Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Anna Hošťálková"'
Autor:
Kateřina Hradiská Breiterová, Aneta Ritomská, Diana Fontinha, Jana Křoustková, Daniela Suchánková, Anna Hošťálková, Marcela Šafratová, Eliška Kohelová, Rozálie Peřinová, Rudolf Vrabec, Denise Francisco, Miguel Prudêncio, Lucie Cahlíková
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 1007 (2023)
The incidence rate of malaria and the ensuing mortality prompts the development of novel antimalarial drugs. In this work, the activity of twenty-eight Amaryllidaceae alkaloids (1–28) belonging to seven different structural types was assessed, as w
Externí odkaz:
https://doaj.org/article/5d092062cf334c5a91abe4f5fd1bdbb9
Autor:
Mst Shamima Parvin, Jakub Chlebek, Anna Hošťálková, Maria Carmen Catapano, Zuzana Lomozová, Kateřina Macáková, Přemysl Mladěnka
Publikováno v:
Molecules, Vol 27, Iss 19, p 6429 (2022)
Data on alkaloid interactions with the physiologically important transition metals, iron and copper, are mostly lacking in the literature. However, these interactions can have important consequences in the treatment of both Alzheimer’s disease and
Externí odkaz:
https://doaj.org/article/26dde2bc38ac4d9db9e8ef5bed451e36
Autor:
Viriyanata Wijaya, Ondřej Janďourek, Jana Křoustková, Kateřina Hradiská-Breiterová, Jan Korábečný, Kateřina Sobolová, Eliška Kohelová, Anna Hošťálková, Klára Konečná, Marcela Šafratová, Rudolf Vrabec, Jiří Kuneš, Lubomír Opletal, Jakub Chlebek, Lucie Cahlíková
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 844 (2022)
Tuberculosis (TB) is a widespread infectious disease caused by Mycobacterium tuberculosis. The increasing incidence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has created a need for new antiTB agents with new chemical s
Externí odkaz:
https://doaj.org/article/7d7edd4993bd478abebcbfeee939312a
Autor:
Negar Maafi, Abdullah Al Mamun, Ondřej Janďourek, Jana Maříková, Kateřina Breiterová, Adéla Diepoltová, Klára Konečná, Anna Hošťálková, Daniela Hulcová, Jiří Kuneš, Eliška Kohelová, Darja Koutová, Marcela Šafratová, Lucie Nováková, Lucie Cahlíková
Publikováno v:
Molecules, Vol 26, Iss 19, p 6023 (2021)
The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more than 1.4 million people worldwide each year. Nine Amaryllidaceae alkaloid
Externí odkaz:
https://doaj.org/article/4050f680840c4d96813412ba50368aac
Autor:
Darja Koutova, Monika Kulhava, Radim Havelek, Martina Majorosova, Karel Královec, Klara Habartova, Anna Hošťálková, Lubomír Opletal, Lucie Cahlikova, Martina Řezáčová
Publikováno v:
Molecules, Vol 25, Iss 4, p 964 (2020)
Bersavine is the new bisbenzylisoquinoline alkaloid isolated from the Berberis vulgaris L. (Berberidaceae) plant. The results of cytotoxicity screening 48 h post-treatment showed that bersavine considerably inhibits the proliferation and viability of
Externí odkaz:
https://doaj.org/article/887e44d3d56a45b19733abc35394203b
Autor:
Kateřina Breiterová, Darja Koutová, Jana Maříková, Radim Havelek, Jiří Kuneš, Martina Majorošová, Lubomír Opletal, Anna Hošťálková, Jaroslav Jenčo, Martina Řezáčová, Lucie Cahlíková
Publikováno v:
Plants, Vol 9, Iss 2, p 137 (2020)
In this detailed phytochemical study of Narcissus cv. Professor Einstein, we isolated 23 previously known Amaryllidaceae alkaloids (1−23) of several structural types and one previously undescribed alkaloid, 7-oxonorpluviine. The chemical structures
Externí odkaz:
https://doaj.org/article/3a90bdd9d77f48cab42e08108628f5de
Autor:
Jakub Chlebek, Jan Korábečný, Rafael Doležal, Šárka Štěpánková, Daniel I. Pérez, Anna Hošťálková, Lubomír Opletal, Lucie Cahlíková, Kateřina Macáková, Tomáš Kučera, Martina Hrabinová, Daniel Jun
Publikováno v:
Molecules, Vol 24, Iss 7, p 1340 (2019)
In recent studies, several alkaloids acting as cholinesterase inhibitors were isolated from Corydalis cava (Papaveraceae). Inhibitory activities of (+)-thalictricavine (1) and (+)-canadine (2) on human acetylcholinesterase (hAChE) and butyrylcholines
Externí odkaz:
https://doaj.org/article/4222d098d41c4d2aa46c3ac96c25eacb
Autor:
Daniela Hulcová, Kateřina Breiterová, Tomáš Siatka, Kamila Klímová, Lara Davani, Marcela Šafratová, Anna Hošťálková, Angela De Simone, Vincenza Andrisano, Lucie Cahlíková
Publikováno v:
Molecules, Vol 23, Iss 4, p 719 (2018)
Glycogen synthase kinase-3β (GSK-3β) is a multifunctional serine/threonine protein kinase that was originally identified as an enzyme involved in the control of glycogen metabolism. It plays a key role in diverse physiological processes including m
Externí odkaz:
https://doaj.org/article/ed115e823d9d431284ea970c505208b3
Autor:
Viriyanata, Wijaya, Ondřej, Janďourek, Jana, Křoustková, Kateřina, Hradiská-Breiterová, Jan, Korábečný, Kateřina, Sobolová, Eliška, Kohelová, Anna, Hošťálková, Klára, Konečná, Marcela, Šafratová, Rudolf, Vrabec, Jiří, Kuneš, Lubomír, Opletal, Jakub, Chlebek, Lucie, Cahlíková
Publikováno v:
Biomolecules. 12(6)
Tuberculosis (TB) is a widespread infectious disease caused by
Autor:
Rudolf, Vrabec, Jana, Maříková, Miroslav, Ločárek, Jan, Korábečný, Daniela, Hulcová, Anna, Hošťálková, Jiří, Kuneš, Jakub, Chlebek, Tomáš, Kučera, Martina, Hrabinová, Daniel, Jun, Ondřej, Soukup, Vincenza, Andrisano, Jaroslav, Jenčo, Marcela, Šafratová, Lucie, Nováková, Lubomír, Opletal, Lucie, Cahlíková
Publikováno v:
Phytochemistry. 194
One undescribed indole alkaloid together with twenty-two known compounds have been isolated from aerial parts of Vinca minor L. (Apocynaceae). The chemical structures of the isolated alkaloids were determined by a combination of MS, HRMS, 1D, and 2D