potent T cell respo
Externí odkaz:
https://doaj.org/article/29d21675c815413ebbf0f96fc31a0567
Oncolytic Rhabdovirus Vaccine Boosts Chimeric Anti-DEC205 Priming for Effective Cancer Immunotherapy
Autor:
Fanny Tzelepis, Harsimrat Kaur Birdi, Anna Jirovec, Silvia Boscardin, Christiano Tanese de Souza, Mohsen Hooshyar, Andrew Chen, Keara Sutherland, Robin J. Parks, Joel Werier, Jean-Simon Diallo
Publikováno v:
Molecular Therapy: Oncolytics, Vol 19, Iss , Pp 240-252 (2020)
Prime-boost vaccination employing heterologous viral vectors encoding an antigen is an effective strategy to maximize the antigen-specific immune response. Replication-deficient adenovirus serotype 5 (Ad5) is currently being evaluated clinically in N
Externí odkaz:
https://doaj.org/article/85c0f1ffc30c4c7e93249fbf227e89f3
Autor:
Carolyn Nessim, Jean-Simon Diallo, Harsimrat Kaur Birdi, Anna Jirovec, Serena Cortés-Kaplan, Joel Werier, Michele Ardolino
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Sarcomas are a rare malignancy of mesenchymal tissues, comprizing a plethora of unique subtypes, with more than 60 types. The sheer heterogeneity of disease phenotype makes this a particularly difficult cancer to treat. Radiotherapy, chemotherapy and
Externí odkaz:
https://doaj.org/article/e1fe72d8937549b89ab948186d980f96
Autor:
Matthew J. Atherton, Kyle B. Stephenson, Fanny Tzelepis, David Bakhshinyan, Jake K. Nikota, Hwan Hee Son, Anna Jirovec, Charles Lefebvre, Anna Dvorkin-Gheva, Ali A. Ashkar, Yonghong Wan, David F. Stojdl, Eric C. Belanger, Rodney H. Breau, John C. Bell, Fred Saad, Sheila K. Singh, Jean-Simone Diallo, Brian D. Lichty
Publikováno v:
OncoImmunology, Vol 7, Iss 7 (2018)
Prostate cancer (PCa) was estimated to have the second highest global incidence rate for male non-skin tumors and is the fifth most deadly in men thus mandating the need for novel treatment options. MG1-Maraba is a potent and versatile oncolytic viru
Externí odkaz:
https://doaj.org/article/44bc5ab425ff4979b88e6403354f4852
Autor:
Zaid Taha, Rozanne Arulanandam, Glib Maznyi, Elena Godbout, Madalina E. Carter-Timofte, Naziia Kurmasheva, Line S. Reinert, Andrew Chen, Mathieu J.F. Crupi, Stephen Boulton, Geneviève Laroche, Alexandra Phan, Reza Rezaei, Nouf Alluqmani, Anna Jirovec, Alexandra Acal, Emily E.F. Fekete, Ragunath Singaravelu, Julia Petryk, Manja Idorn, Kyle G. Potts, Hayley Todesco, Cini John, Douglas J. Mahoney, Carolina S. Ilkow, Patrick Giguère, Tommy Alain, Marceline Côté, Søren R. Paludan, David Olagnier, John C. Bell, Taha Azad, Jean-Simon Diallo
Publikováno v:
Taha, Z, Arulanandam, R, Maznyi, G, Godbout, E, Carter-Timofte, M E, Kurmasheva, N, Reinert, L S, Chen, A, Crupi, M J F, Boulton, S, Laroche, G, Phan, A, Rezaei, R, Alluqmani, N, Jirovec, A, Acal, A, Brown, E E F, Singaravelu, R, Petryk, J, Idorn, M, Potts, K G, Todesco, H, John, C, Mahoney, D J, Ilkow, C S, Giguère, P, Alain, T, Côté, M, Paludan, S R, Olagnier, D, Bell, J C, Azad, T & Diallo, J-S 2022, ' Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen ', Molecular Therapy, vol. 30, no. 9, pp. 2998-3016 . https://doi.org/10.1016/j.ymthe.2022.04.025
We established a split nanoluciferase complementation assay to rapidly screen for inhibitors that interfere with binding of the receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein with
Autor:
Anabel Bergeron, Vanessa Garcia, Rozanne Arulanandam, Fanny Tzelepis, Jean-Simon Diallo, Harsimrat Kaur Birdi, Anne Landry, Andrew Chen, Anna Jirovec, Oliver Varette, Keara Sutherland, Mohammed Selman, Zaid Taha, Nouf Alluqmani, Elizabeth Macdonald, Barbara C. Vanderhyden
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-10 (2020)
Communications Biology
Communications Biology
We have demonstrated that microtubule destabilizing agents (MDAs) can sensitize tumors to oncolytic vesicular stomatitis virus (VSVΔ51) in various preclinical models of cancer. The clinically approved T-DM1 (Kadcyla®) is an antibody-drug conjugate
Oncolytic rhabdovirus vaccine boosts chimeric Anti-DEC205 priming for effective cancer immunotherapy
Autor:
Robin J. Parks, Mohsen Hooshyar, Silvia Beatriz Boscardin, Fanny Tzelepis, Keara Sutherland, Harsimrat Kaur Birdi, Joel Werier, Jean-Simon Diallo, Andrew Chen, Anna Jirovec, Christiano Tanese de Souza
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Molecular Therapy: Oncolytics, Vol 19, Iss, Pp 240-252 (2020)
Molecular Therapy Oncolytics
Universidade de São Paulo (USP)
instacron:USP
Molecular Therapy: Oncolytics, Vol 19, Iss, Pp 240-252 (2020)
Molecular Therapy Oncolytics
Prime-boost vaccination employing heterologous viral vectors encoding an antigen is an effective strategy to maximize the antigen-specific immune response. Replication-deficient adenovirus serotype 5 (Ad5) is currently being evaluated clinically in N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d0fd8e44f5714ec9ec9da4d8144005
Autor:
Harsimrat Kaur Birdi, Carolyn Nessim, Jean-Simon Diallo, Joel Werier, Serena Cortés-Kaplan, Anna Jirovec, Michele Ardolino
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Sarcomas are a rare malignancy of mesenchymal tissues, comprizing a plethora of unique subtypes, with more than 60 types. The sheer heterogeneity of disease phenotype makes this a particularly difficult cancer to treat. Radiotherapy, chemotherapy and