Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anna Janostakova"'
Autor:
Yong Zhao, Zhaoshun Jiang, Elias Delgado, Heng Li, Huimin Zhou, Wei Hu, Marcos Perez‐Basterrechea, Anna Janostakova, Qidong Tan, Jing Wang, Mao Mao, Zhaohui Yin, Ye Zhang, Ying Li, Quanhai Li, Jing Zhou, Yunxiang Li, Eva Martinez Revuelta, Jose Maria García‐Gala, Honglan Wang, Silvia Perez‐Lopez, Maria Alvarez‐Viejo, Edelmiro Menendez, Thomas Moss, Edward Guindi, Jesus Otero
Publikováno v:
Stem Cells Translational Medicine, Vol 6, Iss 8, Pp 1684-1697 (2017)
Abstract Diabetes is a major global health issue and the number of individuals with type 1 diabetes (T1D) and type 2 diabetes (T2D) increases annually across multiple populations. Research to develop a cure must overcome multiple immune dysfunctions
Externí odkaz:
https://doaj.org/article/d41c029b664845b594bb95847e335e45
Autor:
Mao Mao, Yong Zhao, Marcos Perez-Basterrechea, Honglan Wang, Jose Maria Garcia-Gala, María Álvarez-Viejo, Ying Li, Qidong Tan, Edelmiro Menéndez, Wei Hu, Zhaohui Yin, Ye Zhang, Heng Li, Huimin Zhou, Jing Wang, Quanhai Li, Anna Janostakova, Edward Guindi, Elías Delgado, Jing Zhou, Yunxiang Li, J. Otero, Eva Martinez Revuelta, Zhaoshun Jiang, Thomas Moss, Silvia Perez-Lopez
Publikováno v:
Stem Cells Translational Medicine, Vol 6, Iss 8, Pp 1684-1697 (2017)
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Stem Cells Translational Medicine
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Stem Cells Translational Medicine
Clinical trials in Chinese T1D and T2D subjects were supportedby the China Jinan 5150 Program. Spanish clinical trial was sup-ported by the grants from the European Union FEDER funds,Principado de Asturias and FICYT (GRUPIN 14–069)
Zhao, Y., J
Zhao, Y., J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a471a2a61ff8bf04558c233ee4e179c2
https://doi.org/10.1002/sctm.17-0078
https://doi.org/10.1002/sctm.17-0078
Autor:
Shudong Wang, Jiri Klinot, Vera Noskova, Simon Parsons, V. Krecek, Jan Sarek, Nikolai Zhelev, Eva Klinotová, Peter Fischer, Jean Oliver Thomson, Gabriela Korinkova, Petr Dzubak, Marian Hajduch, Anna Janostakova
Publikováno v:
Journal of Medicinal Chemistry. 46:5402-5415
Cellular screening of various synthetic triterpenoid compounds formally derived from lupane has identified a number of analogues as potential anticancer drug candidates. Here we describe the synthesis and structure-activity relationships of betulin a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76f7af4d6f92bf0ae20c50285bffdd6
https://doi.org/10.1021/jm020854p
https://doi.org/10.1021/jm020854p
Autor:
Magdalena Cizkova, Katerina Bouchalova, David Friedecky, Adriana Polynkova, Anna Janostakova, Lenka Radova, Karel Cwiertka, Radek Trojanec, Michaela Zezulova, Miloslava Zlevorova, Marian Hajduch, Bohuslav Melichar
Publikováno v:
Tumori. 98(1)
Aims and Background Lapatinib is a tyrosine kinase inhibitor targeting epidermal growth factor receptors 1 (EGFR/HER1) and 2 (HER2) used in the treatment of patients with HER2-positive breast cancer. The aim of the present study was to determine lapa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6022883f9cfba954bddcb00b1da48b22
https://pubmed.ncbi.nlm.nih.gov/22495718
https://pubmed.ncbi.nlm.nih.gov/22495718
Publikováno v:
Clinical drug investigation. 26(6)
