TrpM, a Small Protein Modulating Tryptophan Biosynthesis and Morpho-Physiological Differentiation in Streptomyces coelicolor A3(2).

Autor: Emilia Palazzotto, Giuseppe Gallo, Giovanni Renzone, Anna Giardina, Alberto Sutera, Joohee Silva, Celinè Vocat, Luigi Botta, Andrea Scaloni, Anna Maria Puglia

Publikováno v: PLoS ONE, Vol 11, Iss 9, p e0163422 (2016)

In the model actinomycete Streptomyces coelicolor A3(2), small open reading frames encoding proteins with unknown functions were identified in several amino acid biosynthetic gene operons, such as SCO2038 (trpX) in the tryptophan trpCXBA locus. In th

Externí odkaz: https://doaj.org/article/5795f40eda504623a88847ab48ac1589

Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024

Autor: Tilmann Weber, A. Russo, Giovanni Spinelli, Anna Giardina, E. Palazzotto, Margherita Sosio, Rosa Alduina, Giuseppe Gallo, Simona Arena, Anna Maria Puglia, Fabio Sangiorgi, Andrea Scaloni, Giovanni Renzone, T. Faddetta, Paolo Monciardini

Publikováno v: BMC Genomics
Gallo, G, Renzone, G, Palazzotto, E, Monciardini, P, Arena, S, Faddetta, T, Giardina, A, Alduina, R, Weber, T, Sangiorgi, F, Russo, A, Spinelli, G, Sosio, M, Scaloni, A & Puglia, A M 2016, ' Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024 ', B M C Genomics, vol. 17, no. 42 . https://doi.org/10.1186/s12864-016-2369-z
BMC genomics 17 (2016). doi:10.1186/s12864-016-2369-z
info:cnr-pdr/source/autori:Gallo G.; Renzone G.; Palazzotto E.; Monciardini P.; Arena S.; Faddetta T.; Giardina A.; Alduina R.; Weber T.; Sangiorgi F.; Russo A.; Spinelli G.; Sosio M.; Scaloni A.; Puglia A.M./titolo:Elucidating the molecular physiology of lantibiotic NAI-107 production in Microbispora ATCC-PTA-5024/doi:10.1186%2Fs12864-016-2369-z/rivista:BMC genomics/anno:2016/pagina_da:/pagina_a:/intervallo_pagine:/volume:17

Background The filamentous actinomycete Microbispora ATCC-PTA-5024 produces the lantibiotic NAI-107, which is an antibiotic peptide effective against multidrug-resistant Gram-positive bacteria. In actinomycetes, antibiotic production is often associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf99bbe1f04dc34e4a036aac761d51df
https://pubmed.ncbi.nlm.nih.gov/26754974

Inorganic phosphate is a trigger factor for Microbispora sp. ATCC-PTA-5024 growth and NAI-107 production

Autor: Margherita Sosio, Rosa Alduina, Paolo Monciardini, Anna Maria Puglia, Anna Giardina, Giuseppe Gallo

Publikováno v: Microbial Cell Factories

Background NAI-107, produced by the actinomycete Microbispora sp. ATCC-PTA-5024, is a promising lantibiotic active against Gram-positive bacteria and currently in late preclinical-phase. Lantibiotics (lanthionine-containing antibiotics) are ribosomal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f67de2f98ab22ee68bc42af9da88a6
http://hdl.handle.net/10447/100759

Two heterologously expressed Planobispora rosea proteins cooperatively induce Streptomyces lividans thiostrepton uptake and storage from the extracellular medium

Autor: Valentina Di Caro, Roderich D. Süssmuth, Elvira M. Gottardi, Anna Giardina, Anna Maria Puglia, Rosa Alduina

Publikováno v: Microbial Cell Factories
Microbial Cell Factories, Vol 9, Iss 1, p 44 (2010)

Background A bacterial artificial chromosomal library of Planobispora rosea, a genetically intractable actinomycete strain, was constructed using Escherichia coli-Streptomyces artificial chromosome (ESAC) and screened for the presence of genes known

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf52685b66c4395aca4693a4742264c7
https://pubmed.ncbi.nlm.nih.gov/20534129