Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment

Autor: Sonia Leite, Christel Herold-Mende, Anna Dirkse, Dzjemma Sarkisjan, Daniel Stieber, Nicolaas H. C. Brons, Sabrina Fritah, Thomas Buder, Rolf Bjerkvig, Anja Voss-Böhme, Francisco Azuaje, Andreas Deutsch, Simone P. Niclou, Nicolas Sauvageot, Frank Hertel, Alesandro Michelucci, Mathieu Seyfrid, Petr V. Nazarov, Anna Golebiewska, Alexander Skupin, Suresh Poovathingal, Arnaud Muller

Publikováno v: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Dirkse, A, Golebiewska, A, Buder, T, Nazarov, P V, Muller, A, Poovathingal, S, Brons, N H C, Leite, S, Sauvageot, N, Sarkisjan, D, Seyfrid, M, Fritah, S, Stieber, D, Michelucci, A, Hertel, F, Herold-Mende, C, Azuaje, F, Skupin, A, Bjerkvig, R, Deutsch, A, Voss-Böhme, A & Niclou, S P 2019, ' Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment ', Nature Communications, vol. 10, no. 1, 1787 . https://doi.org/10.1038/s41467-019-09853-z
Nature Communications, 10(1):1787. Nature Publishing Group

The identity and unique capacity of cancer stem cells (CSC) to drive tumor growth and resistance have been challenged in brain tumors. Here we report that cells expressing CSC-associated cell membrane markers in Glioblastoma (GBM) do not represent a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41916d135cd4cd09182249c39df34022
https://hdl.handle.net/1956/22507