PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge

Autor: Thomas Southworth, Sarah Mason, Alan Bell, Isabel Ramis, Marta Calbet, Anna Domenech, Neus Prats, Montserrat Miralpeix, Dave Singh

Publikováno v: Biomarker Research, Vol 6, Iss 1, Pp 1-8 (2018)

Abstract Background Inhaled allergen challenges are often used to evaluate novel asthma treatments in early phase clinical trials. Current novel therapeutic targets in asthma include phosphoinositide 3-kinases (PI3K) delta and gamma, p38 mitogen-acti

Externí odkaz: https://doaj.org/article/61ebe37767d74f31aad86d3cf15f3621

Feasibility and outcomes of transjugular intrahepatic portosystemic shunts in infants

Autor: José J. Martínez-Rodrigo, Ali Boukhoubza, Daniel Pérez Enguix, Raúl García-Marcos, Juan J. Vila-Carbó, Anna Domenech, Cinta Sangüesa Nebot, Jimena Solana, Luis Marti-Bonmatí

Publikováno v: Pediatric Radiology. 53:953-962

Experience with transjugular intrahepatic portosystemic shunts (TIPS) in the pediatric population, especially in infants, is limited.To evaluate the feasibility, efficacy and safety of TIPS placement in infants.This retrospective non-comparative obse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46db0f9febbd7fcf69a26aeb0c0c2856
https://doi.org/10.1007/s00247-022-05575-5

Soil organic matter properties drive microbial enzyme activities and greenhouse gas fluxes along an elevational gradient

Autor: Xingguo Han, Anna Doménech-Pascual, Joan Pere Casas-Ruiz, Jonathan Donhauser, Karen Jordaan, Jean-Baptiste Ramond, Anders Priemé, Anna M. Romaní, Aline Frossard

Publikováno v: Geoderma, Vol 449, Iss , Pp 116993- (2024)

Mountain ecosystems, contributing substantially to the global carbon (C) and nitrogen (N) biogeochemical cycles, are heavily impacted by global changes. Although soil respiration and microbial activities have been extensively studied at different ele

Externí odkaz: https://doaj.org/article/513ac69109aa41d3b05eaeb2a89bb537

Onset and progression of postmortem histological changes in the central nervous system of RccHan™: WIST rats

Autor: Klaus Weber, Anna Domènech, Kristel Kegler, Robert Kreutzer, Francisco José Mayoral, Yoshimasa Okazaki, Paula Ortega, Laura Polledo, Tanja Razinger, Olivia Kristina Richard, Raúl Sanchez, Nils Warfving, Raquel Vallejo, Ricardo de Miguel

Publikováno v: Frontiers in Veterinary Science, Vol 11 (2024)

Death initiates a cascade of physiological and biochemical alterations in organs and tissues, resulting in microscopic changes that challenge the histopathological evaluation. Moreover, the brain is particularly susceptible to artifacts owing to its

Externí odkaz: https://doaj.org/article/b8d3f3359ab1447eb9228dd5de30a5b6

Biosynthesis and Cellular Localization of Functional Polyketides in the Gastropod Mollusc Scaphander lignarius

Autor: Guido Cimino, Giovanna Romano, Annamaria Rosica, Adele Cutignano, Angelo Fontana, Ernesto Mollo, Conxita Avila, Bruna Laratta, Anna Domenech-Coll

Publikováno v: ChemBioChem
13 (2012): 1759–1766. doi:10.1002/cbic.201200287
info:cnr-pdr/source/autori:A. Cutignano; C. Avila; A. Rosica; G. Romano; B. Laratta; A. Domenech-Coll; G. Cimino; E. Mollo; A. Fontana/titolo:Biosynthesis and cellular localization of functional polyketides in the gastropod mollusc Scaphander lignarius/doi:10.1002%2Fcbic.201200287/rivista:ChemBioChem (Print)/anno:2012/pagina_da:1759/pagina_a:1766/intervallo_pagine:1759–1766/volume:13

Opisthobranchs belong to a subclass of highly evolved and specialised marine gastropods that rely on the use of secondary metabolites for their survival. Here we report the full elucidation of the biosynthesis of aromatic metabolites, lignarenones, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddad0c43cae0e91d82038c00149b014
https://doi.org/10.1002/cbic.201200287