Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Anna Guastafierro"'
Autor:
Masahiro Shuda, Anna Guastafierro, Xuehui Geng, Yoko Shuda, Stephen M Ostrowski, Stefan Lukianov, Frank J Jenkins, Kord Honda, Stephen M Maricich, Patrick S Moore, Yuan Chang
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142329 (2015)
Merkel cell polyomavirus (MCV) causes the majority of human Merkel cell carcinomas (MCC) and encodes a small T (sT) antigen that transforms immortalized rodent fibroblasts in vitro. To develop a mouse model for MCV sT-induced carcinogenesis, we gener
Externí odkaz:
https://doaj.org/article/ee230b55f68646b08018e65853fa7d10
Autor:
Lindsay R Dresang, Anna Guastafierro, Reety Arora, Daniel Normolle, Yuan Chang, Patrick S Moore
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80543 (2013)
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer associated with high mortality. Merkel cell polyomavirus (MCV), discovered in 2008, is associated with ~80% of MCC. The MCV large tumor (LT) oncoprotein upregulates the cellular oncoprotein
Externí odkaz:
https://doaj.org/article/e7909d6eac544daa993c3a34efd7e948
Autor:
Lars Neumann, Verena Vondey, Maja Pizevska, Günter Krause, Michael Hallek, Anna Guastafierro, Elisa Göckeritz, Floyd Hassenrück
Publikováno v:
British journal of haematology. 178(6)
To elucidate their mechanism of action, inhibitors of Bruton tyrosine kinase (BTK) and resistant BTK mutants were employed to dissect target-dependent cellular functions. BTK-C481S and -T474I, expressed in Ramos and NALM-6 cells, maintained BTK auto-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a697629b680ad9bfa00e89617775761c
https://pubmed.ncbi.nlm.nih.gov/28573668
https://pubmed.ncbi.nlm.nih.gov/28573668
Autor:
Patrick S. Moore, Anna Guastafierro, Huichen Feng, Mamie Thant, Yuan Chang, John M. Kirkwood, Masahiro Shuda
Publikováno v:
Journal of Virological Methods. 187:6-14
Merkel cell carcinoma (MCC) is an aggressive skin cancer with a high mortality rate. The majority of MCC (70-80%) harbor clonally integrated Merkel cell polyomavirus (MCV) in the tumor genome and express viral T antigen oncoproteins. The characteriza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7935645a97a188ff8ec498076289223b
https://doi.org/10.1016/j.jviromet.2012.10.001
https://doi.org/10.1016/j.jviromet.2012.10.001
Autor:
Kathleen F. Richards, Patrick S. Moore, Masahiro Shuda, Anna Guastafierro, Tuna Toptan, Yuan Chang
Publikováno v:
The Journal of general virology. 96(12)
Merkel cell polyomavirus (MCV) is clonally integrated in over 80 % of Merkel cell carcinomas and mediates tumour development through the expression of viral oncoproteins, the large T (LT) and small T antigens (sT). Viral integration is associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244fcd48cc9df1b7dac6b56fd66a0e1f
https://pubmed.ncbi.nlm.nih.gov/26385761
https://pubmed.ncbi.nlm.nih.gov/26385761
Autor:
Anna Guastafierro, Daniel P. Normolle, Yuan Chang, Lindsay R. Dresang, Reety Arora, Patrick S. Moore
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e80543 (2013)
PLoS ONE, Vol 8, Iss 11, p e80543 (2013)
Merkel cell carcinoma (MCC) is a neuroendocrine skin cancer associated with high mortality. Merkel cell polyomavirus (MCV), discovered in 2008, is associated with ~80% of MCC. The MCV large tumor (LT) oncoprotein upregulates the cellular oncoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bad76c8d24e3e5387f4eb9645e1966
https://pubmed.ncbi.nlm.nih.gov/24260412
https://pubmed.ncbi.nlm.nih.gov/24260412
Autor:
Laura L. Vollmer, Yanis L. Tolstov, Jeffrey L. Brodsky, Tuna Toptan, Alexander Dömling, Andreas Vogt, Daniel P. Normolle, Patrick S. Moore, Reety Arora, Anna Guastafierro, Yuan Chang, Masahiro Shuda
Publikováno v:
Journal of Clinical Oncology, 30(15). AMER SOC CLINICAL ONCOLOGY
ResearcherID
ResearcherID
8577 Background: MCC is an aggressive, chemoresistant skin cancer causing more deaths each year than chronic myelogenous leukemia. We discovered a new virus, Merkel cell polyomavirus (MCV), clonally integrated into ~80% of primary and metastatic MCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c907ef62de9ce78ef64fec181b3c2f1e
https://research.rug.nl/en/publications/c29e16ab-0d37-4390-bc69-6d2ac1878889
https://research.rug.nl/en/publications/c29e16ab-0d37-4390-bc69-6d2ac1878889
Autor:
Yanis L. Tolstov, Alexander Dömling, Laura L. Vollmer, Huichen Feng, Anna Guastafierro, Tuna Toptan, Daniel P. Normolle, Patrick S. Moore, Reety Arora, Yuan Chang, Jeffrey L. Brodsky, Masahiro Shuda, Andreas Vogt
Publikováno v:
Science translational medicine. 4(133)
Merkel cell polyomavirus (MCV) causes ~80% of primary and metastatic Merkel cell carcinomas (MCCs). By comparing digital transcriptome subtraction deep-sequencing profiles, we found that transcripts of the cellular survivin oncoprotein [BIRC5a (bacul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b296b834ebea43e1b9aee889a6845bcf
https://pubmed.ncbi.nlm.nih.gov/22572880
https://pubmed.ncbi.nlm.nih.gov/22572880
Autor:
Masahiro Shuda, Gretchen Meinke, Anna Guastafierro, Hyun Jin Kwun, Andrew Bohm, Patrick S. Moore, Yuan Chang
Publikováno v:
Journal of virology. 83(23)
Merkel cell polyomavirus (MCV) is a recently discovered human polyomavirus causing the majority of human Merkel cell carcinomas. We mapped a 71-bp minimal MCV replication core origin sufficient for initiating eukaryotic DNA replication in the presenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac44db264e455ec15c2dbb2d035fc16
https://pubmed.ncbi.nlm.nih.gov/19759150
https://pubmed.ncbi.nlm.nih.gov/19759150