Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna J Kochanowska-Karamyan"'
Autor:
Abir T. El-Alfy, Mitchell A. Avery, Xiong Zhang, Jakob Magolan, Anna J Kochanowska-Karamyan, Hugo C. Araujo, Mark T. Hamann, Paulo Carvalho, Stephen D Holmbo
Publikováno v:
Journal of Natural Products. 83:1092-1098
The natural product veranamine was isolated from the marine sponge Verongula rigida. It contains a unique heterocyclic scaffold and demonstrates in vivo antidepressant activity and selective affinity for 5HT2B and sigma-1 receptors. The first total s
Autor:
Mohamed A. Ibrahim, Abir T. El-Alfy, Kelly Ezel, Mohamed O. Radwan, Abbas G. Shilabin, Anna J. Kochanowska-Karamyan, Howaida I. Abd-Alla, Masami Otsuka, Mark T. Hamann
Publikováno v:
Marine Drugs, Vol 15, Iss 8, p 248 (2017)
In previous studies, we have isolated several marine indole alkaloids and evaluated them in the forced swim test (FST) and locomotor activity test, revealing their potential as antidepressant and sedative drug leads. Amongst the reported metabolites
Externí odkaz:
https://doaj.org/article/694d2c96306045258ac577da22f0026e
Autor:
Anna J, Kochanowska-Karamyan, Hugo C, Araujo, Xiong, Zhang, Abir, El-Alfy, Paulo, Carvalho, Mitchell A, Avery, Stephen D, Holmbo, Jakob, Magolan, Mark T, Hamann
Publikováno v:
Journal of natural products. 83(4)
The natural product veranamine was isolated from the marine sponge
Autor:
Judith V. Hobrath, Mark T. Hamann, Ngolui Rene Fuanta, Angela I. Calderón, Anna J Kochanowska-Karamyan, Johayra Simithy, Douglas C. Goodwin
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1866:731-739
Ilimaquinone (IQ), a marine sponge metabolite, has been considered as a potential therapeutic agent for various diseases due to its broad range of biological activities. We show that IQ irreversibly inactivates Mycobacterium tuberculosis shikimate ki
Autor:
Anna J, Kochanowska-Karamyan
Publikováno v:
International journal of pharmaceutical compounding. 20(5)
Historically, compounding has been always an integral part of pharmacy. Medications were prepared by pharmacists for individual patients and compounding was the only source of drugs before mass production by pharmaceutical companies. This trend start
Autor:
Mark T. Hamann, Anna J Kochanowska-Karamyan, Joonseok Oh, Robert J. Doerksen, In Hyun Hwang, MinKyun Na
A novel phenyl alkene ( 1 ) was isolated from a mixture of three Florida sponges, Smenospongia aurea , Smenospongia cerebriformis , and Verongula rigida . Unlike terpenoids or amino acid derivatives, which are commonly known classes of secondary meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05dd06913c3194dc15e5826f8955b237
https://europepmc.org/articles/PMC5085269/
https://europepmc.org/articles/PMC5085269/
The marine environment has been explored in the search for new bioactive compounds over the last 50 years, becoming a highly important and rich source of potent molecules and drug leads reported to possess a wide scope of activities. Alkaloids consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de6d0b8999886b63eca92f9b17a1df6
https://europepmc.org/articles/PMC2922063/
https://europepmc.org/articles/PMC2922063/