Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Anna Hester"'
Autor:
Anna Hester, Franziska Henze, Anna Marie Debes, Charlotte Leonie Schubert, Alexander Koenig, Nadia Harbeck, Rachel Wuerstlein
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundSince the European approval of CDK4/6 inhibitors in 2016, the treatment of patients with hormone-receptor-positive, HER2-negative metastatic breast cancer has changed significantly. Compared with chemotherapy, endocrine-based therapy has di
Externí odkaz:
https://doaj.org/article/66d7d0cb722749a39c3051bc33a39db6
Autor:
Susann Badmann, Doris Mayr, Elisa Schmoeckel, Anna Hester, Christina Buschmann, Susanne Beyer, Thomas Kolben, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract In recurrent epithelial ovarian cancer (EOC) most patients develop platinum-resistance. On molecular level the NRF2 pathway, a cellular defense mechanism against reactive oxygen species, is induced. In this study, we investigate AKR1C1/2, ta
Externí odkaz:
https://doaj.org/article/51dfe0d42da94dd1b154d81478a61c37
Autor:
Anna Hester Marotti Magalhaes, Kévila Kelma Nascimento Silva dos Passos, Katiúcia Dias Fernandes, Hisaias de Souza Almeida
Publikováno v:
Agro@mbiente On-line, Vol 16 (2022)
Studies aiming to understand native species seeds permanence in the seed bank of a forest may enhance the knowledge about forest ecology and the ecological restoration of degraded and/or disturbed environments. Therefore, the work aimed to evaluate H
Externí odkaz:
https://doaj.org/article/a8affffc28264520b550332e0b4d51cd
Autor:
Lili Lin, Christina Kuhn, Nina Ditsch, Thomas Kolben, Bastian Czogalla, Susanne Beyer, Fabian Trillsch, Elisa Schmoeckel, Doris Mayr, Sven Mahner, Udo Jeschke, Anna Hester
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-16 (2021)
Abstract Background An abundance of tumor-associated macrophages has been shown to be an independent prognostic factor for a poor prognosis of human breast cancer (BC). Adipose tissue accounts for the largest proportion of the breast and has also bee
Externí odkaz:
https://doaj.org/article/b079fccf2b264727a13d7de0710e4203
Autor:
Yue Liao, Susann Badmann, Fabian Kraus, Nicole Elisabeth Topalov, Doris Mayr, Thomas Kolben, Anna Hester, Susanne Beyer, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla, Alexander Burges
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 882 (2023)
Past studies have confirmed that aberrant activation of the Wnt/β-catenin signaling is associated with tumorigenesis and metastasis in breast cancer, while the role of platelet-activating factor acetylhydrolase (PLA2G7/PAF-AH) in this signaling path
Externí odkaz:
https://doaj.org/article/8090015b4301495586f94e0efd72b3f6
Autor:
Nicole Elisabeth Topalov, Doris Mayr, Clemens Scherer, Anca Chelariu-Raicu, Susanne Beyer, Anna Hester, Fabian Kraus, Mingjun Zheng, Till Kaltofen, Thomas Kolben, Alexander Burges, Sven Mahner, Fabian Trillsch, Udo Jeschke, Bastian Czogalla
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The impact of Actin beta-like 2 (ACTBL2), a novel described actin isoform, on epithelial ovarian cancer (EOC) biology has not been investigated so far. In this study, we analyzed the prognostic and functional significance of ACTBL2 and its regulatory
Externí odkaz:
https://doaj.org/article/a8ab4bea62a044918dd18ca46829d427
Autor:
Bastian Czogalla, Alexandra Partenheimer, Susann Badmann, Elisa Schmoeckel, Doris Mayr, Thomas Kolben, Susanne Beyer, Anna Hester, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100910- (2021)
Background:: Enolase-1, primarily known for its role in glucose metabolism, is overexpressed in various cancer entities. In contrast its alternative spliced nuclear isoform MBP-1 acts as a tumor suppressor. The aim of this study is to analyze the pro
Externí odkaz:
https://doaj.org/article/10b346fbbd114b0487ee2ccde22428e1
Autor:
Sabine Heublein, Udo Jeschke, Cornelia Sattler, Christina Kuhn, Anna Hester, Bastian Czogalla, Fabian Trillsch, Sven Mahner, Doris Mayr, Elisa Schmoeckel, Nina Ditsch
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2698 (2022)
Background: Since the most well-known function of thyroid hormone receptors (TRs) relies on their ability to act as ligand-activated transcription factors, their subcellular localization has been recognized to be relevant for their biological meaning
Externí odkaz:
https://doaj.org/article/84dc7de1d0ca48c0b525fe231ce9bac8
Autor:
Line Korsgaard Johnsen, Anna Hester Ver Loren van Themaat, Kit Melissa Larsen, Birgitte Klee Burton, William Frans Christiaan Baaré, Kathrine Skak Madsen, Merete Nordentoft, Hartwig Roman Siebner, Kerstin Jessica Plessen
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
Children, adolescents, and young adults with at least one first-degree relative [familial high-risk (FHR)] with either schizophrenia (SZ) or bipolar disorder (BD) have a one-in-two risk of developing a psychiatric disorder. Here, we review functional
Externí odkaz:
https://doaj.org/article/1503f6a022494e5b8650054b270fc239
Autor:
Eileen Deuster, Ivi Hysenaj, Maja Kahaly, Elisa Schmoeckel, Doris Mayr, Susanne Beyer, Thomas Kolben, Anna Hester, Fabian Kraus, Anca Chelariu-Raicu, Alexander Burges, Sven Mahner, Udo Jeschke, Fabian Trillsch, Bastian Czogalla
Publikováno v:
Cells, Vol 10, Iss 9, p 2337 (2021)
The platelet-activating factor receptor (PAFR) and its ligand (PAF) are important inflammatory mediators that are overexpressed in ovarian cancer. The receptor is an important player in ovarian cancer development. In this study, we aimed to evaluate
Externí odkaz:
https://doaj.org/article/fcf9a42f48fe4ba7a4a18d1a16d83e37