Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Anna Dewenter"'
Autor:
Nicolai Franzmeier, Amir Dehsarvi, Anna Steward, Davina Biel, Anna Dewenter, Sebastian Niclas Roemer, Fabian Wagner, Mattes Groß, Matthias Brendel, Alexis Moscoso, Prithvi Arunachalam, Kaj Blennow, Henrik Zetterberg, Michael Ewers, Michael Schöll
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract In Alzheimer’s disease, amyloid-beta (Aβ) triggers the trans-synaptic spread of tau pathology, and aberrant synaptic activity has been shown to promote tau spreading. Aβ induces aberrant synaptic activity, manifesting in increases in the
Externí odkaz:
https://doaj.org/article/805dd9e85c8145c99b2ccade83ebcf4a
Autor:
Annemieketer Telgte, Anna Dewenter, Benno Gesierich, Nadja Gruber, Anna Kopczak, Marco Duering
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100297- (2024)
Introduction: Due to increasing availability of MRI scans, incidental diffusion-weighted imaging (DWI)-positive lesions are increasingly recognized on brain MRI in individuals with vascular disease. Cerebral small vessel disease (SVD) is a putative c
Externí odkaz:
https://doaj.org/article/75d8cb490d68479991ead13a601773c7
Autor:
Bruno Miguel de Brito Robalo, Geert Jan Biessels, Christopher Chen, Anna Dewenter, Marco Duering, Saima Hilal, Huiberdina L. Koek, Anna Kopczak, Bonnie Lam, Alexander Leemans, Vincent Mok, Laurien P. Onkenhout, Hilde van den Brink, Alberto de Luca
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 6, Iss , Pp 100104- (2024)
Externí odkaz:
https://doaj.org/article/b63fcb92b56e4220ad84d4784abc5a2e
Autor:
Davina Biel, Ying Luan, Matthias Brendel, Paul Hager, Anna Dewenter, Alexis Moscoso, Diana Otero Svaldi, Ixavier A. Higgins, Michael Pontecorvo, Sebastian Römer, Anna Steward, Anna Rubinski, Lukai Zheng, Michael Schöll, Sergey Shcherbinin, Michael Ewers, Nicolai Franzmeier, the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2022)
Abstract Background Tau-PET is a prognostic marker for cognitive decline in Alzheimer’s disease, and the heterogeneity of tau-PET patterns matches cognitive symptom heterogeneity. Thus, tau-PET may allow precision-medicine prediction of individual
Externí odkaz:
https://doaj.org/article/ccfa8ae4ae3c45568c2230133b4c334b
Autor:
Anna Rubinski, Nicolai Franzmeier, Anna Dewenter, Ying Luan, Ruben Smith, Olof Strandberg, Rik Ossenkoppele, Martin Dichgans, Oskar Hansson, Michael Ewers, the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background In Alzheimer’s disease (AD), fibrillar tau initially occurs locally and progresses preferentially between closely connected regions. However, the underlying sources of regional vulnerability to tau pathology remain unclear. Prev
Externí odkaz:
https://doaj.org/article/06f1a6bae9d74d0782c1d4ebcb60ec24
Autor:
Lukas Frontzkowski, Michael Ewers, Matthias Brendel, Davina Biel, Rik Ossenkoppele, Paul Hager, Anna Steward, Anna Dewenter, Sebastian Römer, Anna Rubinski, Katharina Buerger, Daniel Janowitz, Alexa Pichet Binette, Ruben Smith, Olof Strandberg, Niklas Mattsson Carlgren, Martin Dichgans, Oskar Hansson, Nicolai Franzmeier
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Individuals with young onset sporadic Alzheimer’s disease show faster pathological and clinical progression. Here the authors report that earlier symptom onset in Alzheimer’s disease is associated with higher tau pathology in globally connected b
Externí odkaz:
https://doaj.org/article/e1741019979b493fa3b111ba1f20853a
Autor:
Davina Biel, Marc Suárez‐Calvet, Paul Hager, Anna Rubinski, Anna Dewenter, Anna Steward, Sebastian Roemer, Michael Ewers, Christian Haass, Matthias Brendel, Nicolai Franzmeier, the Alzheimer's Disease Neuroimaging Initiative (ADNI)
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Microglial activation occurs early in Alzheimer's disease (AD) and previous studies reported both detrimental and protective effects of microglia on AD progression. Here, we used CSF sTREM2 to investigate disease stage‐dependent drivers of
Externí odkaz:
https://doaj.org/article/ea66371c81c9496c92efbf79d69b23c9
Autor:
Mirthe Coenen, Geert Jan Biessels, Charles DeCarli, Evan F. Fletcher, Pauline M. Maillard, Frederik Barkhof, Josephine Barnes, Thomas Benke, Jooske M.F. Boomsma, Christopher P.L.H. Chen, Peter Dal-Bianco, Anna Dewenter, Marco Duering, Christian Enzinger, Michael Ewers, Lieza G. Exalto, Nicolai Franzmeier, Onno Groeneveld, Saima Hilal, Edith Hofer, Huiberdina L. Koek, Andrea B. Maier, Cheryl R. McCreary, Janne M. Papma, Ross W. Paterson, Yolande A.L. Pijnenburg, Anna Rubinski, Reinhold Schmidt, Jonathan M. Schott, Catherine F. Slattery, Eric E. Smith, Carole H. Sudre, Rebecca M.E. Steketee, Esther van den Berg, Wiesje M. van der Flier, Narayanaswamy Venketasubramanian, Meike W. Vernooij, Frank J. Wolters, Xu Xin, J. Matthijs Biesbroek, Hugo J. Kuijf
Publikováno v:
NeuroImage: Clinical, Vol 40, Iss , Pp 103547- (2023)
Introduction: The spatial distribution of white matter hyperintensities (WMH) on MRI is often considered in the diagnostic evaluation of patients with cognitive problems. In some patients, clinicians may classify WMH patterns as “unusual”, but th
Externí odkaz:
https://doaj.org/article/5540ab7b51b04a4e98f8f59244635cc5
Autor:
Bruno M. de Brito Robalo, Alberto de Luca, Christopher Chen, Anna Dewenter, Marco Duering, Saima Hilal, Huiberdina L. Koek, Anna Kopczak, Bonnie Yin Ka Lam, Alexander Leemans, Vincent Mok, Laurien P. Onkenhout, Hilde van den Brink, Geert Jan Biessels
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103217- (2022)
Purpose: To investigate if network thresholding and raw data harmonization improve consistency of diffusion MRI (dMRI)-based brain networks while also increasing precision and sensitivity to detect disease effects in multicentre datasets. Methods: Br
Externí odkaz:
https://doaj.org/article/451dcf820840454294356af8a2be86fe
Autor:
Bruno M. de Brito Robalo, Geert Jan Biessels, Christopher Chen, Anna Dewenter, Marco Duering, Saima Hilal, Huiberdina L. Koek, Anna Kopczak, Bonnie Yin Ka Lam, Alexander Leemans, Vincent Mok, Laurien P. Onkenhout, Hilde van den Brink, Alberto de Luca
Publikováno v:
NeuroImage: Clinical, Vol 32, Iss , Pp 102886- (2021)
Objectives: Acquisition-related differences in diffusion magnetic resonance imaging (dMRI) hamper pooling of multicentre data to achieve large sample sizes. A promising solution is to harmonize the raw diffusion signal using rotation invariant spheri
Externí odkaz:
https://doaj.org/article/11ff756994d94119bbbf4bffb35bdbd4