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pro vyhledávání: '"Anna Eaton"'
Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology
Autor:
Annie M. Goettemoeller, Emmie Banks, Prateek Kumar, Viktor J. Olah, Katharine E. McCann, Kelly South, Christina C. Ramelow, Anna Eaton, Duc M. Duong, Nicholas T. Seyfried, David Weinshenker, Srikant Rangaraju, Matthew J. M. Rowan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Preventative treatment for Alzheimer’s Disease (AD) is dire, yet mechanisms underlying early regional vulnerability remain unknown. In AD, one of the earliest pathophysiological correlates to cognitive decline is hyperexcitability, which i
Externí odkaz:
https://doaj.org/article/472c8a45309c4ce99d27485c1bbd846b
Autor:
Emmie Banks, Claire-Anne Gutekunst, Geoffrey A. Vargish, Anna Eaton, Kenneth A. Pelkey, Chris J. McBain, James Q. Zheng, Viktor Janos Oláh, Matthew JM Rowan
Publikováno v:
bioRxiv
SummaryThe mammalian brain contains the most diverse array of cell types of any organ, including dozens of neuronal subtypes with distinct anatomical and functional characteristics. The brain leverages these neuron-type-specializations to perform div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4500cb092b7201be8b0254aff475ab0
https://doi.org/10.1101/2023.02.03.527045
https://doi.org/10.1101/2023.02.03.527045