Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Anna Isermann"'
Publikováno v:
Cells, Vol 12, Iss 20, p 2427 (2023)
Background: Heavy ion irradiation (IR) with high-linear energy transfer (LET) is characterized by a unique depth dose distribution and increased biological effectiveness. Following high-LET IR, localized energy deposition along the particle trajector
Externí odkaz:
https://doaj.org/article/7028ccd34ec14529ac8410ef8b0e6441
Autor:
Claudia E. Rübe, Caroline Bäumert, Nadine Schuler, Anna Isermann, Zoé Schmal, Matthias Glanemann, Carl Mann, Harry Scherthan
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during
Externí odkaz:
https://doaj.org/article/d87dc7743f364e58867d576df1284703
Autor:
Mutaz A. Abd Al-razaq, Benjamin M. Freyter, Anna Isermann, Gargi Tewary, Adèle Mangelinck, Carl Mann, Claudia E. Rübe
Publikováno v:
Cells, Vol 12, Iss 6, p 916 (2023)
Purpose: Radiation-induced senescence is characterized by profound changes in chromatin organization with the formation of Senescence-Associated-Heterochromatin-Foci (SAHF) and DNA-Segments-with-Chromatin-Alterations-Reinforcing-Senescence (DNA-SCARS
Externí odkaz:
https://doaj.org/article/e7809fbcf44042659e69ff74b32839f6
Autor:
Benjamin M. Freyter, Mutaz A. Abd Al-razaq, Anna Isermann, Anne Dietz, Omid Azimzadeh, Liesbeth Hekking, Maria Gomolka, Claudia E. Rübe
Publikováno v:
Cells, Vol 11, Iss 2, p 273 (2022)
Irreparable DNA damage following ionizing radiation (IR) triggers prolonged DNA damage response and induces premature senescence. Cellular senescence is a permanent state of cell-cycle arrest characterized by chromatin restructuring, altered nuclear
Externí odkaz:
https://doaj.org/article/41f263b482ca42768829afc09bdba22d
Autor:
Zoé Schmal, Caroline Bäumert, Harry Scherthan, Nadine Schuler, Claudia E. Rübe, Carl Mann, Anna Isermann, Matthias Glanemann
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-11 (2021)
NPJ Aging and Mechanisms of Disease
NPJ Aging and Mechanisms of Disease
Cellular senescence is an irreversible growth arrest that occurs as a result of damaging stimuli, including DNA damage and/or telomere shortening. Here, we investigate histone variant H2A.J as a new biomarker to detect senescent cells during human sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c27366a383f59bb493012450a4b5d9
https://doaj.org/article/d87dc7743f364e58867d576df1284703
https://doaj.org/article/d87dc7743f364e58867d576df1284703
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9130, p 9130 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), ⟨10.3390/ijms21239130⟩
Volume 21
Issue 23
International Journal of Molecular Sciences, 2020, 21 (23), ⟨10.3390/ijms21239130⟩
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (23), ⟨10.3390/ijms21239130⟩
Volume 21
Issue 23
International Journal of Molecular Sciences, 2020, 21 (23), ⟨10.3390/ijms21239130⟩
Irreparable double-strand breaks (DSBs) in response to ionizing radiation (IR) trigger prolonged DNA damage response (DDR) and induce premature senescence. Profound chromatin reorganization with formation of senescence-associated heterochromatin foci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfdf4833540e01a3dd6e7636f19ddd59
https://www.mdpi.com/1422-0067/21/23/9130
https://www.mdpi.com/1422-0067/21/23/9130
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7638, p 7638 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 14
International Journal of Molecular Sciences
Volume 22
Issue 14
Background: Charged-particle radiotherapy is an emerging treatment modality for radioresistant tumors. The enhanced effectiveness of high-energy particles (such as heavy ions) has been related to the spatial clustering of DNA lesions due to highly lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784fc69cc74bcf99ccc86bb4f1475885
https://doi.org/10.3390/ijms22147638
https://doi.org/10.3390/ijms22147638
Autor:
Soile Tapio, Christine von Toerne, Daniela Hladik, Anna Isermann, Claudia E. Rübe, Zoé Schmal
Publikováno v:
Radiother. Oncol. 137, 45-54 (2019)
Background and purpose: High-precision radiotherapy is an effective treatment modality for tumors. Intensity-modulated radiotherapy techniques permit close shaping of high doses to tumors, however healthy organs outside the target volume are repeated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407603d0d783e2a5308040e9a354ccd4
https://pubmed.ncbi.nlm.nih.gov/31063923
https://pubmed.ncbi.nlm.nih.gov/31063923