Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Anna Di Matteo"'
Autor:
Davide Pradella, Gianluca Deflorian, Alex Pezzotta, Anna Di Matteo, Elisa Belloni, Daniele Campolungo, Andrea Paradisi, Mattia Bugatti, William Vermi, Matteo Campioni, Antonella Chiapparino, Luigi Scietti, Federico Forneris, Costanza Giampietro, Nina Volf, Michael Rehman, Serena Zacchigna, Maria Paola Paronetto, Anna Pistocchi, Anne Eichmann, Patrick Mehlen, Claudia Ghigna
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
UNC5B is a Netrin-1 receptor expressed in endothelial cells that in the absence of ligand induces apoptosis. Here the authors identify an UNC5B splicing isoform that is insensitive to the pro-survival ligand Netrin-1 and is required for apoptosis-dep
Externí odkaz:
https://doaj.org/article/bc552c64149c47869cf73be5501499a0
Autor:
Anna Di Matteo, Elisa Belloni, Davide Pradella, Ambra Cappelletto, Nina Volf, Serena Zacchigna, Claudia Ghigna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-19 (2020)
Abstract Alternative splicing (AS) is a pervasive molecular process generating multiple protein isoforms, from a single gene. It plays fundamental roles during development, differentiation and maintenance of tissue homeostasis, while aberrant AS is c
Externí odkaz:
https://doaj.org/article/ff0b01acf4e14a90b143c5b7c6634b64
Autor:
Beatrice Garrone, Anna di Matteo, Alessandro Amato, Luana Pistillo, Lucia Durando, Claudio Milanese, Francesco Paolo Di Giorgio, Serena Tongiani
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0244649 (2021)
Neuropathic pain is a chronic debilitating condition caused by injury or disease of the nerves of the somatosensory system. Although several therapeutic approaches are recommended, none has emerged as an optimal treatment leaving a need for developin
Externí odkaz:
https://doaj.org/article/47d01d0e94f94e4781f98b371364cc85
Autor:
Francesca Angiolini, Elisa Belloni, Marco Giordano, Matteo Campioni, Federico Forneris, Maria Paola Paronetto, Michela Lupia, Chiara Brandas, Davide Pradella, Anna Di Matteo, Costanza Giampietro, Giovanna Jodice, Chiara Luise, Giovanni Bertalot, Stefano Freddi, Matteo Malinverno, Manuel Irimia, Jon D Moulton, James Summerton, Antonella Chiapparino, Carmen Ghilardi, Raffaella Giavazzi, Daniel Nyqvist, Davide Gabellini, Elisabetta Dejana, Ugo Cavallaro, Claudia Ghigna
Publikováno v:
eLife, Vol 8 (2019)
The biological players involved in angiogenesis are only partially defined. Here, we report that endothelial cells (ECs) express a novel isoform of the cell-surface adhesion molecule L1CAM, termed L1-ΔTM. The splicing factor NOVA2, which binds direc
Externí odkaz:
https://doaj.org/article/376dd173fafe4dde820cc904b3e48e1d
Autor:
Anna Di Matteo, Elisa Belloni, Davide Pradella, Anna Maria Chiaravalli, Giacomo Maria Pini, Mattia Bugatti, Roberta Alfieri, Chiara Barzan, Elena Franganillo Tena, Silvia Bione, Elisa Terenzani, Fausto Sessa, Christopher D. R. Wyatt, William Vermi, Claudia Ghigna
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8102
Angiogenesis is crucial for cancer progression. While several anti-angiogenic drugs are in use for cancer treatment, their clinical benefits are unsatisfactory. Thus, a deeper understanding of the mechanisms sustaining cancer vessel growth is fundame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f84be97022ded8faaeac8a7daa07ac
Autor:
Francesco Paolo Di Giorgio, Claudia Cavarischia, Graziella Bovi, Rosella Ombrato, Anna di Matteo, Rosa Buonfiglio, Pier Francesca Porceddu, Rossella Picollo, Beatrice Garrone, Guido Furlotti, Laura Oggianu, Silvana Olivieri, Giorgina Mangano, Federica Prati, Angelo Reggiani
Publikováno v:
ACS Medicinal Chemistry Letters. 11:825-831
