Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Anna Garuti"'
Autor:
Lorenzo Ferrando, Andrea Vingiani, Anna Garuti, Claudio Vernieri, Antonino Belfiore, Luca Agnelli, Gianpaolo Dagrada, Diana Ivanoiu, Giuseppina Bonizzi, Elisabetta Munzone, Luana Lippolis, Martina Dameri, Francesco Ravera, Marco Colleoni, Giuseppe Viale, Luca Magnani, Alberto Ballestrero, Gabriele Zoppoli, Giancarlo Pruneri
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010563 (2023)
BackgroundPrevious studies have provided a comprehensive picture of genomic alterations in primary and metastatic Hormone Receptor (HR)-positive, Human Epidermal growth factor Receptor 2 (HER2)-negative breast cancer (HR+ HER2- BC). However, the evol
Externí odkaz:
https://doaj.org/article/14b422e7ad2742c09e052fbd82eff010
Autor:
Claudia Winkler, Matthew King, Julie Berthe, Domenico Ferraioli, Anna Garuti, Federica Grillo, Jaime Rodriguez-Canales, Lorenzo Ferrando, Nicolas Chopin, Isabelle Ray-Coquard, Oona Delpuech, Darawan Rinchai, Davide Bedognetti, Alberto Ballestrero, Elisabetta Leo, Gabriele Zoppoli
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Large independent analyses on cancer cell lines followed by functional studies have identified Schlafen 11 (SLFN11), a putative helicase, as the strongest predictor of sensitivity to DNA-damaging agents (DDAs), including platinum. However, its role a
Externí odkaz:
https://doaj.org/article/9b2a39fd1fd14e9b814ef38b204034e0
Autor:
Edoardo Isnaldi, Anna Garuti, Gabriella Cirmena, Stefano Scabini, Edoardo Rimini, Lorenzo Ferrando, Michela Lia, Roberto Murialdo, Lucia Tixi, Enrico Carminati, Andrea Panaro, Maurizio Gallo, Federica Grillo, Luca Mastracci, Lazzaro Repetto, Roberto Fiocca, Emanuele Romairone, Gabriele Zoppoli, Alberto Ballestrero
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background Over the past few years, next-generation sequencing (NGS) has become reliable and cost-effective, and its use in clinical practice has become a reality. A relevant role for NGS is the prediction of response to anti-EGFR agents in
Externí odkaz:
https://doaj.org/article/35769548e3cf45e59736d555324db447
Autor:
Barbara Cardinali, Giuseppa De Luca, Roberta Tasso, Simona Coco, Anna Garuti, Giulia Buzzatti, Andrea Sciutto, Luca Arecco, Federico Villa, Franca Carli, Daniele Reverberi, Rodolfo Quarto, Mariella Dono, Lucia Del Mastro
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 6320 (2022)
The study of circulating cancer-derived components (circulome) is considered the new frontier of liquid biopsy. Despite the recognized role of circulome biomarkers, their comparative molecular profiling is not yet routine. In advanced breast cancer (
Externí odkaz:
https://doaj.org/article/76545ccb24dd4083b5ef181329da8ec7
Autor:
Lorenzo Ferrando, Gabriella Cirmena, Anna Garuti, Stefano Scabini, Federica Grillo, Luca Mastracci, Edoardo Isnaldi, Ciro Marrone, Roberta Gonella, Roberto Murialdo, Roberto Fiocca, Emanuele Romairone, Alberto Ballestrero, Gabriele Zoppoli
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0226595 (2020)
Standard treatment for locally advanced rectal adenocarcinoma (LARC) includes a combination of chemotherapy with pyrimidine analogues, such as capecitabine, and radiation therapy, followed by surgery. Currently no clinically useful genomic predictors
Externí odkaz:
https://doaj.org/article/532f94825006425caaa01ce532cbf54e
Autor:
Gabriele Zoppoli, Anna Garuti, Gabriella Cirmena, Ludovica Verdun di Cantogno, Cristina Botta, Maurizio Gallo, Domenico Ferraioli, Enrico Carminati, Paola Baccini, Monica Curto, Piero Fregatti, Edoardo Isnaldi, Michela Lia, Roberto Murialdo, Daniele Friedman, Anna Sapino, Alberto Ballestrero
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-12 (2017)
Abstract Background Immunohistochemistry (IHC) and fluorescent-in situ hybridization (FISH) are standard methods to assess human epidermal growth factor receptor 2 (HER2) status in breast cancer (BC) patients. Real-time quantitative polymerase-chain-
Externí odkaz:
https://doaj.org/article/cf6c31feb9ac4d7694b7f812bc417b07
Autor:
Giuseppa De Luca, Barbara Cardinali, Lucia Del Mastro, Sonia Lastraioli, Franca Carli, Manlio Ferrarini, George A. Calin, Anna Garuti, Carlotta Mazzitelli, Simona Zupo, Mariella Dono
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4364 (2020)
Molecular characterization of Circulating Tumor Cells (CTCs) is still challenging, despite attempts to minimize the drawbacks of Whole Genome Amplification (WGA). In this paper, we propose a Next-Generation Sequencing (NGS) optimized protocol based o
Externí odkaz:
https://doaj.org/article/242def411f0648f19b83de0eeef28d5e
Autor:
Chiara Barisione, Silvano Garibaldi, Anna Lisa Furfaro, Mariapaola Nitti, Daniela Palmieri, Mario Passalacqua, Anna Garuti, Daniela Verzola, Alessia Parodi, Pietro Ameri, Paola Altieri, Patrizia Fabbi, Pier Francesco Ferrar, Claudio Brunelli, Violeta Arsenescu, Manrico Balbi, Domenico Palombo, Giorgio Ghigliotti
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149276 (2016)
OBJECTIVE:The uremic toxin Indoxyl-3-sulphate (IS), a ligand of Aryl hydrocarbon Receptor (AhR), raises in blood during early renal dysfunction as a consequence of tubular damage, which may be present even when eGFR is normal or only moderately reduc
Externí odkaz:
https://doaj.org/article/df9b062c73184a7380123cf8e5afe9e1
Autor:
Paola Altieri, Chiara Barisione, Edoardo Lazzarini, Anna Garuti, Gian Paolo Bezante, Marco Canepa, Paolo Spallarossa, Carlo Gabriele Tocchetti, Sveva Bollini, Claudio Brunelli, Pietro Ameri
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 1 (2016)
BackgroundChronic cardiotoxicity is less common in male than in female patients receiving doxorubicin and other anthracyclines at puberty and adolescence. We hypothesized that this sex difference might be secondary to distinct activities of sex hormo
Externí odkaz:
https://doaj.org/article/67d0fb22b0b8492b8204b08f6a22c4bb
Autor:
Paola Altieri, Paolo Spallarossa, Chiara Barisione, Silvano Garibaldi, Anna Garuti, Patrizia Fabbi, Giorgio Ghigliotti, Claudio Brunelli
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46126 (2012)
Senescence and apoptosis are two distinct cellular programs that are activated in response to a variety of stresses. Low or high doses of the same stressor, i.e., the anticancer drug doxorubicin, may either induce apoptosis or senescence, respectivel
Externí odkaz:
https://doaj.org/article/7fd83d493d4a468a9b55668dd81322a2