Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Anna Herrmannová"'
Autor:
Anna Herrmannová, Jan Jelínek, Klára Pospíšilová, Farkas Kerényi, Tomáš Vomastek, Kathleen Watt, Jan Brábek, Mahabub Pasha Mohammad, Susan Wagner, Ivan Topisirovic, Leoš Shivaya Valášek
Publikováno v:
eLife, Vol 13 (2024)
Protein synthesis plays a major role in homeostasis and when dysregulated leads to various pathologies including cancer. To this end, imbalanced expression of eukaryotic translation initiation factors (eIFs) is not only a consequence but also a drive
Externí odkaz:
https://doaj.org/article/86858da3f3d24ee1bcdd83771bd9fdc5
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103454- (2024)
Summary: Activating transcription factor 4 (ATF4) is a key player in the integrated stress response, whose expression is subject to tight translational control. Studying its stress-provoked induction, accompanied by the general translational shutdown
Externí odkaz:
https://doaj.org/article/ec47571144654d728002c7bfb6b548c9
Autor:
Anna M. Smirnova, Vladislava Hronová, Mahabub Pasha Mohammad, Anna Herrmannová, Stanislava Gunišová, Denisa Petráčková, Petr Halada, Štěpán Coufal, Michał Świrski, Justin Rendleman, Kristína Jendruchová, Maria Hatzoglou, Petra Beznosková, Christine Vogel, Leoš Shivaya Valášek
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 113976- (2024)
Summary: Activating transcription factor 4 (ATF4) is a master transcriptional regulator of the integrated stress response, leading cells toward adaptation or death. ATF4’s induction under stress was thought to be due to delayed translation reinitia
Externí odkaz:
https://doaj.org/article/0f04c695bf164ff7a96d9c1f5bcc5a53
Autor:
Leoš Valášek, Susan Wagner, Anna Herrmannová, Aurelio Teleman, Jonathan Bohlen, Thomas Preiss, Jan Jelínek
Publikováno v:
Nature Protocols. 17:2139-2187
Multiple aspects of mRNA translation are subject to regulation. Here we present a ribosome footprinting protocol to determine the location and composition of 40S and 80S ribosome complexes on endogenous mRNAs transcriptome-wide in vivo in yeast and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b005491fad1a44f42cfbc14824cceee
https://doi.org/10.1038/s41596-022-00708-4
https://doi.org/10.1038/s41596-022-00708-4
Autor:
Jakub Zeman, Darina Šikrová, Kristýna Poncová, Leoš Shivaya Valášek, Susan Wagner, Anna Herrmannová, Terezie Prilepskaja
Publikováno v:
Nucleic Acids Research
One of the key roles of the 12-subunit eukaryotic translation initiation factor 3 (eIF3) is to promote the formation of the 43S and 48S pre-initiation complexes (PICs). However, particular contributions of its individual subunits to these two critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b05327d388ca7ed34143b27a123767
https://doi.org/10.1093/nar/gkz1185
https://doi.org/10.1093/nar/gkz1185
Autor:
Leoš Shivaya Valášek, Will E Hinckley, Vladislava Hronová, Krzysztof J. Szkop, Daniel Sultanov, Ivan Topisirovic, Matthew Pressler, Zhaofeng Gao, Christine Vogel, Anna Herrmannová, Mahabub Pasha Mohammad, Maria Hatzoglou, Kristina Allgoewer, Shuvadeep Maity, Justin Rendleman, Amy Lei, Ola Larsson
Translation includes initiation, elongation, and termination, followed by ribosome recycling. We characterize a new sequence element in 5’ untranslated regions that consists of an adjacent start and stop codon and thereby excludes elongation. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::048334ae1e9dcf7dbf0c6892cf4e90d4
https://doi.org/10.1101/2021.07.26.453809
https://doi.org/10.1101/2021.07.26.453809
Autor:
Kristýna Poncová, Stanislava Gunišová, Anna Herrmannová, Leoš Shivaya Valášek, Jakub Zeman, Susan Wagner, Jinsheng Dong, Myrte Esmeralda Jansen, Petra Beznosková
Publikováno v:
Nucleic Acids Research
Ribosome was long considered as a critical yet passive player in protein synthesis. Only recently the role of its basic components, ribosomal RNAs and proteins, in translational control has begun to emerge. Here we examined function of the small ribo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1688198ca71a410a542e78f197c3f906
https://doi.org/10.1093/nar/gkz929
https://doi.org/10.1093/nar/gkz929
Autor:
Anna Herrmannová, David Potěšil, Christos Michailidis, Zbyněk Zdráhal, David Honys, Jana Feciková, Leoš Shivaya Valášek, Jan Fíla, Said Hafidh, Karel Müller, Till Ischebeck
Publikováno v:
Plant Physiology. 178:258-282
Reproduction success in angiosperm plants depends on robust pollen tube growth through the female pistil tissues to ensure successful fertilization. Accordingly, there is an apparent evolutionary trend to accumulate significant reserves during pollen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e34629baf05f5f5d162049fe3e3fa0
https://doi.org/10.1104/pp.18.00648
https://doi.org/10.1104/pp.18.00648
Autor:
Ross D. Hannan, Alan G. Hinnebusch, Nikolay E. Shirokikh, Thomas Preiss, Anna Herrmannová, Leoš Shivaya Valášek, Susan Wagner, Vladislava Hronová, Neelam Dabas Sen
SUMMARYTranslational control targeting mainly the initiation phase is central to the regulation of gene expression. Understanding all of its aspects requires substantial technological advancements. Here we modified yeast Translational Complex Profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580ab17258d7286fcbad4a652c333d70
https://doi.org/10.1101/806125
https://doi.org/10.1101/806125
Publikováno v:
RNA. 22:957-967
Nucleic acid sequence complementarity underlies many fundamental biological processes. Although first noticed a long time ago, sequence complementarity between mRNAs and ribosomal RNAs still lacks a meaningful biological interpretation. Here we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b12f6ba41224df24fa37f361d84bbce
https://doi.org/10.1261/rna.056119.116
https://doi.org/10.1261/rna.056119.116