Molecular and Cellular Aspects of Rhabdovirus Entry

Autor: Yves Gaudin, Aurélie A. V. Albertini, Anna Ferlin, Eduard Baquero

Publikováno v: Viruses, Vol 4, Iss 1, Pp 117-139 (2012)

Rhabdoviruses enter the cell via the endocytic pathway and subsequently fuse with a cellular membrane within the acidic environment of the endosome. Both receptor recognition and membrane fusion are mediated by a single transmembrane viral glycoprote

Externí odkaz: https://doaj.org/article/53c8cefb943a4de0bd0991378a91f6ba

Tissue Proteome of 2-Hydroxyacyl-CoA Lyase Deficient Mice Reveals Peroxisome Proliferation and Activation of ω-Oxidation

Autor: Youssef Khalil, Sara Carrino, Fujun Lin, Anna Ferlin, Heena V. Lad, Francesca Mazzacuva, Sara Falcone, Natalie Rivers, Gareth Banks, Danilo Concas, Carlos Aguilar, Andrew R. Haynes, Andy Blease, Thomas Nicol, Raya Al-Shawi, Wendy Heywood, Paul Potter, Kevin Mills, Daniel P. Gale, Peter T. Clayton

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 987, p 987 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 987

Peroxisomal fatty acid α-oxidation is an essential pathway for the degradation of β-carbon methylated fatty acids such as phytanic acid. One enzyme in this pathway is 2-hydroxyacyl CoA lyase (HACL1), which is responsible for the cleavage of 2-hydro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c88189b3e683c3cbd3ecd5300ea290
https://www.mdpi.com/1422-0067/23/2/987

Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1

Autor: David Wimbury, Jonathan Barratt, Xueqing Yu, Patricia Higgins, Karen Molyneux, Robert Kleta, Adam P. Levine, Horia Stanescu, Daniel P. Gale, Christopher P. Nelson, Anna Ferlin, Nilesh J. Samani, Peiran Yin, Ben Caplin

Publikováno v: Journal of the American Society of Nephrology. 28:2158-2166

IgA nephropathy (IgAN), an important cause of kidney failure, is characterized by glomerular IgA deposition and is associated with changes in O-glycosylation of the IgA1 molecule. Here, we sought to identify genetic factors contributing to levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4649f799f988b92cba44b51684ae8d6
https://doi.org/10.1681/asn.2016091043

Characterization of pH-sensitive molecular switches that trigger the structural transition of vesicular stomatitis virus glycoprotein from the postfusion state toward the prefusion state

Autor: Eduard Baquero, Jean Lepault, Anna Ferlin, Hélène Raux, Yves Gaudin

Publikováno v: Journal of virology. 88(22)

Vesicular stomatitis virus (VSV; the prototype rhabdovirus) fusion is triggered at low pH and mediated by glycoprotein G, which undergoes a low-pH-induced structural transition. A unique feature of rhabdovirus G is that its conformational change is r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3172bf068fac013f3a92bc19433f75c0
https://pubmed.ncbi.nlm.nih.gov/25210175