Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Anna E. Fürtjes"'
Autor:
Liliana Garcia-Mondragon, Deniz Konac, Joanne B. Newbury, Katherine S. Young, Alex Ing, Anna E. Fürtjes, Edward D. Barker
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Depression and psychosis are often comorbid; they also have overlapping genetic and environmental risk factors, including trauma and area-level exposures. The present study aimed to advance understanding of this comorbidity via a network app
Externí odkaz:
https://doaj.org/article/a8b4bb49ba614fb5a40b9d1ad98ba85a
Autor:
Oliver Pain, Kylie P Glanville, Saskia P Hagenaars, Saskia Selzam, Anna E Fürtjes, Héléna A Gaspar, Jonathan R I Coleman, Kaili Rimfeld, Gerome Breen, Robert Plomin, Lasse Folkersen, Cathryn M Lewis
Publikováno v:
PLoS Genetics, Vol 17, Iss 5, p e1009021 (2021)
The predictive utility of polygenic scores is increasing, and many polygenic scoring methods are available, but it is unclear which method performs best. This study evaluates the predictive utility of polygenic scoring methods within a reference-stan
Externí odkaz:
https://doaj.org/article/16d89b298f4a47c48c8b77552d412603
Autor:
Anna E. Fürtjes, Ryan Arathimos, Jonathan R. I. Coleman, James H. Cole, Simon R. Cox, Ian J. Deary, Javier de la Fuente, James W. Madole, Elliot M. Tucker‐Drob, Stuart J. Ritchie
Publikováno v:
Fürtjes, A E, Arathimos, R, Coleman, J R I, Cole, J H, Cox, S R, Deary, I J, de la Fuente, J, Madole, J W, Tucker-Drob, E M & Ritchie, S J 2023, ' General dimensions of human brain morphometry inferred from genome-wide association data ', Human Brain Mapping, vol. 44, no. 8, pp. 3311-3323 . https://doi.org/10.1002/hbm.26283
Understanding the neurodegenerative mechanisms underlying cognitive decline in the general population may facilitate early detection of adverse health outcomes in late life. This study investigates genetic links between brain morphometry, ageing and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e970a5d92e95499f38cc6825a5699f1
https://hdl.handle.net/20.500.11820/8eafe787-eb9a-4a3d-acf2-67faf2fe87de
https://hdl.handle.net/20.500.11820/8eafe787-eb9a-4a3d-acf2-67faf2fe87de
Publikováno v:
Cortex
Cortex, 2023, 158, pp.110-126. ⟨10.1016/j.cortex.2022.11.001⟩
Fürtjes, A E, Cole, J H, Couvy-Duchesne, B & Ritchie, S J 2023, ' A quantified comparison of cortical atlases on the basis of trait morphometricity ', Cortex, vol. 158, pp. 110-126 . https://doi.org/10.1016/j.cortex.2022.11.001
Cortex, 2023, 158, pp.110-126. ⟨10.1016/j.cortex.2022.11.001⟩
Fürtjes, A E, Cole, J H, Couvy-Duchesne, B & Ritchie, S J 2023, ' A quantified comparison of cortical atlases on the basis of trait morphometricity ', Cortex, vol. 158, pp. 110-126 . https://doi.org/10.1016/j.cortex.2022.11.001
International audience; Background: Many different brain atlases exist that subdivide the human cortex into dozens or hundreds of regions-of-interest (ROIs). Inconsistency across studies using one or another cortical atlas may contribute to the repli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d92420b0e1a3006e860ff27664175ce
https://pubmed.ncbi.nlm.nih.gov/36516597
https://pubmed.ncbi.nlm.nih.gov/36516597
Publikováno v:
Fürtjes, A E, Coleman, J R I, Tyrrell, J, Lewis, C M & Hagenaars, S P 2022, ' Associations and limited shared genetic aetiology between bipolar disorder and cardiometabolic traits in the UK Biobank ', Psychological Medicine, vol. 52, no. 16, pp. 4039–4048 . https://doi.org/10.1017/S0033291721000945
BackgroundPeople with bipolar disorder (BPD) are more likely to die prematurely, which is partly attributed to comorbid cardiometabolic traits. Previous studies report cardiometabolic abnormalities in BPD, but their shared aetiology remains poorly un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758daaf9fda31345fb7353dba9654bd9
https://doi.org/10.1017/s0033291721000945
https://doi.org/10.1017/s0033291721000945
Autor:
Saskia P. Hagenaars, Cathryn M. Lewis, Lasse Folkersen, Oliver Pain, Kaili Rimfeld, Kylie P. Glanville, Anna E. Fürtjes, Gerome Breen, Saskia Selzam, Jonathan R. I. Coleman
Publikováno v:
Human Molecular Genetics
