Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Anna Guinot"'
Detailed descriptions of the supplemental figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345c747a376c3f9e2be561c82c5ba4d0
https://doi.org/10.1158/0008-5472.22412249.v1
https://doi.org/10.1158/0008-5472.22412249.v1
Defining the molecular and cellular roots of lung cancer relapse after initial treatment remains an imperative to improve survival. Here we report that the lung stem cell marker Lgr6 becomes enriched in non–small cell lung cancer (NSCLC) cells duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b41590f9140b15b6478f0941100e903
https://doi.org/10.1158/0008-5472.c.6508400.v1
https://doi.org/10.1158/0008-5472.c.6508400.v1
Autor:
Caterina Mezzatesta, Martin Schrappe, Marketa Zaliova, Arend von Stackelberg, Cornelia Eckert, Yi Chien Tsai, Beat Bornhauser, Anna Guinot, Gunnar Cario, Denis M. Schewe, Luciana Vinti, Blerim Marovca, Franco Locatelli, Martin Stanulla, Jean-Pierre Bourquin, Silvia Jenni, Júlia Aguadé-Gorgorió, Liridon Abduli
Publikováno v:
Blood Cancer Journal
Blood Cancer Journal, Vol 10, Iss 6, Pp 1-11 (2020)
Blood Cancer Journal, Vol 10, Iss 6, Pp 1-11 (2020)
Despite rapid progress in genomic profiling in acute lymphoblastic leukemia (ALL), identification of actionable targets and prediction of response to drugs remains challenging. To identify specific vulnerabilities in ALL, we performed a drug screen u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf59fe2fc1f48e1f62c82e86c28466e
https://pubmed.ncbi.nlm.nih.gov/32591499
https://pubmed.ncbi.nlm.nih.gov/32591499
Autor:
Beat Bornhauser, Scott McComb, Caterina Mezzatesta, Silvia Jenni, Jean-Pierre Bourquin, Maria Pamela Dobay, Anna Guinot, Júlia Aguadé-Gorgorió, Martin Stanulla, Arend von Stackelberg, Liridon Abduli, Martin Schrappe, Gunnar Cario, Blerim Marovca, Cornelia Eckert
Publikováno v:
Blood Adv
Despite major advances in the treatment of patients with acute lymphoblastic leukemia in the last decades, refractory and/or relapsed disease remains a clinical challenge, and relapsed leukemia patients have an exceedingly dismal prognosis. Dysregula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a01b8c95089a4ba74af21b7cd81260d
Autor:
Holmfridur Hartmannsdottir, Beat Bornhauser, Pik Ki Chan, Scott McComb, Silvia Jenni, Maria Pamela Dobay, Jean-Pierre Bourquin, Anna Guinot
Publikováno v:
Science Advances
Caspase-3 and -7 are redundantly required to amplify the extrinsic and intrinsic apoptotic cascade in human leukemia.
Apoptosis is a complex multi-step process driven by caspase-dependent proteolytic cleavage cascades. Dysregulation of apoptosis
Apoptosis is a complex multi-step process driven by caspase-dependent proteolytic cleavage cascades. Dysregulation of apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4753fa8a50a21d1df09c9d589c51c8f
https://doi.org/10.1126/sciadv.aau9433
https://doi.org/10.1126/sciadv.aau9433
Publikováno v:
The Journal of Pathology. 239:365-373
The von Hippel-Lindau (VHL) tumour suppressor gene is bi-allelically inactivated in the majority of cases of clear cell renal cell carcinoma (ccRCC); however, Vhl knockout mouse models do not recapitulate human ccRCC, implying that additional mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df3490f2cc36db3ab6afc092acb28da7
https://doi.org/10.1002/path.4736
https://doi.org/10.1002/path.4736
Autor:
Roland H. Wenger, Sara Santambrogio, Ana Filipa Gonçalves, Ian J. Frew, David Hoogewijs, Miriam J. Schönenberger, Karen A. Nolan, Hugo M Marti, Anna Guinot, Aurelia Lelli
Publikováno v:
Hypoxia
Aurelia Lelli,1,2,* Karen A Nolan,1,2,* Sara Santambrogio,1,2 Ana Filipa Gonçalves,1,2 Miriam J Schönenberger,1,2 Anna Guinot,1,2 Ian J Frew,1,2 Hugo H Marti,3 David Hoogewijs,1,2,4 Roland H Wenger1,2 1Institute of Physiology and Zurich Center for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9d7185cd4ac7e575d705d48d05d66a
https://www.dovepress.com/induction-of-long-noncoding-rna-malat1-in-hypoxic-mice-peer-reviewed-artic
https://www.dovepress.com/induction-of-long-noncoding-rna-malat1-in-hypoxic-mice-peer-reviewed-artic
Publikováno v:
The Journal of pathology. 239(3)
The von Hippel-Lindau (VHL) tumour suppressor gene is bi-allelically inactivated in the majority of cases of clear cell renal cell carcinoma (ccRCC); however, Vhl knockout mouse models do not recapitulate human ccRCC, implying that additional mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d38d912f462b5cf1929037d21139e60c
https://pubmed.ncbi.nlm.nih.gov/27126173
https://pubmed.ncbi.nlm.nih.gov/27126173
Publikováno v:
The EMBO Journal. 31:3431-3441
The cellular and molecular mechanisms that control lung homeostasis and regeneration are still poorly understood. It has been proposed that a population of cells exists in the mouse lung with the potential to differentiate into all major lung bronchi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::142c5d5d142eb38b4ea375f1d2ef2ebf
https://doi.org/10.1038/emboj.2012.192
https://doi.org/10.1038/emboj.2012.192
Autor:
Anna Guinot, Matxalen Uriarte, Santiago Ramón-Maiques, Ignacio Fita, Alberto Marina, Vicente Rubio, Fernando Gil-Ortiz
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Carbamate kinase (CK) makes ATP from ADP and carbamoyl phosphate (CP) in the final step of the microbial fermentative catabolism of arginine, agmatine, and oxalurate/allantoin. Two previously reported CK structures failed to clarify CP binding and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f484073c20d9397097bb47d75a065d8
https://doi.org/10.1016/j.jmb.2010.02.038
https://doi.org/10.1016/j.jmb.2010.02.038