Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Anna Eckers"'
Publikováno v:
Antioxidants & Redox Signaling. 26:630-644
Redox signaling is one of the key elements involved in cardiovascular diseases. Two important molecules are the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and the oxidoreductase thioredoxin-1 (Trx-1). Recent Advances: Dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f83aebf42d7c375743d3ac6b5d3f721d
https://doi.org/10.1089/ars.2016.6795
https://doi.org/10.1089/ars.2016.6795
Autor:
Regina Maushagen, Timo Gemoll, Martina Oberlaender, Giulia Faccinetti, Lena Figge, Ann-Kristin Kock-Schoppenhauer, Petra Duhm-Harbeck, Lina Niessen, Andreas Unger, Robert Wendlandt, Kowal, Justyna M., Anders Kristian Haakonsson, Christina Bober, Kai Diercks, Roman Nassutt, Robin Buescher, Nils Reimers, Hagen Schmal, Thomas Frahm, Anna Eckers, Julia Brilling, Torben Barington, Moustapha Kassem, Arndt-Peter Schulz, Habermann, Jens K.
Publikováno v:
Maushagen, R, Gemoll, T, Oberlaender, M, Faccinetti, G, Figge, L, Kock-Schoppenhauer, A-K, Duhm-Harbeck, P, Niessen, L, Unger, A, Wendlandt, R, Kowal, J M, Haakonsson, A K, Bober, C, Diercks, K, Nassutt, R, Buescher, R, Reimers, N, Schmal, H, Frahm, T, Eckers, A, Brilling, J, Barington, T, Kassem, M, Schulz, A-P & Habermann, J K 2018, ' International Harmonization and Standardization between Denmark and Germany: The German-Danish Interreg project BONEBANK ', Europe Biobank Week 2018, Antwerp, Belgium, 04/09/2018-07/09/2018 .
University of Southern Denmark
University of Southern Denmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9bac1bdd592f84e00f7e80fa19923084
https://portal.findresearcher.sdu.dk/da/publications/77ddddbf-f18f-4c51-8285-0a776da7648c
https://portal.findresearcher.sdu.dk/da/publications/77ddddbf-f18f-4c51-8285-0a776da7648c
Autor:
Joachim Altschmied, Sascha Jakob, Christian Heiss, Roberto Sansone, Miriam M. Cortese-Krott, Vanessa Brinkmann, Niloofar Ale-Agha, Natascia Ventura, Judith Haendeler, Anna Eckers, Charlotte Esser, Thomas Haarmann-Stemmann, Christine Goy
Publikováno v:
Scientific Reports
The ubiquitously expressed aryl hydrocarbon receptor (AhR) induces drug metabolizing enzymes as well as regulators of cell growth, differentiation and apoptosis. Certain AhR ligands promote atherosclerosis, an age-associated vascular disease. Therefo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300283199003de8f3c91d75e53bd34b2
https://doi.org/10.1038/srep19618
https://doi.org/10.1038/srep19618
Publikováno v:
Zeitschrift für Gerontologie und Geriatrie. 45:90-94
Reaktive Sauerstoffspezies (ROS) sind wichtige Signalmolekule in menschlichen Zellen. Physiologische Konzentrationen schutzen beispielsweise vor Apoptose und wirken als sekundarer Botenstoff in vielen verschiedenen Signalwegen. Die Redoxhomoostase st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae1d01282ecb5caa8dff2391dc55cdd
https://doi.org/10.1007/s00391-011-0277-z
https://doi.org/10.1007/s00391-011-0277-z
Autor:
Ingrit Hamann, Ayman O.S. El-Kadi, Lars-Oliver Klotz, Anwar Anwar-Mohamed, Elisabeth Sauerbier, Peter Schroeder, Charlotte Esser, Anna Eckers
Publikováno v:
Archives of Biochemistry and Biophysics. 516:138-145
FHRE-Luc is a promoter reporter construct that is widely used to assess the activity of FoxO (forkhead box, class O) transcription factors. We here demonstrate that this promoter construct responds to exposure of HepG2 human hepatoma cells to known a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc347a276572e3c94f23d01ea8bfcd35
https://doi.org/10.1016/j.abb.2011.10.006
https://doi.org/10.1016/j.abb.2011.10.006
Publikováno v:
BioMetals. 22:307-316
Nickel compounds may act as carcinogens, affecting both initiation and promotion stages of carcinogenesis due, in large parts, to their capability of inducing DNA damage and of modulating cellular signaling cascades known to affect cellular prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd420c54ad9392116c2a4d09b03ca99b
https://doi.org/10.1007/s10534-008-9167-2
https://doi.org/10.1007/s10534-008-9167-2
Autor:
Holger Steinbrenner, Mustafa Micoogullari, Helmut Sies, Silke De Spirt, Wilhelm Stahl, Carina Wehrend, Anna Eckers
Publikováno v:
Free radical biologymedicine. 91
Selenoenzymes and nuclear factor erythroid 2-related factor 2 (Nrf2)-regulated phase II enzymes comprise key components of the cellular redox and antioxidant systems, which show multiple interrelations. Deficiency of the micronutrient selenium (Se) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5971473541bed4361c41d0230474bda
https://pubmed.ncbi.nlm.nih.gov/26698667
https://pubmed.ncbi.nlm.nih.gov/26698667
Autor:
Anna Eckers, Tim-Christian Zschauer, Kerstin Kunze, Sascha Jakob, Joachim Altschmied, Judith Haendeler
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
In the endothelium, defense against oxidative stress as well as inhibition of apoptosis is mainly mediated by thioredoxin-1 (Trx-1). Trx-1 protein levels are reduced in aged endothelial cells (EC) in vitro and in vivo, leading to increased apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e5a469b9c0ae1b20baf15ff2af70365
https://doi.org/10.1161/atvb.32.suppl_1.a460
https://doi.org/10.1161/atvb.32.suppl_1.a460
Publikováno v:
Circulation Research. 109
Thioredoxin-1 (Trx-1) is one of the most important redox regulators in endothelial cells (EC). It is an oxidoreductase with anti-oxidative and anti-apoptotic properties. In EC not only the active site cysteines 32 and 35 but also the cysteine 69 are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1990aca4db443eef7e06e88a156ce57
https://doi.org/10.1161/res.109.suppl_1.ap047
https://doi.org/10.1161/res.109.suppl_1.ap047
Autor:
Philippe L. Walter, Dieter Schmoll, Lars-Oliver Klotz, Andreas Barthel, Anna Eckers, Helmut Sies, Andreas Kampkötter
Publikováno v:
Archives of biochemistry and biophysics. 454(2)
Cells respond to heavy metal stress by activating signaling cascades regulating cellular proliferation and survival. We here demonstrate that the anti-apoptotic kinase Akt is activated in HepG2 human hepatoma cells exposed to copper or zinc ions. Cu2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b090439f08cc508f9493ac71104cb67
https://pubmed.ncbi.nlm.nih.gov/16973122
https://pubmed.ncbi.nlm.nih.gov/16973122