Výsledky vyhledávání - "Anna Fila-Danilow"

Association of HSPA1B Polymorphisms with Paranoid Schizophrenia in a Polish Population

Autor: Aleksander Owczarek, Jan Kowalski, Malgorzata Kowalczyk, Wojciech Merk, Monika Paul-Samojedny, Piotr Choręza, Anna Fila-Danilow, Krzysztof Kucia, Renata Suchanek-Raif

Publikováno v: National Information Processing Institute
Neuromolecular Medicine

This study aimed to find the potential association betweenHSPA1Bpolymorphisms and risk of paranoid schizophrenia, clinical variables of the disease, and suicidal behavior. A total of 901 unrelated Polish subjects of Caucasian origin (377 schizophreni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243db092fe09d42ad6942df4051271a2
https://doi.org/10.1007/s12017-019-08575-1

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Effect of apigenin, kaempferol and resveratrol on the gene expression and protein secretion of tumor necrosis factor alpha (TNF-α) and interleukin-10 (IL-10) in RAW-264.7 macrophages

Autor: Monika Paul-Samojedny, Malgorzata Kowalczyk, Anna Fila-Danilow, Renata Suchanek-Raif, Paulina Borkowska, Marta Palacz-Wrobel, Jan Kowalski

Publikováno v: Biomedicine & Pharmacotherapy. 93:1205-1212

Polyphenols such as apigenin, kaempferol or resveratrol are typically found in plants, including fruits, vegetables, herbs and spices, which have a wide range of biological functions such as antioxidative, anti-inflammatory, vasodilative, anticoagula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b62f9ce99082302916c399a10b603e
https://doi.org/10.1016/j.biopha.2017.07.054

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Knockdown of AKT3 and PI3KCA by RNA interference changes the expression of the genes that are related to apoptosis and autophagy in T98G glioblastoma multiforme cells

Autor: Anna Fila-Danilow, Monika Paul-Samojedny, Malgorzata Kowalczyk, Renata Suchanek-Raif, Paulina Borkowska, Adam Pudełko, Jan Kowalski

Publikováno v: Pharmacological Reports. 67:1115-1123

Glioblastoma multiforme (GBM) is the most malignant and invasive human brain tumor and it is characterized by a poor prognosis and short survival time. The PI3K/AKT/PTEN signaling pathway plays a crucial role in GBM development and it is connected wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5138d74a22414f02ff26231c2cb4b324
https://doi.org/10.1016/j.pharep.2015.04.012

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Affect of antidepressants on the in vitro differentiation of rat bone marrow mesenchymal stem cells into neuronal cells

Autor: Paulina Borkowska, Anna Fila-Danilow, Anna M. Bielecka, Monika Paul-Samojedny, Malgorzata Kowalczyk, Jan Kowalski, Joanna Kowalska

Publikováno v: European Journal of Pharmaceutical Sciences. 73:81-87

Background Bone marrow is a valuable source of mesenchymal stem cells (MSCs) that can be used in regenerative medicine. MSCs are able to differentiate into cells from all three germ layers under specific conditions. The aim of the current work was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acff9b0bdfee9be8352323cbd94af67
https://doi.org/10.1016/j.ejps.2015.03.016

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The influence of TSA and VPA on the in vitro differentiation of bone marrow mesenchymal stem cells into neuronal lineage cells: Gene expression studies

Autor: Malgorzata Kowalczyk, Monika Paul-Samojedny, Anna Fila-Danilow, Jan Kowalski, Paulina Borkowska

Publikováno v: Scopus-Elsevier
Europe PubMed Central
Postępy Higieny i Medycyny Doświadczalnej, Vol 71, Iss 1, Pp 236-242 (2017)

Introduction: Epigenetic mechanisms regulate the transcription of genes, which can affect the differentiation of MSCs. The aim of the current work is to determine how the histone deacetylase inhibitors TSA and VPA affect the expression of neuronal li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202b06dc91baf44aad01ffe5014525b1
https://doi.org/10.5604/01.3001.0010.3809