Pain, O, Glanville, K P, Hagenaars, S, Selzam, S, Fürtjes, A, Coleman, J R I, Rimfeld, K, Breen, G, Folkersen, L & Lewis, C M 2021, ' Imputed gene expression risk scores : A functionally informed component of polygenic risk ', Human Molecular Genetics, vol. 30, no. 8, pp. 727-738 . https://doi.org/10.1093/hmg/ddab053
Pain, O, Glanville, K P, Hagenaars, S, Selzam, S, Fürtjes, A, Coleman, J R I, Rimfeld, K, Breen, G, Folkersen, L & Lewis, C M 2021, ' Imputed gene expression risk scores : A functionally informed component of polygenic risk ', Human Molecular Genetics, vol. 30, no. 8, pp. 727-738 . https://doi.org/10.1093/hmg/ddab053
BackgroundIntegration of functional genomic annotations when estimating polygenic risk scores (PRS) can provide insight into aetiology and improve risk prediction. This study explores the predictive utility of gene expression risk scores (GeRS), calc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d4bb2b19e9eb2cc6e0b7325bc6840a
https://doi.org/10.1093/hmg/ddab053
https://doi.org/10.1093/hmg/ddab053
Autor:
Liliana, Garcia-Mondragon, Deniz, Konac, Joanne B, Newbury, Katherine S, Young, Alex, Ing, Anna E, Fürtjes, Edward D, Barker
Publikováno v:
Translational psychiatry. 12(1)
Depression and psychosis are often comorbid; they also have overlapping genetic and environmental risk factors, including trauma and area-level exposures. The present study aimed to advance understanding of this comorbidity via a network approach, by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::805d1134db3080c0d9cf6f2016e628aa
https://pubmed.ncbi.nlm.nih.gov/35732632
https://pubmed.ncbi.nlm.nih.gov/35732632
Autor:
Elliot M. Tucker-Drob, Javier de la Fuente, Ryan Arathimos, Jonathan R. I. Coleman, Stuart J. Ritchie, Anna E. Fürtjes, Simon R. Cox, Ian J. Deary, James W. Madole, James H. Cole
BackgroundUnderstanding the neurodegenerative mechanisms underlying cognitive declines in the general population may facilitate early detection of adverse health outcomes in late life. This study investigates biological pathways shared between brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e622883ce00490b5a038b64a8262f74
https://doi.org/10.1101/2021.10.22.465437
https://doi.org/10.1101/2021.10.22.465437
Autor:
Abigail ter Kuile, Brittany Mitchell, Alicia Peel, Jessica Mundy, Christopher Hübel, Johan Zvrskovec, Alish Palmos, Jonathan Coleman, Molly Davies, Nick Martin, Enda M. Byrne, Sarah E. Medland, Naomi R. Wray, Brett N. Adey, Sang Hyuck Lee, Anna E. Fürtjes, Geneviève Morneau-Vaillancourt, Kirstin Purves, Megan Skelton, Matthew Hotopf, Daniel J. Smith, David Veale, Chérie Armour, Andrew McIntosh, James T.R. Walters, Ian R. Jones, Colette R. Hirsch, Gursharan Kalsi, Gerome Breen, Thalia Eley
Publikováno v:
European Neuropsychopharmacology. 63:e2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52ae58d20756546dd0604138838a600e
https://doi.org/10.1016/j.euroneuro.2022.07.014
https://doi.org/10.1016/j.euroneuro.2022.07.014
Autor:
Helena Gaspar, Anna E. Fürtjes, Cathryn M. Lewis, Saskia P. Hagenaars, Gerome Breen, Saskia Selzam, Robert Plomin, Kaili Rimfeld, Kylie P. Glanville, Jonathan R. I. Coleman, Lasse Folkersen, Oliver Pain
Publikováno v:
Pain, O, Glanville, K P, Hagenaars, S P, Selzam, S, Fürtjes, A E, Gaspar, H A, Coleman, J R I, Rimfeld, K, Breen, G, Plomin, R, Folkersen, L & Lewis, C M 2021, ' Evaluation of polygenic prediction methodology within a reference-standardized framework ', PLoS Genetics, vol. 17, no. 5, e1009021 . https://doi.org/10.1371/journal.pgen.1009021
PLoS Genetics, Vol 17, Iss 5, p e1009021 (2021)
PLoS Genetics
PLoS Genetics, Vol 17, Iss 5, p e1009021 (2021)
PLoS Genetics
The predictive utility of polygenic scores is increasing, and many polygenic scoring methods are available, but it is unclear which method performs best. This study evaluates the predictive utility of polygenic scoring methods within a reference-stan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2f778959f496c22af63c28f43e184e
https://www.pure.ed.ac.uk/ws/files/361290805/journal.pgen.1009021.pdf
https://www.pure.ed.ac.uk/ws/files/361290805/journal.pgen.1009021.pdf