Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Anna Gaponova"'
Autor:
Marine Berquez, Zhiyong Chen, Beatrice Paola Festa, Patrick Krohn, Svenja Aline Keller, Silvia Parolo, Mikhail Korzinkin, Anna Gaponova, Endre Laczko, Enrico Domenici, Olivier Devuyst, Alessandro Luciani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Differentiation is critical for cell fate decisions, but the signals involved remain unclear. The kidney proximal tubule (PT) cells reabsorb disulphide-rich proteins through endocytosis, generating cystine via lysosomal proteolysis. Here we
Externí odkaz:
https://doaj.org/article/11a5f48d3b2345418cf8893bc3e0feb9
Autor:
Ekaterina Antonova, Olga Glazova, Anna Gaponova, Aykaz Eremyan, Svetlana Zvereva, Natalya Grebenkina, Natalya Volkova, Pavel Volchkov
Publikováno v:
F1000Research, Vol 7 (2018)
Background: CRISPR/Cas9 system is becoming the dominant genome editing tool in a variety of organisms. CRISPR/Cas9 mediated knock out has been demonstrated both in chicken cell lines and in chicken germ cells that served to generate genetically modif
Externí odkaz:
https://doaj.org/article/b92cd04bb44641318924852b06f771f4
Autor:
Ekaterina Antonova, Olga Glazova, Anna Gaponova, Aykaz Eremyan, Natalya Grebenkina, Svetlana Zvereva, Natalya Volkova, Pavel Volchkov
Publikováno v:
F1000Research, Vol 7 (2018)
Background: Influenza virus can cause both seasonal infections and unpredictable pandemics. Rapidly evolving avian H5N1 and H7N9 viruses have a potential pandemic threat for humans. Since avian Influenza can be transmitted by domestic birds, serving
Externí odkaz:
https://doaj.org/article/8a2c8beaaefc4653b74a4c2b6a602996
Autor:
Harvey Hensley, Meghan C. Kopp, Anna A. Kiseleva, Ilya G. Serebriiskii, Anna Gaponova, Anna S. Nikonova, Alexander Y. Deneka, Erica A. Golemis, Douglas B. Flieder
Publikováno v:
Cancer Res
Non–small cell lung cancer (NSCLC) is the most common cancer worldwide. With overall 5-year survival estimated at Significance: This study demonstrates a novel role for the scaffolding protein NEDD9 in regulating LKB1-AMPK signaling in early stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a5ecba2ca3df4ec826d1f5047518687
https://europepmc.org/articles/PMC8277748/
https://europepmc.org/articles/PMC8277748/
Autor:
David A. Proia, Anna S. Nikonova, Kelly E. Duncan, Natalya Skobeleva, Vladimir Khazak, Anna Gaponova, Alexander E. Kudinov, Alexander Y. Deneka, Meghan C. Kopp, Erica A. Golemis, Kathy Q. Cai, Yanis Boumber, James S. Duncan, Brian L. Egleston, Luisa Shin Ogawa
Publikováno v:
Clinical Cancer Research. 22:5120-5129
Purpose: Small cell lung cancer (SCLC) is a highly aggressive disease representing 12% to 13% of total lung cancers, with median survival of Experimental Design: To avoid DLT for useful cytotoxic agents, the recently developed drug STA-8666 combines
Autor:
Pavel Volchkov, N. A. Volkova, E. N. Antonova, Svetlana Zvereva, Anna Gaponova, Olga Glazova, Natalya Grebenkina, Aykaz Eremyan
Publikováno v:
F1000Research
Background: Influenza virus can cause both seasonal infections and unpredictable pandemics. Rapidly evolving avian H5N1 and H7N9 viruses have a potential pandemic threat for humans. Since avian Influenza can be transmitted by domestic birds, serving
Autor:
E. N. Antonova, Pavel Volchkov, Natalya Grebenkina, N. A. Volkova, Aykaz Eremyan, Svetlana Zvereva, Anna Gaponova, Olga Glazova
Publikováno v:
F1000Research
Background: CRISPR/Cas9 system is becoming the dominant genome editing tool in a variety of organisms. CRISPR/Cas9 mediated knock out has been demonstrated both in chicken cell lines and in chicken germ cells that served to generate genetically modif
Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD)
Autor:
David A. Proia, Ilya G. Serebriiskii, Harvey Hensley, Erica A. Golemis, Meghan C. Kopp, Alexander Y. Deneka, Tamina Seeger-Nukpezah, Vladislav Korobeynikov, Anna S. Nikonova, Anna A. Kiseleva, Anna Gaponova, Stefan Somlo
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(5)
Autosomal-dominant polycystic kidney disease (ADPKD) is associated with progressive formation of renal cysts, kidney enlargement, hypertension, and typically end-stage renal disease. In ADPKD, inherited mutations disrupt function of the polycystins (
Publikováno v:
Gene. 567:1-11
Cancer progression requires a significant reprogramming of cellular signaling to support the essential tumor-specific processes that include hyperproliferation, invasion (for solid tumors) and survival of metastatic colonies. NEDD9 (also known as Cas
Autor:
Anna Gaponova, Meghan C. Kopp, Anna S. Nikonova, Leora Haber, Erica A. Golemis, Alexander Y. Deneka
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0176747 (2017)
PLoS ONE, Vol 12, Iss 4, p e0176747 (2017)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide, with a 5-year survival of only ~16%. Potential strategies to address NSCLC mortality include improvements in early detection and prevention, and development of new the