Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna J. Hagen"'
Autor:
John P. Hennessey, Dephillips Peter A, Anna J. Hagen, C. Oliver, B. Buckland, Robert D. Sitrin, M. Armstrong, John G. Aunins, C. B. Oswald, Orella Charles J, John A. Lewis
Publikováno v:
Scopus-Elsevier
Manufacture of VAQTA®, an inactivated hepatitis A vaccine, uses state-of-the-art technologies in cell culture and bioprocessing science, which have made it possible to routinely produce the vaccine at manufacturing scale. VAQTA® consists of an atte
Publikováno v:
Biotechnology Techniques. 12:439-443
An 8 minute HPLC immunoaffinity assay for hepatitis A intact virus (HAV) was developed using an activated aldehyde perfusive support and a purified monoclonal antibody. The assay is linear, reproducible, and sensitive for the evaluation of HAV in cru
Publikováno v:
Biotechnology and Bioengineering. 56:83-88
Solvent extraction is a very powerful purification step in the preparation of VAQTA, a highly purified, inactivated hepatitis A vaccine. Extraction of an aqueous product-containing protein solution with chloroform through vigorous shaking causes irre
Publikováno v:
Biotechnology Progress. 12:406-412
Poly(ethylene glycol) precipitation has been successfully used to concentrate and purify hepatitis A virus from crude lysate preparations for production of VAQTA, a highly purified, formalin-inactivated hepatitis A vaccine. Initial results showed tha
Publikováno v:
Biotechnology and Bioengineering. 35:955-965
A novel process has been developed which uses reversed micelles to isolate denatured protein molecules from each other and allows them to refold individually. These reversed micelles are aqueous phase droplets stabilized by the surfactant AOT and sus
Publikováno v:
Pure and Applied Chemistry. 54:2181-2188
This is the publisher's version, also available electronically from "http://www.degruyter.com".
Publikováno v:
Polymer Bulletin. 5
Sulfinate functional groups have been introduced on selected positions of the aromatic rings of soluble or crosslinked polystyrene via lithiation reactions followed by quenching with sulfur dioxide. The sulfinate polymers have good stability, can be