Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Anna Dvorkin‐Gheva"'
Autor:
Xiaotian Ju, Kiho Son, Rameen Jamil, Sarah Culgin, Brittany Salter, Kate Miyasaki, Nahal Emami Fard, Maria Xiao, Zil Patel, Kayla Zhang, Braeden Cowbrough, Melanie Kjarsgaard, Katherine Radford, Anna Dvorkin-Gheva, Carl D. Richards, Gerard Cox, Zain Chagla, Marek Smieja, Marcel Tunks, Waleed Alhazzani, Dawn M.E. Bowdish, Dan Perri, Parameswaran K. Nair, Roma Sehmi, Manali Mukherjee
Publikováno v:
Allergy, Asthma & Clinical Immunology, Vol 19, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/cf86cc4b0ca34fecac9b0c5c7164a921
Autor:
Maria Kondratyev, Aleksandra Pesic, Troy Ketela, Natalie Stickle, Christine Beswick, Zvi Shalev, Stefano Marastoni, Soroush Samadian, Anna Dvorkin-Gheva, Azin Sayad, Mikhail Bashkurov, Pedro Boasquevisque, Alessandro Datti, Trevor J. Pugh, Carl Virtanen, Jason Moffat, Reidar A. Grénman, Marianne Koritzinsky, Bradly G. Wouters
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract During cancer development, tumor cells acquire changes that enable them to invade surrounding tissues and seed metastasis at distant sites. These changes contribute to the aggressiveness of metastatic cancer and interfere with success of the
Externí odkaz:
https://doaj.org/article/886fde5b19b44a0c8e8d3f024a37afbb
Autor:
Mangalakumari Jeyanathan, Dominik K. Fritz, Sam Afkhami, Emilio Aguirre, Karen J. Howie, Anna Zganiacz, Anna Dvorkin-Gheva, Michael R. Thompson, Richard F. Silver, Ruth P. Cusack, Brian D. Lichty, Paul M. O’Byrne, Martin Kolb, Maria Fe C. Medina, Myrna B. Dolovich, Imran Satia, Gail M. Gauvreau, Zhou Xing, Fiona Smaill
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Background Adenovirus-vectored (Ad-vectored) vaccines are typically administered via i.m. injection to humans and are incapable of inducing respiratory mucosal immunity. However, aerosol delivery of Ad-vectored vaccines remains poorly characterized,
Externí odkaz:
https://doaj.org/article/0f5b7f6ff7fa419a8108b00742172faf
Autor:
Branavan Manoranjan, Chitra Venugopal, David Bakhshinyan, Ashley A. Adile, Laura Richards, Michelle M. Kameda-Smith, Owen Whitley, Anna Dvorkin-Gheva, Minomi Subapanditha, Neil Savage, Nazanin Tatari, Dillon McKenna, Blessing Bassey-Archibong, Neil Winegarden, Robin Hallett, John P. Provias, Blake Yarascavitch, Olufemi Ajani, Adam Fleming, Gary D. Bader, Trevor J. Pugh, Bradley W. Doble, Sheila K. Singh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The Wnt molecular subgroup of medulloblastoma is associated with better prognosis than the other molecular subgroups. Here, the authors show that activating Wnt signaling impairs tumor development and improves survival in Group 3 and Group 4 medullob
Externí odkaz:
https://doaj.org/article/90b86d3d0f9c41078f2e0a70337929d5
Autor:
William D. Gwynne, Mirza S. Shakeel, Adele Girgis-Gabardo, Kwang H. Kim, Emily Ford, Anna Dvorkin-Gheva, Craig Aarts, Methvin Isaac, Rima Al-awar, John A. Hassell
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-17 (2020)
Abstract Background Breast tumor initiating cells (BTIC) are stem-like cells that initiate and sustain tumor growth, and drive disease recurrence. Identifying therapies targeting BTIC has been hindered due primarily to their scarcity in tumors. We pr
Externí odkaz:
https://doaj.org/article/8582578dace944f6837d54e4a3840059
Autor:
Joanne A. Hammill, Jacek M. Kwiecien, Anna Dvorkin-Gheva, Vivian W.C. Lau, Christopher Baker, Ying Wu, Ksenia Bezverbnaya, Craig Aarts, Christopher W. Heslen, Galina F. Denisova, Heather Derocher, Katy Milne, Brad H. Nelson, Jonathan L. Bramson
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 278-292 (2020)
Tumor-targeted chimeric antigen receptor (CAR)-engineered T lymphocytes (CAR-T cells) have demonstrated striking clinical success, but their use has been associated with a constellation of toxicities. A better understanding of the pathogenesis of the
Externí odkaz:
https://doaj.org/article/0b7d3e652e9749189e9a98e4bde2c565
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0275864 (2022)
Asthma, an inflammatory disorder of the airways, is one of the most common chronic illnesses worldwide and is associated with significant morbidity. There is growing recognition of an association between asthma and mood disorders including post-traum
Externí odkaz:
https://doaj.org/article/a5a18670bda747bfb8820a0800d04733
Autor:
William D. Gwynne, Mirza S. Shakeel, Jianhan Wu, Robin M. Hallett, Adele Girgis-Gabardo, Anna Dvorkin-Gheva, John A. Hassell
Publikováno v:
Cellular & Molecular Biology Letters, Vol 24, Iss 1, Pp 1-13 (2019)
Abstract Background Breast tumor growth and recurrence are driven by an infrequent population of breast tumor-initiating cells (BTIC). We and others have reported that the frequency of BTIC is orders of magnitude higher when breast tumor cells are pr
Externí odkaz:
https://doaj.org/article/00b38dd4e70b45fc949157a9595cd2a2
Autor:
Steven P. Cass, Olivia Mekhael, Danya Thayaparan, Joshua J. C. McGrath, Spencer D. Revill, Matthew F. Fantauzzi, Peiyao Wang, Amir Reihani, Aaron I. Hayat, Christopher S. Stevenson, Anna Dvorkin-Gheva, Fernando M. Botelho, Martin R. Stämpfli, Kjetil Ask
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
RationaleThe accumulation of macrophages in the airways and the pulmonary interstitium is a hallmark of cigarette smoke-associated inflammation. Notably, pulmonary macrophages are not a homogenous population but consist of several subpopulations. To
Externí odkaz:
https://doaj.org/article/42863354dc984044af4890b5d31645bc
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9653 (2022)
Discovery of the microbiota-gut–brain axis has led to proposed microbe-based therapeutic strategies in mental health, including the use of mood-altering bacterial species, termed psychobiotics. However, we still have limited understanding of the ke
Externí odkaz:
https://doaj.org/article/cee8837c1d72458fb56084ca40809b7a