Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Anna Galkin"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/641ceffdbc544edc932193e565ae7229
Autor:
Laura Carter, Andrea Wang-Gillam, Johanna Bendell, Wungki Park, Wells Messersmith, Drew Rasco, Lei Zhou, Jean-Marie Bruey, Beatrice Ferguson, Jakob Dupont, Marya Chaney, Johann De Bono, David Nickle, Anna Galkin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/4c3856eeaeb64d86ae0c6a78be6a0f14
Autor:
Zhihong Huang, Jennifer Shaffer, Badry Bursulaya, Anna Galkin, Rie Kikkawa, Yelena Sarkisova, Su Hua, John Tellew, Yang Yang, Paul Vincent Rucker, Robert Epple, Jiqing Jiang, Nanxin Li, Chianelli Donatella, Jason Roland, Lintong Li, Sergio Briones, Casey J. N. Mathison, Valentina Molteni, Jacqueline Kinyamu-Akunda, Mu-Yun Gao, John Nelson, Christian C. Lee, Yun Feng Xie, Shailaja Kasibhatla, Chun Li
Publikováno v:
ACS Med Chem Lett
[Image: see text] The selective inhibition of RET kinase as a treatment for relevant cancer types including lung adenocarcinoma has garnered considerable interest in recent years and prompted a variety of efforts toward the discovery of small-molecul
Autor:
Bedrich Eckhardt, Kellie Mouchemore, Yang Liao, Wei Shi, Francesca Mercuri, Phil Kearney, Robin Anderson, Anna Galkin
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Xiuting Liu, Graham Hogg, Chong Zuo, John Baer, Varintra Lander, Liang Kang, Nicholas Borcherding, Brett Knolhoff, Robin Osterhout, Anna Galkin, Jean Bruey, Laura Carter, Cedric Mpoy, Julie Schwarz, Haeseong Park, Vineet Gupta, David DeNardo
Publikováno v:
Cancer Research. 83:5964-5964
Chronic activation of inflammatory pathways and suppressed interferon signaling are hallmarks of myeloid cells in immunosuppressive tumors that drive poor responsiveness to conventional and immune therapies. Previous studies have identified agonistic
Autor:
Badry Bursulaya, Nanxin Li, Yang Yang, Chianelli Donatella, John Nelson, Casey J. N. Mathison, Valentina Molteni, Sergio Briones, Chun Li, Shailaja Kasibhatla, Christian C. Lee, Jason Roland, Zhihong Huang, Jiqing Jiang, Anna Galkin, John Tellew, Robert Epple, Jacqueline Kinyamu-Akunda, Yelena Sarkisova, Mu-Yun Gao, Rie Kikkawa, Lintong Li, Su Hua, Paul Vincent Rucker, Jennifer Shaffer, Yun Feng Xie
Publikováno v:
ACS Medicinal Chemistry Letters. 11:558-565
RET (REarranged during Transfection) kinase gain-of-function aberrancies have been identified as potential oncogenic drivers in lung adenocarcinoma, along with several other cancer types, prompting the discovery and assessment of selective inhibitors
Autor:
Anna Galkin, Ravikumar Sitapara, Bryan Clemons, Eduardo Garcia, Michael Kennedy, David Guimond, Laura L. Carter, Ashley Douthitt, Robin Osterhout, Aneta Gandjeva, Deborah Slee, Luisa Salter-Cid, Rubin M. Tuder, Lawrence S. Zisman
Publikováno v:
The European respiratory journal. 60(6)
BackgroundSignalling through platelet-derived growth factor receptor (PDGFR), colony-stimulating factor 1 receptor (CSF1R) and mast/stem cell growth factor receptor kit (c-KIT) plays a critical role in pulmonary arterial hypertension (PAH). We examin
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 8 (2021)
Resistance to immune checkpoint inhibitors (ICI) and other anticancer therapies is often associated with the accumulation of myeloid-derived suppressor cells (MDSCs) and tumor-associated macrophages (TAMs) in the tumor microenvironment (TME). Therefo
Autor:
Wungki Park, Jean-Marie Bruey, Johanna C. Bendell, Andrea Wang-Gillam, Laura L. Carter, Lei Zhou, David C. Nickle, Jakob Dupont, Drew W. Rasco, Anna Galkin, Marya F. Chaney, Wells A. Messersmith, Johann S. de Bono, Beatrice Ferguson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background GB1275 is a first-in-class CD11b modulator in development as monotherapy and in combination with pembrolizumab or chemotherapy for the treatment of advanced solid tumors. Nonclinical data show that GB1275 reduced influx of tumor-associated
Autor:
Luisa Salter-Cid, Eduardo Garcia, Debbie Slee, M. L. Kennedy, Anna Galkin, Bryan Clemons, Ravi Sitapara, Laura L. Carter, Larry Zisman
Publikováno v:
Pulmonary hypertension.
Background: PAH is characterized by vascular remodeling, increased pulmonary arterial pressure (PAP) and right ventricular hypertrophy. Dysregulation of BMPR2 signaling is linked to hereditary and idiopathic forms of PAH. PDGF signaling plays an impo