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Association Study of Tumor Necrosis Factor Receptor 1 (TNFR1) Gene Polymorphisms with Schizophrenia in the Polish Population

Autor: Pawel Raif, Renata Suchanek-Raif, Jan Kowalski, Monika Paul-Samojedny, Malgorzata Kowalczyk, Anna Fila-Danilow, Krzysztof Kucia

Publikováno v: Mediators of Inflammation, Vol 2017 (2017)

Schizophrenia is a devastating mental disorder with undetermined aetiology. Previous research has suggested that dysregulation of proinflammatory cytokines and their receptors plays a role in developing schizophrenia. We examined the association of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96a4fe7ffeae6ffa63115411ae0ed4c

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Knockdown of the AKT3 (PKBγ), PI3KCA, and VEGFR2 genes by RNA interference suppresses glioblastoma multiforme T98G cells invasiveness in vitro

Autor: Jan Kowalski, Malgorzata Kowalczyk, Monika Paul-Samojedny, Adam Pudełko, Anna Fila-Danilow, Renata Suchanek-Raif, Paulina Borkowska

Publikováno v: Tumor Biology. 36:3263-3277

Glioblastoma multiforme (GBM) is the most common primary brain malignancy, having a very poor prognosis and is characterized by extensive brain invasion as well as resistance to the therapy. The phosphoinositide 3-kinase (PI3K)/Akt/PTEN signaling pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe798595399d4d8cb0de99df22ebc7b
https://doi.org/10.1007/s13277-014-2955-0

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Knockdown ofAKT3(PKBγ) andPI3KCASuppresses Cell Viability and Proliferation and Induces the Apoptosis of Glioblastoma Multiforme T98G Cells

Autor: Aleksander Owczarek, Renata Suchanek, Malgorzata Kowalczyk, Grzegorz Machnik, Adam Pudełko, Anna Fila-Danilow, Monika Paul-Samojedny, Paulina Borkowska, Jan Kowalski

Publikováno v: BioMed Research International, Vol 2014 (2014)
BioMed Research International

Glioblastoma multiforme (GBM) is the most malignant and invasive human brain tumor that is difficult to treat and has a very poor prognosis. Thus, new therapeutic strategies that target GBM are urgently needed. The PI3K/AKT/PTEN signaling pathway is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d61ca0a0cbba7ee36a95e5786416f0
https://doi.org/10.1155/2014/768181

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Heat shock protein 70 gene polymorphisms are associated with paranoid schizophrenia in the Polish population

Autor: Renata Suchanek, Anna Fila-Danilow, Krzysztof Kucia, Aleksander Owczarek, Monika Paul-Samojedny, Jan Kowalski, Paulina Borkowska, Malgorzata Kowalczyk

Publikováno v: Cell Stress and Chaperones. 19:205-215

HSP70 genes have been considered as promising schizophrenia candidate genes based on their protective role in the central nervous system under stress conditions. In this study, we analyzed the potential implication of HSPA1A +190G/C, HSPA1B +1267A/G,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96271f7deb91e6b8034de87c2245600f
https://doi.org/10.1007/s12192-013-0446-7

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Methylglyoxal (MGO) inhibits proliferation and induces cell death of human glioblastoma multiforme T98G and U87MG cells

Autor: Jan Kowalski, Renata Suchanek-Raif, Paulina Borkowska, Michał Zieliński, Anna Fila-Danilow, Adam Pudełko, Malgorzata Kowalczyk, Barbara Łasut, Monika Paul-Samojedny

Publikováno v: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 80

Glioblastoma multiforme (GBM) is the most malignant and invasive human brain tumor and it is characterized by a poor prognosis and short survival time. Current treatment strategies for GBM using surgery, chemotherapy and/or radiotherapy are ineffecti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffaec367365de9f96e9199a52ad912d9
https://pubmed.ncbi.nlm.nih.gov/27133062

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