Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Anna Durrans"'
Autor:
Marcin Stawowczyk, Max D. Wellenstein, Sharrell B. Lee, Shira Yomtoubian, Anna Durrans, Hyejin Choi, Navneet Narula, Nasser K. Altorki, Dingcheng Gao, Vivek Mittal
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 2, Pp 55-64 (2017)
Molecularly targeted therapies benefit approximately 15–20% of non-small cell lung cancer (NSCLC) patients carrying specific drug-sensitive mutations. Thus, there is a clinically unmet need for the identification of novel targets for drug developme
Externí odkaz:
https://doaj.org/article/97075bf7c3e04161aaec3dbf287501d4
Autor:
Hyejin Choi, Jianting Sheng, Dingcheng Gao, Fuhai Li, Anna Durrans, Seongho Ryu, Sharrell B. Lee, Navneet Narula, Shahin Rafii, Olivier Elemento, Nasser K. Altorki, Stephen T.C. Wong, Vivek Mittal
Publikováno v:
Cell Reports, Vol 10, Iss 7, Pp 1187-1201 (2015)
Emerging studies have begun to demonstrate that reprogrammed stromal cells play pivotal roles in tumor growth, metastasis, and resistance to therapy. However, the contribution of stromal cells to non-small-cell lung cancer (NSCLC) has remained undere
Externí odkaz:
https://doaj.org/article/b8dcb02418354e378974693d3b80fe53
Autor:
Anna Durrans, Dingcheng Gao, Ravi Gupta, Kari R Fischer, Hyejin Choi, Tina El Rayes, Seongho Ryu, Abu Nasar, Cathy F Spinelli, Weston Andrews, Olivier Elemento, Daniel Nolan, Brendon Stiles, Shahin Rafii, Navneet Narula, Ramana Davuluri, Nasser K Altorki, Vivek Mittal
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129123 (2015)
Lung cancer is the leading cause of cancer related mortality worldwide, with non-small cell lung cancer (NSCLC) as the most prevalent form. Despite advances in treatment options including minimally invasive surgery, CT-guided radiation, novel chemoth
Externí odkaz:
https://doaj.org/article/2ee6bf417a6b4758a056f33c3cf94660
Autor:
Hyejin Choi, Anna Durrans, Max D. Wellenstein, Marcin Stawowczyk, Dingcheng Gao, Vivek Mittal, Sharrell Lee, Shira Yomtoubian, Navneet Narula, Nasser K. Altorki
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 2, Pp 55-64 (2017)
Molecularly targeted therapies benefit approximately 15–20% of non-small cell lung cancer (NSCLC) patients carrying specific drug-sensitive mutations. Thus, there is a clinically unmet need for the identification of novel targets for drug developme
Autor:
Dingcheng Gao, Nasser K. Altorki, Shahin Rafii, Navneet Narula, Sharrell Lee, Vivek Mittal, Fuhai Li, Stephen T. C. Wong, Anna Durrans, Hyejin Choi, Jianting Sheng, Seongho Ryu, Olivier Elemento
Publikováno v:
Cell Reports, Vol 10, Iss 7, Pp 1187-1201 (2015)
SummaryEmerging studies have begun to demonstrate that reprogrammed stromal cells play pivotal roles in tumor growth, metastasis, and resistance to therapy. However, the contribution of stromal cells to non-small-cell lung cancer (NSCLC) has remained
Autor:
Stephen T. C. Wong, Tina El Rayes, Anna Durrans, Linda T. Vahdat, Jianting Sheng, Fuhai Li, Seongho Ryu, Hyejin Choi, Vivek Mittal, Sharrell Lee, Dingcheng Gao, Kari R. Fischer, Robert F. Schwabe, Nasser K. Altorki, Juliane S. Troeger
Publikováno v:
J Pharmacol Clin Trials
Nature
Nature
The role of epithelial-to-mesenchymal transition (EMT) in metastasis is a longstanding source of debate, largely owing to an inability to monitor transient and reversible EMT phenotypes in vivo. Here we establish an EMT lineage-tracing system to moni
Autor:
Vivek Mittal, Fuhai Li, Stephen T. C. Wong, Anna Durrans, Hyejin Choi, Kari R. Fischer, Dingcheng Gao, Jianting Sheng, Nasser K. Altorki, Sharrell Lee
Publikováno v:
Cancer Research. 75:4721-4721
The role of epithelial to mesenchymal transition (EMT) in metastasis is a longstanding source of controversy, largely due to an inability to monitor transient and reversible EMT phenotypes in vivo. We have established a novel and unique EMT lineage t
Autor:
Jianting Shen, Vivek Mittal, Kari R. Fischer, Dingcheng Gao, Hyejin Choi, Tina El Rayes, Steve Wong, Nasser K. Altorki, Anna Durrans
Publikováno v:
Cancer Research. 75:3214-3214
We have systematically dissected the microenvironmental hetereogeneity of lung adenocarcinomas, and provide cellular and molecular landscapes that contribute to carcinogenesis. RNA deep sequencing analysis of individually sorted stromal and tumor epi
Autor:
Sharrell Lee, Dingcheng Gao, Vivek Mittal, Seongho Ryu, Stephen T. C. Wong, Hyejin Choi, Anna Durrans, Nasser K. Altorki, Olivier Elemento
Publikováno v:
Cancer Research. 74:1159-1159
Lung cancer is a leading cause of deaths from cancer among men and women worldwide with an estimated 1.5 million deaths each year. Available molecularly targeted therapies benefit a limited number of patients and even in these patients acquired resis
Publikováno v:
The FASEB Journal. 23