Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Anna F. Mkrtchyan"'
1
Akademický článek
Synthesis, Characterization, and Study of Catalytic Activity of Chiral Cu(II) and Ni(II) Salen Complexes in the α-Amino Acid C-α Alkylation Reaction
Autor: Anna S. Tovmasyan, Anna F. Mkrtchyan, Hamlet N. Khachatryan, Mary V. Hayrapetyan, Robert M. Hakobyan, Artavazd S. Poghosyan, Avetis H. Tsaturyan, Ela V. Minasyan, Victor I. Maleev, Vladimir A. Larionov, Armen G. Ayvazyan, Norio Shibata, Giovanni N. Roviello, Ashot S. Saghyan
Publikováno v: Molecules, Vol 28, Iss 3, p 1180 (2023)
A new family of Cu(II) and Ni(II) salen complexes was synthesized and fully characterized through various physicochemical methods. Their catalytic activity was evaluated in the phase transfer Cα-alkylation reaction of the Schiff bases of D,L-alanine
Externí odkaz: https://doaj.org/article/5b90462ad04541998c0eda0dba8608ed
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2
Akademický článek
Asymmetric Synthesis of Tailor-Made Amino Acids Using Chiral Ni(II) Complexes of Schiff Bases. An Update of the Recent Literature
Autor: Yupiao Zou, Jianlin Han, Ashot S. Saghyan, Anna F. Mkrtchyan, Hiroyuki Konno, Hiroki Moriwaki, Kunisuke Izawa, Vadim A. Soloshonok
Publikováno v: Molecules, Vol 25, Iss 12, p 2739 (2020)
Tailor-made amino acids are indispensable structural components of modern medicinal chemistry and drug design. Consequently, stereo-controlled preparation of amino acids is the area of high research activity. Over last decade, application of Ni(II) c
Externí odkaz: https://doaj.org/article/4f90547a8bae417490d47a6a8421b1f1
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3
Asymmetric Synthesis of Derivatives of Alanine via Michael Addition Reaction and their Biological Study
Autor: Anna F. Mkrtchyan, Anna S. Tovmasyan, Ani M. Paloyan, Armen S. Sargsyan, Hayarpi M. Simonyan, Lusine Yu. Sahakyan, Satenik Gh. Petrosyan, Liana A. Hayriyan, Tatev H. Sargsyan
Publikováno v: Synlett. 33:2013-2018
Ni(II) complex of the Schiff base of the chiral auxiliary (S)-2-N-(N′-benzylprolyl)aminobenzophenone (BPB) and dehydroalanine as the initial complex in the addition reaction was investigated. The obtained four new derivatives of α-alanine were inv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e5dbb0a44f15ef302ba9475330e4090
https://doi.org/10.1055/a-1941-2068
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5
Using the Ni-[(benzylprolyl)amino]benzophenone complex in the Glaser reaction for the synthesis of bis α-amino acids
Autor: Anna S. Tovmasyan, V. I. Maleev, Liana A. Hayriyan, Ani J. Karapetyan, Anna F. Mkrtchyan, Victor N. Khrustalev, Avetis H. Tsaturyan, Ashot S. Saghyan
Publikováno v: New Journal of Chemistry. 44:11927-11932
New different-structure enantiomerically enriched tailor-made (S)-α-amino acids were obtained through the cross-coupling reactions of Glaser. As the initial complexes, the Schiff base Ni(II) complexes of the chiral auxiliary (S)-BPB (BPB (N-benzyl p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac4b6684b79c617e384aec33654ac6fe
https://doi.org/10.1039/d0nj02072a
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7
Biological macromolecule binding and anticancer activity of synthetic alkyne-containing l-phenylalanine derivatives
Autor: Giovanni N. Roviello, Hayarpi M. Simonyan, Ashot S. Saghyan, Rosanna Palumbo, Agnieszka Belter, Anna F. Mkrtchyan, Marta A. Fik-Jaskółka, Valentina Roviello, Liana A. Hayriyan
Herein, we described the synthesis of two l-phenylalanines α-derivatized with a terminal alkyne moiety whose structures differed by phenyl ring halogen substitution (two o-Cl in 1 vs. one p-Br in 2) and investigated their effect on biological macrom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da05ca69e9456fc01596fc080c809efe
http://hdl.handle.net/11588/818951
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8
Synthesis of Optically Pure (S,E)-2-Amino-5-arylpent-4-enoic Acids by Heck Reactions of Nickel Complexes
Autor: Silvio Parpart, Ashot S. Saghyan, Anna F. Mkrtchyan, Peter Ehlers, Zorayr Z. Mardiyan, Peter Langer, Andranik Petrosyan
Publikováno v: Synlett. 29:793-798
Starting from commercially available building blocks a variety of enantiomerically pure (S)-2-amino-4-enoic acids has been synthesized by the Heck reaction using Ni-(S)-BPB {Nickel-N-[(S)-benzylprolyl]aminobenzophenone} as a chiral auxiliary. The rea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92d61a7c93d88d7a4a3a2554cdfea728
https://doi.org/10.1055/s-0037-1609094
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