Background and objective: Endothelin-1 (ET-1) is produced by vascular endothelial cells and epithelial cells, T-lymphocytes and phagocytes. Increased ET-1 levels have been demonstrated in the bronchial epithelium of asthma patients. In vitro, ET-1 st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa4b6c2479ab5810856a0c1e171fa1b
https://pubmed.ncbi.nlm.nih.gov/17163269
https://pubmed.ncbi.nlm.nih.gov/17163269
Autor:
Vladimir, Mihal, Marian, Hajduch, Vera, Noskova, Anna, Janostakova, Maria, Safarova, Miroslav, Orel, Galina, Kouzmina, Jan, Stary, Bohuslav, Blazek, Dagmar, Pospisilova
Publikováno v:
Bulletin du cancer. 91(4)
This study was designed to assess the predictive value of an MTT (3-[4,5-dimethylthiazol-2,5-diphenyl] tetrazolium bromide) in vitro assay for the evaluation of leukemic cell resistance/sensitivity to cytotoxic drugs, and to compare these results wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24f23b5422f88f12e8db29b27906e6a3
https://pubmed.ncbi.nlm.nih.gov/15562558
https://pubmed.ncbi.nlm.nih.gov/15562558
Autor:
Miroslav Soural, Dalibor Dolezal, Petr Dzubak, Jan Hlaváč, Ivo Frydrych, Dusan Holub, Petr Konecny, Gabriela Rylova, Marian Hajduch, Tomas Ozdian, Anna Janostakova
Publikováno v:
Cancer Research. 74:4624-4624
Quinolinones, compounds derived from quinolone antibiotics, are well known for their antibacterial, antiprotozoal, cytotoxic and immunosuppressive effects. Screening of collection of small molecules revealed 2-phenyl-3-hydroxy-4(1H)-quinolinones as m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316b5131df4a6386db93f51d57a69aaa
https://doi.org/10.1158/1538-7445.am2014-4624
https://doi.org/10.1158/1538-7445.am2014-4624
Autor:
Marian Hajduch, Petr Dzubak, Dalibor Dolezal, Ivo Frydrych, Dusan Holub, Petr Konecny, Jan Hlaváč, Gabriela Rylova, Miroslav Soural, Anna Janostakova, Tomas Ozdian
Publikováno v:
Cancer Research. 72:4748-4748
Currently, we are testing chemical libraries of quinolinone derivatives, compounds with high selective cytotoxic activity. These compounds, derived from quinolone antibiotics, are well known for their antibacterial, antiprotozoal, cytotoxic and immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d9e5e0fad002a1a726575ff8c27ea11
https://doi.org/10.1158/1538-7445.am2012-4748
https://doi.org/10.1158/1538-7445.am2012-4748
Autor:
Marian Hajduch, Jiri Rehulka, Petr Dzubak, Tomas Ozdian, Martin Vlk, Dusan Holub, Jan Sarek, Anna Janostakova
Publikováno v:
Cancer Research. 71:2641-2641
Betulinic acid and its derivatives are cytotoxic compounds with the specific effect to the tumor cells. In our betulinic acid derivative chemical library we have identified several potent compounds which were highly active in the wide spectrum of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db6dbd0826a1708c8b71c19cec7e393f
https://doi.org/10.1158/1538-7445.am2011-2641
https://doi.org/10.1158/1538-7445.am2011-2641
Autor:
Adriana Polynkova, Marian Hajduch, Anna Janostakova, Zdenek Kolar, David Friedecky, Marta Dziechciarkova, Katerina Bouchalova, Lenka Radová, Bohuslav Melichar, Karel Cwiertka, Magdalena Cizkova, Radek Trojanec
Publikováno v:
Cancer Genetics and Cytogenetics. 203:77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7804d6f68e65e528d9d7d7ec6304d5ef
https://doi.org/10.1016/j.cancergencyto.2010.07.072
https://doi.org/10.1016/j.cancergencyto.2010.07.072