Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Anna H Tran"'
Autor:
Gerald V Denis, Paola Sebastiani, Kimberly A Bertrand, Katherine J Strissel, Anna H Tran, Jaromir Slama, Nilton D Medina, Guillaume Andrieu, Julie R Palmer
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196755 (2018)
Obesity-driven Type 2 diabetes (T2D) is a systemic inflammatory condition associated with cardiovascular disease. However, plasma cytokines and tissue inflammation that discriminate T2D risk in African American women with obese phenotypes are not wel
Externí odkaz:
https://doaj.org/article/090ab09cab7443dab15e646cc0ed8e56
Kaplan-Meier curve to plot distant metastasis-free survival of 664 breast cancer patients was calculated from the Kaplan-Meier plotter database. Patients were subdivided into 'high expression' (BRD4high, JAG1high, n=332) and 'low expression' (BRD4low
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5989bff05577861535512bdf6b728e6d
https://doi.org/10.1158/0008-5472.22413609
https://doi.org/10.1158/0008-5472.22413609
(A) Heatmap representing relative expression of 46 genes involved in regulation of migration and invasion in response to BRD4 depletion in SUM149PT cells. Z scores are represented using a color code. Results for separate knockdown experiments were co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34707ade4d0517f39327eb02f4e712a5
https://doi.org/10.1158/0008-5472.22413612.v1
https://doi.org/10.1158/0008-5472.22413612.v1
The Supplemental Table 1 lists the qPCR primers used in this study. The Supplemental Table 2 lists the ChIP primers used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b63524e8c5cb07cdd6f295749b1be3c
https://doi.org/10.1158/0008-5472.22413603
https://doi.org/10.1158/0008-5472.22413603
The bromodomain and extraterminal (BET) proteins are epigenetic “readers” of acetylated histones in chromatin and have been identified as promising therapeutic targets in diverse cancers. However, it remains unclear how individual family members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a40ef46896bad4ff1b5d3bcb4f3e6ee
https://doi.org/10.1158/0008-5472.c.6508767.v1
https://doi.org/10.1158/0008-5472.c.6508767.v1
(A-C) Relative mRNA expression levels of BRD2 (A), BRD3 (B), and BRD4 (C) in scrambled siRNA control or BRD2-, BRD3-, BRD4-depleted MDA-MB-231 cells. Bars show means (plus minus) SEM of three independent experiments. Statistical analyses were perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279a34039a20f7791e87a5d25dd5b003
https://doi.org/10.1158/0008-5472.22413615.v1
https://doi.org/10.1158/0008-5472.22413615.v1
(A-C) Migration (left panels) and invasion (right panels) assays were conducted using MCF-7 cells under (A) BRD4 over-expression, (B) treatment with IL-6 (50 ng/ml for 24h), (C) BRD4 over-expression and treatment with DAPT (10 microM for 16 h). Bars
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303fe9f12b306fa4ca3125ce9aeb8060
https://doi.org/10.1158/0008-5472.22413606.v1
https://doi.org/10.1158/0008-5472.22413606.v1
(A) MTT assay showing viability of MDA-MB-231, SUM149PT and MCF-7 cells treated either with 400 nM (R)-JQ1 (filled symbol) or (S)-JQ1 (open symbol) for the indicated times. Dots represent means {plus minus} SEM of three independent experiments. Stati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d0bc8bcf5eed9bcdbd3cd621cd7423
https://doi.org/10.1158/0008-5472.22413618
https://doi.org/10.1158/0008-5472.22413618
Autor:
Guillaume Andrieu, Gerald V. Denis, Frank L. Lombardi, Katherine J. Strissel, Anna H. Tran, Julie R. Palmer, Paola Sebastiani
Publikováno v:
Obesity. 25:1916-1920
OBJECTIVE The principal objective of this investigation was to identify novel cytokine associations with BMI and type 2 diabetes (T2D). METHODS Cytokines were profiled from African American women with obesity who donated plasma to the Komen Tissue Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e3e35378d65452e4f4f060dfb4b8252
https://doi.org/10.1002/oby.21943
https://doi.org/10.1002/oby.21943
Publikováno v:
Cancer Research. 76:6555-6567
The bromodomain and extraterminal (BET) proteins are epigenetic “readers” of acetylated histones in chromatin and have been identified as promising therapeutic targets in diverse cancers. However, it remains unclear how individual family members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03193e773a3c61d19cf6ca433b1773f6
https://doi.org/10.1158/0008-5472.can-16-0559
https://doi.org/10.1158/0008-5472.can-16-0559