Bipolar disorders still represent a global unmet medical need and pose a requirement for novel effective treatments. In this respect, glycogen synthase kinase 3β (GSK-3β) aberrant activity has been linked to the pathophysiology of several disease c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ae7dd0fd876adbd552f66cdec8f8128
https://doi.org/10.1021/acsmedchemlett.9b00633
https://doi.org/10.1021/acsmedchemlett.9b00633
Autor:
Matilde Monti, Jacopo Celli, Francesco Missale, Francesca Cersosimo, Mariapia Russo, Elisa Belloni, Anna Di Matteo, Silvia Lonardi, William Vermi, Claudia Ghigna, Emanuele Giurisato
Publikováno v:
Cancers
Cancers, Vol 14, Iss 348, p 348 (2022)
Cancers, Vol 14, Iss 348, p 348 (2022)
Simple Summary Alterations of the MEK5/ERK5 signaling pathway have been described in several tumors, and emerging data are trying to explain the complexity of ERK5-related mechanisms in both physiological and pathological conditions. Here, we provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44007614953b55a3d7c93740714cf2e
http://hdl.handle.net/11379/551521
http://hdl.handle.net/11379/551521
Autor:
Alex Pezzotta, Anna Pistocchi, Patrick Mehlen, Andrea Paradisi, Anna Di Matteo, Federico Forneris, Daniele Campolungo, Costanza Giampietro, Elisa Belloni, Gianluca Deflorian, Nina Volf, Antonella Chiapparino, Michael Rehman, William Vermi, Maria Paola Paronetto, Mattia Bugatti, Davide Pradella, Claudia Ghigna, Anne Eichmann, Matteo Campioni, Serena Zacchigna, Luigi Scietti
Publikováno v:
Nature Communications
Nature Communications, 2021, 12 (1), pp.4872. ⟨10.1038/s41467-021-24998-6⟩
Nature Communications, 12
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.4872. ⟨10.1038/s41467-021-24998-6⟩
Nature Communications, 2021, 12 (1), pp.4872. ⟨10.1038/s41467-021-24998-6⟩
Nature Communications, 12
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.4872. ⟨10.1038/s41467-021-24998-6⟩
The Netrin-1 receptor UNC5B is an axon guidance regulator that is also expressed in endothelial cells (ECs), where it finely controls developmental and tumor angiogenesis. In the absence of Netrin-1, UNC5B induces apoptosis that is blocked upon Netri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b474c65ef53add8d7c9ee805789f290
https://doi.org/10.1038/s41467-021-24998-6
https://doi.org/10.1038/s41467-021-24998-6
Autor:
Claudia Ghigna, Hairi Li, Namjeong Choi, Xuexiu Zheng, Jiyeon Ha, Haihong Shen, Yoonseong Kim, Changwei Shao, Jagyeong Oh, Xiang-Dong Fu, Davide Pradella, Anna Di Matteo
Publikováno v:
Cancers
Volume 13
Issue 12
Cancers, Vol 13, Iss 3071, p 3071 (2021)
Cancers, vol 13, iss 12
Volume 13
Issue 12
Cancers, Vol 13, Iss 3071, p 3071 (2021)
Cancers, vol 13, iss 12
Simple Summary Aberrant alternative splicing (AS) regulation plays a pivotal role in breast cancer development, progression, and resistance to therapeutical interventions. Indeed, cancer cells can adapt their own transcriptome by changing different A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a65a969ccaac84359bdc7414b66f55
Autor:
Federica, Prati, Rosa, Buonfiglio, Guido, Furlotti, Claudia, Cavarischia, Giorgina, Mangano, Rossella, Picollo, Laura, Oggianu, Anna, di Matteo, Silvana, Olivieri, Graziella, Bovi, Pier Francesca, Porceddu, Angelo, Reggiani, Beatrice, Garrone, Francesco Paolo, Di Giorgio, Rosella, Ombrato
Publikováno v:
ACS Med Chem Lett
[Image: see text] Bipolar disorders still represent a global unmet medical need and pose a requirement for novel effective treatments. In this respect, glycogen synthase kinase 3β (GSK-3β) aberrant activity has been linked to the pathophysiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a36bfd0764fb991dc9b935ea2e2755a0
https://pubmed.ncbi.nlm.nih.gov/32435391
https://pubmed.ncbi.nlm.nih.gov/32435391