Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anna E. D'Amico"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Within the bloodstream, monocytes must traverse the microvasculature to prevent leukostasis, which is the entrapment of monocytes within the confines of the microvasculature. Using the model cell line, THP-1, and VCAM-1 coated channels to si
Externí odkaz:
https://doaj.org/article/7949b334626546c6a42d7c76e7e25ec9
Autor:
Mohamed Trebak, Ananya Murali, Michelle R. Lennartz, Anna E. D’Amico, Cheryl M. Zajd, Xuexin Zhang, Alexander C. Wong
Publikováno v:
J Cell Sci
Protein kinase C (PKC)-ε is required for membrane addition during IgG-mediated phagocytosis, but its role in this process is ill defined. Here, we performed high-resolution imaging, which reveals that PKC-ε exits the Golgi and enters phagosomes on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670a6becc2bab8ecd6414ce2430964d
https://doi.org/10.1242/jcs.258886
https://doi.org/10.1242/jcs.258886
Autor:
Anna E. D’Amico, Michelle R. Lennartz
Publikováno v:
Journal of immunological sciences
During phagocytosis, internal membranes are recruited to the site of pathogen binding and fuse with the plasma membrane, providing the membrane needed for pseudopod extension and target uptake. The mechanism by which vesicles destined for the phagoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a55a9e4d882a2556b1da38312b7b344
http://europepmc.org/articles/PMC6089528
http://europepmc.org/articles/PMC6089528
Autor:
Michelle R. Lennartz, Takehiko Ueyama, Naoaki Saito, Nathaniel C. Cady, Cheryl M. Hanes, Margarida Barroso, Alexander C. Wong, Mohamed Trebak, Anna E. D’Amico, W. Frederick Hynes, Xuexin Zhang
Publikováno v:
The Journal of Immunology. 199:271-277
Protein kinase C-ε (PKC-ε) at phagocytic cups mediates the membrane fusion necessary for efficient IgG-mediated phagocytosis. The C1B and pseudosubstrate (εPS) domains are necessary and sufficient for this concentration. C1B binds diacylglycerol;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f44a64e7716e61f03be24cd742c4e8f0
https://doi.org/10.4049/jimmunol.1700243
https://doi.org/10.4049/jimmunol.1700243
Autor:
Sabrina Cribioli, Rachele Alzani, Martino Introna, Michela Bonzi, Rut Valgardsdottir, Maria Chiara Finazzi, Enrico Pesenti, Clara Albanese, Anna E. D’Amico, Gianmaria Borleri, Dirk Nagorsen, Alessandro Rambaldi, Josée Golay, Giulia Quaresmini
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 193(9)
Current treatment of chronic lymphocytic leukemia (CLL) patients often results in life-threatening immunosuppression. Furthermore, CLL is still an incurable disease due to the persistence of residual leukemic cells. These patients may therefore benef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c0805e2281a4478628c70809bbc237
https://pubmed.ncbi.nlm.nih.gov/25267972
https://pubmed.ncbi.nlm.nih.gov/25267972
Publikováno v:
Nucleic Acids Research
Exploration of the epitranscriptome requires the development of highly sensitive and accurate technologies in order to elucidate the contributions of the more than 100 RNA modifications to cell processes. A highly sensitive and accurate ultra-high pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::820d6625da2c98a16d63d3cd8fbb48e3
https://doi.org/10.1093/nar/gkv971
https://doi.org/10.1093/nar/gkv971
Autor:
Anna E. D’Amico, Gianmaria Borleri, Martino Introna, Josée Golay, Maria Chiara Finazzi, Giulia Quaresmini, Alessandro Rambaldi
Publikováno v:
Blood. 122:3272-3272
Background The combined use of chemotherapy and monoclonal antibodies has proved highly effective for the treatment of CLL but often results in severe life threatening immunosuppression. The development of adoptive therapy with autologous T cells cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a31fa6118e0491ff0024aec64dba10ab
https://doi.org/10.1182/blood.v122.21.3272.3272
https://doi.org/10.1182/blood.v122.21.3272.3272